[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616138":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":33,"locations":43,"responsibleParty":65,"collaborators":11,"id":67,"slug":11,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":11,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":11,"studyType":79,"phases":80,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":46,"whyStopped":11,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Uniformed Services University of the Health Sciences","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Myofunctional Therapy","EXPERIMENTAL",null,[13],"Behavioral: High-Resistance Breathing and Drinking Exercises",{"label":15,"type":16,"description":11,"interventionNames":17},"Relaxation Therapy","SHAM_COMPARATOR",[18],"Behavioral: Low-Resistance Breathing and Drinking Exercises",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","High-Resistance Breathing and Drinking Exercises","Three months of drinking at least 32-oz of water daily through a high-resistance nozzle, and inhaling and exhaling 60 times per day through a high-resistance breathing device",[9],[26],"Device-Assisted Myofunctional Therapy",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Low-Resistance Breathing and Drinking Exercises","Three months of drinking 32-oz of water daily through a low-resistance nozzle, and inhaling and exhaling 40 times per day through a low-resistance breathing device",[15],[32],"Placebo Therapy",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Nancy P. Solomon, Ph.D.","CONTACT","301-319-7042","nancy.p.solomon.civ@health.mil",{"name":40,"role":36,"phone":11,"phoneExt":41,"email":42},"Kathleen M. Moran, Ed.D","443-776-1689","kmoran@genevausa.org",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Walter Reed National Military Medical Center","RECRUITING","Bethesda","Maryland","20889","United States",{"type":52,"coordinates":53},"Point",[54,55],-77.10026,38.98067,{"lat":55,"lon":54},[58,61,63],{"name":59,"role":36,"phone":60,"phoneExt":41,"email":42},"Kathleen M. Moran, Ed.D.","574-344-8933",{"name":35,"role":62,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"name":64,"role":62,"phone":11,"phoneExt":11,"email":11},"Kent Werner, MD, PhD",{"type":66,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100616138",false,"NCT07301710","Low-Tech Treatments for Obstructive Sleep Apnea","Myofunctional Therapy for Obstructive Sleep Apnea in U.S. Service Members With and Without Traumatic Brain Injury","Inclusion Criteria:\n\n* New diagnosis of OSA (AHI, ≥ 5) or failure of first-line OSA treatment;\n* Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months;\n* Ability to follow directions and perform the required exercises;\n* Age between 18-65 yr.\n\nExclusion Criteria:\n\n* Current use of OSA treatment;\n* Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia);\n* Severe nasal obstruction; 4) severe ankyloglossia; 4) craniofacial abnormality; 5) severe pulmonary disease; 6) severe post-traumatic stress disorder; 7) very severe insomnia; 8) body mass index (BMI) ≥30 kg\u002Fm2","ALL","18 Years","65 Years",{"count":77,"type":78},60,"ESTIMATED","INTERVENTIONAL",[81,82],"PHASE1","PHASE2","The overall purpose of this study is to compare changes in sleep outcomes in people with obstructive sleep apnea (OSA) depending on their participation in one of two behavioral interventions; both involve drinking water and breathing. A second purpose is to compare outcomes between people who have sustained a traumatic brain injury (TBI) and those with no history of TBI. The main questions it aims to answer are whether sleep quality improves after 3-months of high-resistance versus low-resistance exercises, and whether people have different outcomes depending on their history of TBI.",[85,86],"Obstructive Sleep Apnea (OSA)","Traumatic Brain Injury (TBI)",[88,9,89,90,91,92],"Obstructive Sleep Apnea","Traumatic Brain Injury","Randomized Controlled Trial","Oropharyngeal Exercises","Respiratory Resistance Training","2026-02-11",{"date":95,"type":96},"2026-02-17","ACTUAL",{"date":98,"type":96},"2026-01-29",{"date":100,"type":78},"2027-12",{"name":5,"class":6},1]