This study will evaluate the efficacy and non-inferiority of a non-surgical approach for the treatment of patients with locally advanced breast cancer.
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
Male or female, aged 18 years or older
Early-stage breast cancer diagnosis (cT1-3 N0 or cT1-2 N1) and a Human Epidermal Receptor 2 (HER2)-positive or triple negative breast cancer (TNBC) tumor molecular subtype
Pregnancy or lactation
Inmate or prisoner
Treatment with an investigational drug or other intervention throughout their breast cancer treatment
Patients with skin involvement and/or distant metastases
Ohio State University Comprehensive Cancer Center
Lead sponsor
Gateway for Cancer Research
Collaborator