[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100450608":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":20,"locations":25,"responsibleParty":56,"collaborators":20,"id":58,"slug":20,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":20,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":20,"maxAge":20,"enrollmentInfo":65,"targetDuration":20,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":79,"overallStatus":28,"whyStopped":20,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"The Foundation for Orthopaedics and Regenerative Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment Group (AlloRx)","EXPERIMENTAL","intravenous and sub-tenon delivery (total dose of 100 million cells)",[13],"Biological: AlloRx",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","AlloRx","cultured allogeneic adult umbilical cord derived mesenchymal stem cells",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Chadwick Prodromos, MD","PRINCIPAL_INVESTIGATOR",[26,43],{"facility":27,"status":28,"city":29,"state":20,"zip":20,"country":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Medical Surgical Associates Center","RECRUITING","St John's","Antigua and Barbuda",{"type":32,"coordinates":33},"Point",[34,35],-61.84329,17.12096,{"lat":35,"lon":34},[38],{"name":39,"role":40,"phone":41,"phoneExt":20,"email":42},"Chadwick Prodromos, M.D.","CONTACT","8476996810","care@thepsci.com",{"facility":44,"status":28,"city":45,"state":20,"zip":20,"country":46,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"Center for Investigation in Tissue Engineering and Cellular Therapy","Buenos Aires","Argentina",{"type":32,"coordinates":48},[49,50],-58.37723,-34.61315,{"lat":50,"lon":49},[53],{"name":39,"role":40,"phone":41,"phoneExt":54,"email":55},"202","Care@thepsci.com",{"type":57,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100450608",false,"NCT05147701","Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION","Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Non-arteritic Ischemic Optic Neuropathy","Inclusion Criteria:\n\n* Diagnosis of NAION (non-arteritic ischemic optic neuropathy)\n* Understanding and willingness to sign a written informed consent document\n\nExclusion Criteria:\n\n* Active infection\n* Active cancer\n* Chronic multisystem organ failure\n* Pregnancy\n* Clinically significant Abnormalities on pre-treatment laboratory evaluation\n* Medical condition that would (based on the opinion of the investigator) compromise patient's safety.\n* Continued drug abuse\n* Pre-menopausal women not using contraception\n* Previous organ transplant\n* Hypersensitivity to sulfur","ALL",{"count":66,"type":67},20,"ESTIMATED","INTERVENTIONAL",[70],"PHASE1","This trial will study the safety and efficacy of intravenous and sub-tenon delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of non-arteritic ischemic optic neuropathy",[73,74,75,76,77,78],"Eye Diseases","Retinitis Pigmentosa","Diabetic Retinopathy","Macular Degeneration","Traumatic Optic Neuropathy","Optic Atrophy",[73,74,80,75,76,77,78],"stem cell treatment","2025-04-15",{"date":83,"type":84},"2025-04-17","ACTUAL",{"date":86,"type":84},"2022-02-01",{"date":88,"type":67},"2026-01",{"name":5,"class":6},2]