5-Day Preoperative Radiation for Soft Tissue Sarcoma
ConditionSoft Tissue Sarcoma
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorStanford University
About this trial
The purpose of this study is to examine the safety and efficacy of an abbreviated course of preoperative radiation, given over five days, for patients with soft tissue sarcoma of the extremity, trunk or retroperitoneum. This is in contrast to standard preoperative radiation, which is given over 25 days.
Eligibility criteria
Qualifiers
Histologically confirmed soft tissue sarcoma of the extremity, trunk or retroperitoneum.
Has been offered preoperative radiation and surgery as part of standard-of-care treatment
Age ≥ 18
KPS ≥ 70 or ECOG 0 to 2
Disqualifiers
History of prior radiation to the area to be treated.
Active use of other anti-cancer investigational agents.
Planned use of concurrent chemotherapy, targeted therapy, or immunotherapy with radiation therapy (defined as the time interval starting 1 week before the first and last fraction of radiation therapy and surgery).
Pregnancy.
Trial design
Treatments tested in this trial
- External Beam Radiotherapy
Treatment groups
75 Participants
are divided into 1 treatment groupLocations
1Stanford University94305, Palo AltoCalifornia, United States
Sponsors and collaborators
Stanford University
Lead sponsor
Source ClinicalTrials.gov