[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617087":3},{"organization":4,"outcomesModule":7,"designInfo":77,"detailedDescription":76,"studyPopulation":76,"armGroups":88,"interventions":100,"overallOfficials":76,"centralContacts":108,"locations":114,"responsibleParty":553,"collaborators":76,"id":555,"slug":76,"hasResults":556,"nctId":557,"briefTitle":558,"officialTitle":559,"acronym":76,"eligibilityCriteria":560,"healthyVolunteers":556,"sex":561,"minAge":562,"maxAge":563,"enrollmentInfo":564,"targetDuration":76,"studyType":567,"phases":568,"briefSummary":570,"conditions":571,"keywords":76,"overallStatus":117,"whyStopped":76,"lastUpdateSubmitDate":573,"lastUpdatePostDateStruct":574,"startDateStruct":577,"completionDateStruct":579,"leadSponsor":581,"locationsCount":582},{"fullName":5,"class":6},"Chia Tai Tianqing Pharmaceutical Group Co., Ltd.","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":76},[9],{"measure":10,"description":11,"timeFrame":12},"Percentage of patients with a score of 0 for the pustule subterm","Percentage of patients with a Physician's Global Assessment of Generalized Pustular Psoriasis (GPPGA) pustular subitem of 0 (no visible pustules) at week 1 among all enrolled patients.","1 week",[14,18,21,24,27,30,34,37,40,44,47,50,53,57,60,63,66,69,72],{"measure":15,"description":16,"timeFrame":17},"Percentage of patients with a Generalized Pustular Psoriasis Physician Global Assessment(GPPGA) total score of 0 or 1","Percentage of patients with a total Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score of 0 (clear) or 1 (almost clear) at weeks 1 and 4.","1 week and 4 weeks",{"measure":19,"description":20,"timeFrame":17},"Percentage change from baseline in Generalized Pustular Psoriasis Area and Severity Index (GPPASI) total score","Percentage change from baseline in the total score of generalized pustular psoriasis area and severity index (GPPASI) at week 1 and week 4.",{"measure":22,"description":23,"timeFrame":17},"Change from baseline in Generalized Pustular Psoriasis Area and Severity Index(GPPASI) total score","Change from baseline in Generalized Pustular Psoriasis Area and Severity Index(GPPAS) total score at week 1 and week 4. If lower than the baseline score, indicate a certain degree of disease relief; conversely, if higher, it indicates an aggravation of the disease symptoms.",{"measure":25,"description":26,"timeFrame":17},"Percentage of patients with Generalized Pustular Psoriasis Area and Severity Index(GPPASI) 50","Percentage of patients who achieved Generalized Pustular Psoriasis Area and Severity Index(GPPASI) 50 at week 1 and week 4.",{"measure":28,"description":29,"timeFrame":17},"Percentage of patients with Generalized Pustular Psoriasis Area and Severity Index(GPPASI) 75","Percentage of patients who achieved Generalized Pustular Psoriasis Area and Severity Index(GPPASI) 75 at week 1 and week 4",{"measure":31,"description":32,"timeFrame":33},"Percentage of patients with pustule subterm achieving a score of 0","Percentage of patients with Generalized Pustular Psoriasis Physician Global Assessment(GPPGA) pustule subterm achieving a score of 0 (no visible pustules) at week 4.","4 weeks",{"measure":35,"description":36,"timeFrame":33},"Change from baseline in Psoriasis Symptom Scale (PSS) score","Change from baseline in Psoriasis Symptom Scale (PSS) score at week 4",{"measure":38,"description":39,"timeFrame":33},"Change from baseline in disease life quality index (DLQI)","Change from baseline in skin disease life quality index (DLQI) at week 4. If lower than the baseline score, indicate a certain degree of disease relief; conversely, if higher, it indicates an aggravation of the disease symptoms.",{"measure":41,"description":42,"timeFrame":43},"Adverse Drug Event (AE)","Any untoward medical occurrence of a subject following drug treatment or exposure to an experimental factor, whether or not causally related to treatment or exposure.","113 days or 169 days",{"measure":45,"description":46,"timeFrame":43},"Serious Adverse Event (SAE)","An event that occurs in the course of a clinical trial that results in the death of a subject or patient, serious deterioration in health, hospitalization or prolongation of hospitalization, permanent disability or loss of function, or serious consequences such as birth defects or birth defects.",{"measure":48,"description":49,"timeFrame":43},"Treatment-Emergent Adverse Events (TEAES)","Adverse events that occur during treatment, including from the start of treatment to a certain period of time after the end of treatment, may be directly or indirectly related to treatment.",{"measure":51,"description":52,"timeFrame":43},"Abnormal clinical laboratory examination indicators","Any laboratory abnormalities that occur during the test.",{"measure":54,"description":55,"timeFrame":56},"Time of maximum concentration (Tmax)","It refers to the time it takes for the human blood concentration curve to reach the highest concentration (peak concentration) after a single dose, measured in hours or minutes.","1 hour pre-dose on day 1, immediately post dose, 1, 6, 24, 48, 168, 336, 504, 672, 1344, 2016, 2688 hours post dose. Day 8 Immediately after the end of salvage therapy administration, 1, 6, 24, 48 hours post dose",{"measure":58,"description":59,"timeFrame":56},"Maximum Concentration (Cmax)","The highest blood concentration reached after the drug is absorbed in the body.",{"measure":61,"description":62,"timeFrame":56},"Area Under the Curve (AUC)","It refers to the area covered by the concentration of a drug in the blood under the curve of changes over time.",{"measure":64,"description":65,"timeFrame":56},"Apparent Volume of Distribution(Vd\u002FF)","When the drug reaches dynamic equilibrium in the body, the ratio of the amount of drug in the body to the blood concentration is called the apparent volume of distribution.",{"measure":67,"description":68,"timeFrame":56},"Apparent Clearance (CL\u002FF)","The sum of drug clearance rates of liver and kidney, etc.",{"measure":70,"description":71,"timeFrame":56},"Plasma half-life time (t1\u002F2)","The time it takes for the concentration of the drug in the plasma to drop by half.",{"measure":73,"description":74,"timeFrame":75},"Anti-drug antibody (ADA)","Incidence of anti-drug antibodies (ADA) in subjects.","Through study completion, an average of half a year",null,{"allocation":78,"interventionModel":79,"interventionModelDescription":76,"primaryPurpose":80,"observationalModel":76,"timePerspective":76,"maskingInfo":81},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":82,"maskingDescription":76,"whoMasked":83},"QUADRUPLE",[84,85,86,87],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR",[89,95],{"label":90,"type":91,"description":92,"interventionNames":93},"TQH2929 Injections","EXPERIMENTAL","Intravenous infusion, single dose",[94],"Drug: TQH2929 Injections",{"label":96,"type":97,"description":92,"interventionNames":98},"TQH2929 Placebo","PLACEBO_COMPARATOR",[99],"Drug: TQH2929 Placebo",[101,105],{"type":102,"name":90,"description":103,"armGroupLabels":104,"otherNames":76},"DRUG","TQH2929 is a humanized monoclonal antibody that interfering with the signal cascade.",[90],{"type":102,"name":96,"description":106,"armGroupLabels":107,"otherNames":76},"Placebo contains no active substance.",[96],[109],{"name":110,"role":111,"phone":112,"phoneExt":76,"email":113},"Hang Li, Doctor","CONTACT","13693058190","drlihang@126.com",[115,131,143,158,173,184,199,214,229,243,254,265,280,294,309,320,334,349,364,379,394,409,424,434,448,457,472,483,498,509,524,539],{"facility":116,"status":117,"city":118,"state":119,"zip":120,"country":121,"countryCode":122,"cosmosGeoPoint":123,"geoPoint":128,"contacts":129},"Peking University First Hospita","RECRUITING","Beijing","Beijing Municipality","100034","China","CN",{"type":124,"coordinates":125},"Point",[126,127],116.39723,39.9075,{"lat":127,"lon":126},[130],{"name":110,"role":111,"phone":112,"phoneExt":76,"email":113},{"facility":132,"status":133,"city":118,"state":119,"zip":134,"country":121,"countryCode":122,"cosmosGeoPoint":135,"geoPoint":137,"contacts":138},"Peking University Third Hospital","NOT_YET_RECRUITING","100191",{"type":124,"coordinates":136},[126,127],{"lat":127,"lon":126},[139],{"name":140,"role":111,"phone":141,"phoneExt":76,"email":142},"Wenhui Wang, Doctor","156 1190 8751","wwh0608@126.com",{"facility":144,"status":133,"city":145,"state":146,"zip":147,"country":121,"countryCode":122,"cosmosGeoPoint":148,"geoPoint":152,"contacts":153},"The First Affiliated Hospital of Fujian Medical University","Fuzhou","Fujian","350000",{"type":124,"coordinates":149},[150,151],119.30611,26.06139,{"lat":151,"lon":150},[154],{"name":155,"role":111,"phone":156,"phoneExt":76,"email":157},"Niu Xiang, Master","13696834928","408089668@qq.com",{"facility":159,"status":133,"city":160,"state":161,"zip":162,"country":121,"countryCode":122,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"Southern Medical University Dermatology Hospital","Guangzhou","Guangdong","510091",{"type":124,"coordinates":164},[165,166],113.25,23.11667,{"lat":166,"lon":165},[169],{"name":170,"role":111,"phone":171,"phoneExt":76,"email":172},"Bin Yang, Doctor","13922207231","yangbin101@hotmail.com",{"facility":174,"status":133,"city":160,"state":161,"zip":175,"country":121,"countryCode":122,"cosmosGeoPoint":176,"geoPoint":178,"contacts":179},"Sun Yat-sen Memorial Hospital, Sun Yat-sen University","510120",{"type":124,"coordinates":177},[165,166],{"lat":166,"lon":165},[180],{"name":181,"role":111,"phone":182,"phoneExt":76,"email":183},"Zhenrui Shi, Doctor","13908008569","839241987@qq.com",{"facility":185,"status":133,"city":186,"state":187,"zip":188,"country":121,"countryCode":122,"cosmosGeoPoint":189,"geoPoint":193,"contacts":194},"The Affiliated Hospital of Guizhou Medical University","Guiyang","Guizhou","550004",{"type":124,"coordinates":190},[191,192],106.71667,26.58333,{"lat":192,"lon":191},[195],{"name":196,"role":111,"phone":197,"phoneExt":76,"email":198},"Yu Wang, Doctor","13984171241","84343798@qq.com",{"facility":200,"status":133,"city":201,"state":202,"zip":203,"country":121,"countryCode":122,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"The Second Hospital Of Hebei Medical University","Shijiazhuang","Hebei","050000",{"type":124,"coordinates":205},[206,207],114.47861,38.04139,{"lat":207,"lon":206},[210],{"name":211,"role":111,"phone":212,"phoneExt":76,"email":213},"Yanling Li, Master","15130119920","lyldoctor@sina.com",{"facility":215,"status":133,"city":216,"state":217,"zip":218,"country":121,"countryCode":122,"cosmosGeoPoint":219,"geoPoint":223,"contacts":224},"The Second Affiliated Hospital of Henan University of science and technology","Luoyang","Henan","471000",{"type":124,"coordinates":220},[221,222],112.43684,34.67345,{"lat":222,"lon":221},[225],{"name":226,"role":111,"phone":227,"phoneExt":76,"email":228},"Bin Zhang, Bachelor","18637968669","1079378529@qq.com",{"facility":230,"status":133,"city":231,"state":217,"zip":232,"country":121,"countryCode":122,"cosmosGeoPoint":233,"geoPoint":237,"contacts":238},"Zhengzhou Central Hospital","Zhengzhou","450000",{"type":124,"coordinates":234},[235,236],113.64861,34.75778,{"lat":236,"lon":235},[239],{"name":240,"role":111,"phone":241,"phoneExt":76,"email":242},"Yuhong Zhang, Master","15837180902","zyhdyxiang@126.com",{"facility":244,"status":133,"city":231,"state":217,"zip":245,"country":121,"countryCode":122,"cosmosGeoPoint":246,"geoPoint":248,"contacts":249},"Henan Provincial People's Hospital","450003",{"type":124,"coordinates":247},[235,236],{"lat":236,"lon":235},[250],{"name":251,"role":111,"phone":252,"phoneExt":76,"email":253},"Hongwei Liu, Bachelor","18637110289","1831824589@qq.com",{"facility":255,"status":133,"city":231,"state":217,"zip":256,"country":121,"countryCode":122,"cosmosGeoPoint":257,"geoPoint":259,"contacts":260},"The fifth Affiliated hospital of zhengzhou university","450052",{"type":124,"coordinates":258},[235,236],{"lat":236,"lon":235},[261],{"name":262,"role":111,"phone":263,"phoneExt":76,"email":264},"Hongwei Cao, Master","13598867509","zdwfy2223chw@163.com",{"facility":266,"status":133,"city":267,"state":268,"zip":269,"country":121,"countryCode":122,"cosmosGeoPoint":270,"geoPoint":274,"contacts":275},"Shiyan Renmin Hospital","Shiyan","Hubei","442000",{"type":124,"coordinates":271},[272,273],110.77806,32.6475,{"lat":273,"lon":272},[276],{"name":277,"role":111,"phone":278,"phoneExt":76,"email":279},"Zudong Meng, Master","13997837543","1970547910@qq.com",{"facility":281,"status":133,"city":282,"state":268,"zip":283,"country":121,"countryCode":122,"cosmosGeoPoint":284,"geoPoint":288,"contacts":289},"Renmin Hospital of Wuhan University","Wuhan","430060",{"type":124,"coordinates":285},[286,287],114.26667,30.58333,{"lat":287,"lon":286},[290],{"name":291,"role":111,"phone":292,"phoneExt":76,"email":293},"Shan Jiang, Doctor","13659892065","Jiangshan794101@126.com",{"facility":295,"status":133,"city":296,"state":297,"zip":298,"country":121,"countryCode":122,"cosmosGeoPoint":299,"geoPoint":303,"contacts":304},"The First Hospital of Hunan University of Chinese Medicine","Changsha","Hunan","410007",{"type":124,"coordinates":300},[301,302],112.97087,28.19874,{"lat":302,"lon":301},[305],{"name":306,"role":111,"phone":307,"phoneExt":76,"email":308},"Jianyuan Xi, Doctor","15974172722","xijianyuan2010@126.com",{"facility":310,"status":133,"city":296,"state":297,"zip":311,"country":121,"countryCode":122,"cosmosGeoPoint":312,"geoPoint":314,"contacts":315},"Xiangya Hospital of Central South University","410008",{"type":124,"coordinates":313},[301,302],{"lat":302,"lon":301},[316],{"name":317,"role":111,"phone":318,"phoneExt":76,"email":319},"Juan Su, Doctor","15116408921","3694944834@qq.com",{"facility":321,"status":133,"city":322,"state":297,"zip":323,"country":121,"countryCode":122,"cosmosGeoPoint":324,"geoPoint":328,"contacts":329},"The General Hospital Of Hunan University Of Medicine","Huaihua","41800",{"type":124,"coordinates":325},[326,327],110.00404,27.56337,{"lat":327,"lon":326},[330],{"name":331,"role":111,"phone":332,"phoneExt":76,"email":333},"Xuelian Zheng, Master","13307459875","3466098939@qq.com",{"facility":335,"status":133,"city":336,"state":337,"zip":338,"country":121,"countryCode":122,"cosmosGeoPoint":339,"geoPoint":343,"contacts":344},"The first hospital of jilin university","Changchun","Jilin","130012",{"type":124,"coordinates":340},[341,342],125.32278,43.88,{"lat":342,"lon":341},[345],{"name":346,"role":111,"phone":347,"phoneExt":76,"email":348},"Shanshan Li, Doctor","13756661632","shansalee@163.com",{"facility":350,"status":133,"city":351,"state":352,"zip":353,"country":121,"countryCode":122,"cosmosGeoPoint":354,"geoPoint":358,"contacts":359},"The first hospital of china medical university","Shenyang","Liaoning","110001",{"type":124,"coordinates":355},[356,357],123.43278,41.79222,{"lat":357,"lon":356},[360],{"name":361,"role":111,"phone":362,"phoneExt":76,"email":363},"Xinghua Gao, Doctor","13940152467","gaobarry@hotmail.com",{"facility":365,"status":133,"city":366,"state":367,"zip":368,"country":121,"countryCode":122,"cosmosGeoPoint":369,"geoPoint":373,"contacts":374},"Shandong First Medical University Affiliated Dermatology Hospital","Jinan","Shandong","250022",{"type":124,"coordinates":370},[371,372],116.99722,36.66833,{"lat":372,"lon":371},[375],{"name":376,"role":111,"phone":377,"phoneExt":76,"email":378},"Furen Zhang, Doctor","13608921718","zhangfurenlcsy@163.com",{"facility":380,"status":133,"city":381,"state":382,"zip":383,"country":121,"countryCode":122,"cosmosGeoPoint":384,"geoPoint":388,"contacts":389},"Shanghai Skin Disease Hospital","Shanghai","Shanghai Municipality","200443",{"type":124,"coordinates":385},[386,387],121.45806,31.22222,{"lat":387,"lon":386},[390],{"name":391,"role":111,"phone":392,"phoneExt":76,"email":393},"Yangfeng Ding, Doctor","18017336636","dingyangfeng@aliyun.com",{"facility":395,"status":133,"city":396,"state":397,"zip":398,"country":121,"countryCode":122,"cosmosGeoPoint":399,"geoPoint":403,"contacts":404},"The Second Affiliated Hospital of Xi'an Jiaotong University","Xi’an","Shanxi","710061",{"type":124,"coordinates":400},[401,402],113.52486,35.99785,{"lat":402,"lon":401},[405],{"name":406,"role":111,"phone":407,"phoneExt":76,"email":408},"Songmei Geng, Doctor","13060423612","gsm312@yahoo.com",{"facility":410,"status":133,"city":411,"state":412,"zip":413,"country":121,"countryCode":122,"cosmosGeoPoint":414,"geoPoint":418,"contacts":419},"Chengdu Second People's Hospital","Chengdu","Sichuan","610000",{"type":124,"coordinates":415},[416,417],104.06667,30.66667,{"lat":417,"lon":416},[420],{"name":421,"role":111,"phone":422,"phoneExt":76,"email":423},"Yanyan Feng, Doctor","19150169967","Yolanda20220918@163.com",{"facility":425,"status":133,"city":411,"state":412,"zip":413,"country":121,"countryCode":122,"cosmosGeoPoint":426,"geoPoint":428,"contacts":429},"Sichuan Provincial People' s Hospital",{"type":124,"coordinates":427},[416,417],{"lat":417,"lon":416},[430],{"name":431,"role":111,"phone":432,"phoneExt":76,"email":433},"Lixia Zhang, Doctor","17708130396","zhanglixia0310@163.com",{"facility":435,"status":133,"city":436,"state":412,"zip":437,"country":121,"countryCode":122,"cosmosGeoPoint":438,"geoPoint":442,"contacts":443},"The Affiliated Hospital of Southwest Medical University","Luzhou","646000",{"type":124,"coordinates":439},[440,441],105.42575,28.8903,{"lat":441,"lon":440},[444],{"name":445,"role":111,"phone":446,"phoneExt":76,"email":447},"Chengsong He, Master","13700980878","13700980878@163.com",{"facility":435,"status":133,"city":436,"state":412,"zip":437,"country":121,"countryCode":122,"cosmosGeoPoint":449,"geoPoint":451,"contacts":452},{"type":124,"coordinates":450},[440,441],{"lat":441,"lon":440},[453],{"name":454,"role":111,"phone":455,"phoneExt":76,"email":456},"Qing Peng, Doctor","18181873310","qingpeng9712118@163.com",{"facility":458,"status":133,"city":459,"state":460,"zip":461,"country":121,"countryCode":122,"cosmosGeoPoint":462,"geoPoint":466,"contacts":467},"Tianjin Medical University General Hospital","Tianjin","Tianjin Municipality","300052",{"type":124,"coordinates":463},[464,465],117.17667,39.14222,{"lat":465,"lon":464},[468],{"name":469,"role":111,"phone":470,"phoneExt":76,"email":471},"Huiping Wang, Doctor","13702031042","huiping1208@163.com",{"facility":473,"status":133,"city":459,"state":460,"zip":474,"country":121,"countryCode":122,"cosmosGeoPoint":475,"geoPoint":477,"contacts":478},"Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital","300120",{"type":124,"coordinates":476},[464,465],{"lat":465,"lon":464},[479],{"name":480,"role":111,"phone":481,"phoneExt":76,"email":482},"Litao Zhang, Doctor","18602228122","ZhanglitaoYG@163.co",{"facility":484,"status":133,"city":485,"state":486,"zip":487,"country":121,"countryCode":122,"cosmosGeoPoint":488,"geoPoint":492,"contacts":493},"People's Hospital of Xinjiang Uygur Autonomous Region","Ürümqi","Xinjiang","830001",{"type":124,"coordinates":489},[490,491],87.60046,43.80096,{"lat":491,"lon":490},[494],{"name":495,"role":111,"phone":496,"phoneExt":76,"email":497},"Xiaojing Kang, Doctor","13999927999","drkangxj666@163.com",{"facility":499,"status":133,"city":485,"state":486,"zip":500,"country":121,"countryCode":122,"cosmosGeoPoint":501,"geoPoint":503,"contacts":504},"The First Affiliated Hospital of Xinjiang Medical University","830013",{"type":124,"coordinates":502},[490,491],{"lat":491,"lon":490},[505],{"name":506,"role":111,"phone":507,"phoneExt":76,"email":508},"Xuefeng Wan, Doctor","13579867192","xjwanxuefeng@sina.com",{"facility":510,"status":133,"city":511,"state":512,"zip":513,"country":121,"countryCode":122,"cosmosGeoPoint":514,"geoPoint":518,"contacts":519},"The First Affiliated Hospital of Kunming Medical University","Kunming","Yunnan","650032",{"type":124,"coordinates":515},[516,517],102.71833,25.03889,{"lat":517,"lon":516},[520],{"name":521,"role":111,"phone":522,"phoneExt":76,"email":523},"Ying Tu, Doctor","13608711764","747307239@qq.com",{"facility":525,"status":133,"city":526,"state":527,"zip":528,"country":121,"countryCode":122,"cosmosGeoPoint":529,"geoPoint":533,"contacts":534},"Jiaxing First Hospital","Jiaxing","Zhejiang","314001",{"type":124,"coordinates":530},[531,532],120.75,30.7522,{"lat":532,"lon":531},[535],{"name":536,"role":111,"phone":537,"phoneExt":76,"email":538},"Wuhao Yin, Master","13957323606","whyin69@sina.com",{"facility":540,"status":133,"city":541,"state":527,"zip":542,"country":121,"countryCode":122,"cosmosGeoPoint":543,"geoPoint":547,"contacts":548},"The first affiliated hospital of ningbo university","Ningbo","315020",{"type":124,"coordinates":544},[545,546],121.54945,29.87819,{"lat":546,"lon":545},[549],{"name":550,"role":111,"phone":551,"phoneExt":76,"email":552},"Bingjiang Lin, Master","17757461212","linbingj@163.com",{"type":554,"investigatorFullName":76,"investigatorTitle":76,"investigatorAffiliation":76,"oldNameTitle":76,"oldOrganization":76},"SPONSOR","100617087",false,"NCT07314060","A Clinical Trial of TQH2929 Injection in Patients With Acute Flare-up of Generalized Pustular Psoriasis","A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Clinical Trial Evaluating the Efficacy and Safety of TQH2929 Injection in Patients With Acute Exacerbations of Generalized Pustular Psoriasis","Inclusion Criteria:\n\n* Age ≥ 18 or ≤75 years old at screening, regardless of gender;\n* Meet the diagnostic criteria defined by the 2017 European Society for Clinical Nutrition and Metabolism (ESPEN) Research Workshop (ERASPEN) consensus and be diagnosed as （generalized pustular psoriasis(GPP);\n* Compliant with GPP acute onset;\n* Able to read and understand, and willing to sign the informed consent form;\n* Willing and compliant with study visits and related procedures;\n* Female subjects of childbearing age should agree that contraceptive measures must be used during the study and for 6 months after the end of the study;\n\nExclusion Criteria:\n\n* Pustules are limited to psoriasis vulgaris on psoriasis plaques;\n* Concomitant skin disease or medical disease that may interfere with the investigator's evaluation of the subject's treatment response;\n* Presence of severe, progressive, or uncontrolled disease, or signs and symptoms that are not suitable for participation in the investigator, in the judgment of the investigator:\n* Serum virological abnormalities during the screening period;\n* Chest radiology examination shows that the subject has active tuberculosis or a history of contact with open tuberculosis subjects in the past 6 months or a positive Interferon-Gamma Release Assays(IGRA) test;\n* History of serious infection leading to hospitalization within 2 months prior to baseline;\n* Active infection requiring systemic antibiotics, systemic antifungals, or systemic antiviral therapy within 2 weeks prior to baseline, according to the investigator's assessment;\n* History of opportunistic infection within 6 months prior to baseline;\n* Received live (attenuated) vaccine treatment within 12 weeks prior to baseline;\n* Any major surgery within 4 weeks prior to baseline or planned major surgery during the study;\n* Received blood transfusion within 4 weeks prior to baseline;\n* Participated in clinical trials of other drugs or medical devices within 4 weeks before baseline;\n* Any known or suspected congenital or acquired immunodeficiency state or condition that may compromise the subject's immune status;\n* Subjects with any type of active malignancy or a history of malignancy;\n* Alcohol, drug and known drug dependence;\n* Pregnant or lactating women;\n* Subjects cannot tolerate intravenous infusion administration.","ALL","18 Years","75 Years",{"count":565,"type":566},36,"ESTIMATED","INTERVENTIONAL",[569],"PHASE2","This is a multicenter, randomized, double-blind, placebo-controlled phase II clinical study, all subjects need to use TQH2929 injection\u002Fplacebo. The aim was to demonstrate the efficacy and safety of TQH2929 injection in patients with acute exacerbations of generalized pustular psoriasis, with a total of 36 subjects.",[572],"Generalized Pustular Psoriasis","2026-03-20",{"date":575,"type":576},"2026-03-24","ACTUAL",{"date":578,"type":576},"2026-03-19",{"date":580,"type":566},"2027-07",{"name":5,"class":6},32]