[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555926":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":34,"responsibleParty":49,"collaborators":30,"id":52,"slug":30,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":30,"enrollmentInfo":61,"targetDuration":30,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":30,"overallStatus":36,"whyStopped":30,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Medical Center Groningen","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cannabis oil","EXPERIMENTAL","Treatment with cannabis oil",[13],"Drug: Medical Cannabis",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Medical Cannabis","Medical cannabis oil three times daily",[9],[21],"Cannabis oil containing 10% delta-9-tetrahydrocannabinol (THC) and 5% cannabidiol (CBD)",[23],{"name":24,"affiliation":5,"role":25},"M W Nijkamp, MD PhD","PRINCIPAL_INVESTIGATOR",[27,32],{"name":24,"role":28,"phone":29,"phoneExt":30,"email":31},"CONTACT","+31625649985",null,"m.w.nijkamp@umcg.nl",{"name":33,"role":28,"phone":30,"phoneExt":30,"email":30},"DJ A de Groot, MD PhD",[35],{"facility":5,"status":36,"city":37,"state":30,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Groningen","9713 GZ","Netherlands",{"type":41,"coordinates":42},"Point",[43,44],6.56667,53.21917,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":29,"phoneExt":30,"email":31},"Maarten W Nijkamp, MD PhD",{"type":25,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Maarten Nijkamp","Principal Investigator","100555926",false,"NCT06518434","A Pilot Study on the Effect of Cannabis Oil in Untreatable Liver Cancer Patients","A Phase 2a Study on the Anti-tumoral Effect of Cannabis Oil (THC 10% \u002F CBD 5%) in Patients With Advanced Untreatable Hepatocellular Carcinoma","CanHep","Inclusion Criteria:\n\n* Age =\\>18 yrs\n* Histologically proven hepatocellular carcinoma\n* Non-cirrhosis or Child Pugh A cirrhosis\n* Hepatic encephalopathy grade 0 or 1\n* Multidisciplinary treatment (MDT)-advised best supportive care for untreatable advanced HCC or patients unable to undergo or declining treatment for advanced HCC.\n* Minimal life expectancy of 3 months\n* Willing and able to attend follow-up examinations\n* Willing to stop active traffic participation or controlling machinery during the study period if applicable\n* Signed informed consent\n* Language: Dutch or English\n\nExclusion Criteria:\n\n* Child Pugh B or C cirrhosis\n* Hepatic encephalopathy grade 2 or more\n* Previous systemic treatment for HCC\n* Mental conditions rendering the subject incapable to understand the nature, scope and consequences of the trial\n* Use of medicinal cannabis for other purposes\n* Contra-indications for medicinal cannabis oil:\n\n  * Patients who have experienced a myocardial infarction or clinically significant cardiac dysfunction within the last 12 months or have had a cardiac disorder that, in the opinion of the investigator would have put the participant at risk of a clinically significant arrhythmia or myocardial infarction.\n  * Patients with known psychotic disorders\n  * Female patients who are pregnant or lactating\n  * Patients (men or women) intending to start a family\n  * Hypersensitivity to cannabinoids or any of the excipients of the cannabis oil","ALL","18 Years",{"count":62,"type":63},20,"ESTIMATED","INTERVENTIONAL",[66],"PHASE2","to study the anti-tumor effect of cannabis oil (THC10% \u002F CBD5%) in untreatable HCC patients based on mRECIST and RECIST criteria",[69,70],"Hepatocellular Carcinoma","Cannabis","2024-07-23",{"date":73,"type":74},"2024-07-24","ACTUAL",{"date":76,"type":74},"2021-04-15",{"date":78,"type":63},"2027-04-15",{"name":5,"class":6},1]