[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100356129":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":43,"responsibleParty":61,"collaborators":63,"id":66,"slug":25,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Genesis Athens Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants receiving PRP treatment","EXPERIMENTAL","Menopausal women minimum 45 years of age, receiving ovarian PRP treatment.",[13],"Biological: Autologous PRP intra ovarian infusion",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group: Participants receiving Platelet Free Plasma","PLACEBO_COMPARATOR","Women in menopause, 45-55 years old, treated with autologous PFP intra ovarian infusion.",[19],"Biological: Autologous PFP intra ovarian infusion",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"BIOLOGICAL","Autologous PRP intra ovarian infusion",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Autologous PFP intra ovarian infusion",[15],[30],{"name":31,"affiliation":32,"role":33},"Agni Pantou, MD","Centre of Human Reproduction, Genesis Athens Clinic","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Mara Simopoulou, PhD","CONTACT","+306979234100","marasimopoulou@hotmail.com",{"name":31,"role":37,"phone":41,"phoneExt":25,"email":42},"+306974447702","agni.pantou@genesisathens.gr",[44],{"facility":45,"status":46,"city":47,"state":25,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Genesis AC","RECRUITING","Athens","15232","Greece",{"type":51,"coordinates":52},"Point",[53,54],23.72784,37.98376,{"lat":54,"lon":53},[57,58,59],{"name":31,"role":37,"phone":25,"phoneExt":25,"email":42},{"name":31,"role":33,"phone":25,"phoneExt":25,"email":25},{"name":60,"role":33,"phone":25,"phoneExt":25,"email":25},"Konstantinos Pantos, MD,PhD",{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[64],{"name":65,"class":6},"National and Kapodistrian University of Athens","100356129",false,"NCT03916978","Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women","Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in Menopausal Women","PRP","Inclusion Criteria:\n\n* Age between 45-55 years old\n* Amenorrhea for at least 12 months\n* Discontinuation of any complementary\u002Fadjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.\n* Willing to comply with study requirements\n\nExclusion Criteria:\n\n* Any pathological disorder related to reproductive system anatomy\n* Previous POI diagnosis\n* Abnormal karyotype\n* Endometriosis\n* Adenomyosis\n* Fibroids and adhesions\n* Infections in reproductive system\n* Current or previous diagnosis of reproductive system cancer\n* History of familiar cancer in reproductive system\n* Severe male factor infertility\n* Prior referral for PGT\n* Ovarian inaccessibility\n* Endocrinological disorders (Hypothalamus-Pituitary disorders, thyroid dysfunction, diabetes mellitus, metabolic syndrome)\n* BMI\\>30 kg\u002Fm2 or BMI\\\u003C18.5 kg\u002Fm2\n* Systematic autoimmune disorders",true,"FEMALE","45 Years","55 Years",{"count":78,"type":79},100,"ESTIMATED","INTERVENTIONAL",[82,83],"PHASE2","PHASE3","Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.",[86,87,88,89],"Infertility, Female","Anovulatory Infertility","Menopause","Amenorrhea",[91,92],"Ovarian rejuvenation","Ovarian reactivation; ovulation","2024-12-20",{"date":95,"type":96},"2024-12-27","ACTUAL",{"date":98,"type":96},"2019-05-21",{"date":100,"type":79},"2026-07-30",{"name":5,"class":6},1]