Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age75+
SponsorJian Chen
About this trial
To observe the effect and toxicity of carbon ion radiotherapy on local advanced non-small cell lung cancer over 75 years old patients. Systemic therapy could be targeted therapy, chemotherapy or immunotherapy.
Eligibility criteria
Qualifiers
Older than 75 years old.
ECOG general status score of 0-2.
Primary non-small cell lung cancer (NSCLC) confirmed by histology or cytological pathology, T1-4N1-3M0, stage IIb-IIIc (AJCC/UICC 8th edition).
Medically inoperable, or patient refuses surgery.
Disqualifiers
Patient with squamous cell carcinoma was treated with bevacizumab before carbon ion radiotherapy.
Complicated with other malignant tumors that have not been controlled.
Patient whose particle radiotherapy plan cannot meet the minimum target dose coverage and dose volume limitation requirements, or cannot meet the dose constrains of normal tissue or organs.
Chest radiation therapy or radioactive particle implantation history.
Trial design
Treatments tested in this trial
- carbon ion radiotherapy
- targeted therapy
- single regimen chemotherapy in sequence with radiotherapy
Treatment groups
29 Participants
are divided into 1 treatment groupLocations
1Shanghai Proton and Heavy Ion Center201513, ShanghaiShanghai Municipality, China
Sponsors and collaborators
Jian Chen
Lead sponsor
Shanghai Proton and Heavy Ion Center
Sponsor institution
Source ClinicalTrials.gov