[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546926":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":49,"responsibleParty":78,"collaborators":81,"id":92,"slug":47,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":93,"sex":99,"minAge":100,"maxAge":47,"enrollmentInfo":101,"targetDuration":47,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":52,"whyStopped":47,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},{"fullName":5,"class":6},"Université du Québec à Trois-Rivières","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Saline Injection","EXPERIMENTAL","A single injection of saline solution",[13],"Drug: Saline Solution (NaCl 0,9%)",{"label":15,"type":16,"description":17,"interventionNames":18},"Corticosteroid Injection","ACTIVE_COMPARATOR","Usual care, consisting on a single injection of corticosteroids",[19],"Drug: Triamcinolone Acetonide",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Saline Solution (NaCl 0,9%)","Ultrasound\u002Ffluoroscopy-guided intra-articular injection of 0.25ml of 0.9% saline solution.",[9],[27],"Saline solution",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Triamcinolone Acetonide","Ultrasound-guided intra-articular injection 0.25ml (10 mg) of triamcinolone.",[15],[33],"Corticosteroid",[35],{"name":36,"affiliation":5,"role":37},"Tokiko Hamasaki, PhD","PRINCIPAL_INVESTIGATOR",[39,44],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","819-478-5011","2903","tokiko.hamasaki@uqtr.ca",{"name":45,"role":40,"phone":46,"phoneExt":47,"email":48},"Carlos Gevers-Montoro, PhD","819-979-0448",null,"carlos.geversmontoro@mcgill.ca",[50,68],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Centre Hospitalier de l'Université de Montréal - Physiatry","RECRUITING","Montreal","Quebec","H2W 1T6","Canada",{"type":58,"coordinates":59},"Point",[60,61],-73.58781,45.50884,{"lat":61,"lon":60},[64],{"name":65,"role":40,"phone":66,"phoneExt":47,"email":67},"Dr Luong","514-890-8000","dien-hung.luong.med@ssss.gouv.qc.ca",{"facility":69,"status":52,"city":53,"state":54,"zip":70,"country":56,"cosmosGeoPoint":71,"geoPoint":73,"contacts":74},"Centre Hospitalier de l'Université de Montréal - Chirurgie plastique","H2X 0C1",{"type":58,"coordinates":72},[60,61],{"lat":61,"lon":60},[75],{"name":76,"role":40,"phone":66,"phoneExt":47,"email":77},"Dr Harris","patrick.harris.med@ssss.gouv.qc.ca",{"type":37,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"Tokiko Hamasaki","Assistant Professor",[82,84,86,88,90],{"name":83,"class":6},"Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal",{"name":85,"class":6},"McGill University",{"name":87,"class":6},"Université de Montréal",{"name":89,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)",{"name":91,"class":6},"Centre de Recherche du Centre Hospitalier de l'Université de Montréal","100546926",false,"NCT06401317","Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)","Comparison of the Efficacy of Intra-Articular Corticosteroid Injections Versus Saline Solution for Thumb Osteoarthritis: Double-Blind Pragmatic Randomized Pilot Study","CASITOA","Inclusion Criteria:\n\n* aged ≥18 years;\n* diagnosis of TMO was confirmed by X-ray interpreted by a radiologist;\n* suffering from pain at the base of the thumb;\n* the attending physician deems that an intra-articular corticosteroid injection would be beneficial, rather than opting for other types of intervention such as surgery\n* can read, understand and answer in either French or English.\n\nExclusion Criteria:\n\n* having received one or more corticosteroid injections in the last 12 months or surgery on the affected thumb;\n* suffering from painful thumb caused by a trauma (e.g., fracture, sprain), rheumatoid arthritis, or De Quervain's tendonitis; and\n* being pregnant or breastfeeding; and\n* known allergies to any components of the solutions (triamcinolone acetonide, benzyl alcohol, carboxymethylcellulose sodium, hydrochloric acid, polysorbate, sodium chloride, or sodium hydroxide) or to iodinated contrast media.","ALL","18 Years",{"count":102,"type":103},40,"ESTIMATED","INTERVENTIONAL",[106],"PHASE2","Thumb osteoarthritis or trapeziometacarpal osteoarthritis (TMO) is a common and painful form of hand arthritis that limits thumb mobility and hand function, affecting patients' quality of life. Although corticosteroids injections are a typical treatment, their effectiveness has been challenged, and side effects have been reported. Recent studies suggest that saline injections, usually considered inactive, might be a viable treatment option. The primary goal of this study is to compare the effectiveness of saline injections versus corticosteroids injections in reducing TMO-related pain and improving hand function. In this study, 40 people with TMO will be randomly assigned to receive either a corticosteroids or a saline injection, without them or the doctors performing the injection knowing which one was administered (double blind). If saline injections prove more effective, they could provide a less harmful and cheaper therapeutic alternative for TMO patients.",[109],"Trapeziometacarpal Osteoarthritis",[111,112,113,114,115,116,117,118],"Corticosteroids","Feasibility","Blinding","Randomized controlled trial","Saline","Trapeziometacarpal osteoarthritis","Intra-articular injection","Pragmatic trial","2026-01-20",{"date":121,"type":122},"2026-01-22","ACTUAL",{"date":124,"type":122},"2025-11-04",{"date":126,"type":103},"2028-12-31",{"name":5,"class":6},2]