[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528795":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":34,"responsibleParty":53,"collaborators":56,"id":59,"slug":11,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":11,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":11,"enrollmentInfo":67,"targetDuration":11,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":11,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Stony Brook University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"SBRT to the spine","EXPERIMENTAL",null,[13],"Radiation: SBRT to the spine",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":11},"RADIATION","Stereotactic body radiation therapy (SBRT) administered to spine metastases",[9],[20],{"name":21,"affiliation":22,"role":23},"Kartik Mani, MD PhD","Stony Brook Cancer Center","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":11,"email":29},"Hermina Munoz, RN","CONTACT","631-216-2990","hermina.munoz@stonybrookmedicine.edu",{"name":31,"role":27,"phone":32,"phoneExt":11,"email":33},"Lucia Joya","631-216-2998","lucia.joya@stonybrookmedicine.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Stony Brook University Hospital","RECRUITING","Stony Brook","New York","11794","United States",{"type":43,"coordinates":44},"Point",[45,46],-73.14094,40.92565,{"lat":46,"lon":45},[49],{"name":50,"role":27,"phone":51,"phoneExt":11,"email":52},"Caterina Vacchi-Suzzi, PhD","631-216-2993","caterina.vacchi-suzzi@stonybrookmedicine.edu",{"type":23,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Kartik Mani","Assistant Professor of Medicine",[57],{"name":58,"class":6},"The University of Texas Health Science Center at San Antonio","100528795",false,"NCT06165419","Definitive Radiation for High-Risk Spine Metastases","A Phase II Study Evaluating Definitive Radiosurgical Decompression in Patients With High-Risk Spinal Metastases","Eligible patients must have:\n\n* Any pathologically proven solid tumor diagnosis not of central nervous system origin with radiographic or pathologic evidence of metastatic disease\n* Metastatic spine involvement documented by imaging\n* Involvement of maximum 3 contiguous vertebral bodies at the index site\n* Intact neurologic function, or only minor neurologic deficits with muscle strength greater or equal to 4 out of 5 with or without steroids\n* An evaluation by an radiation oncology and orthopedic spine\u002Fneurosurgery attending\n* ECOG Performance Status of 0-3\n\nPatients are ineligible if they have:\n\n* An unstable spine defined as a Spinal Instability Neoplastic Score (SINS) greater than 12\n* Had previous surgery or radiation to address the target spinal metastases\n* Radiosensitive tumors (e.g. small cell lung cancer, lymphoma, multiple myeloma, and germ-cell tumors)","ALL","18 Years",{"count":68,"type":69},26,"ESTIMATED","INTERVENTIONAL",[72],"PHASE2","This study is looking at whether patients with cancer that has aggressively spread to the spine can be treated with stereotactic body radiation therapy only and avoid a large spine surgery",[75,76,77,78,79,80,81,82],"Metastatic Cancer","Metastatic Lung Cancer","Metastatic Breast Cancer","Metastatic Tumor","Metastatic Tumor of Bone","Metastatic Tumor to the Spine","Spine Metastases","Metastasis","2025-05-09",{"date":85,"type":86},"2025-05-14","ACTUAL",{"date":88,"type":86},"2023-12-14",{"date":90,"type":69},"2026-05-31",{"name":5,"class":6},1]