[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633167":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":27,"centralContacts":37,"locations":47,"responsibleParty":84,"collaborators":88,"id":92,"slug":27,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":27,"eligibilityCriteria":97,"healthyVolunteers":93,"sex":98,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":27,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":114,"whyStopped":27,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Lifei Qingchang Granules","EXPERIMENTAL","Participants in this arm will receive Lifei Qingchang Granules combined with postural drainage. The granules are administered orally, 1 sachet each time, 3 times a day , for a total duration of 3 months.",[13,14],"Drug: Lifei Qingchang Granules","Procedure: Postural Drainage",{"label":16,"type":17,"description":18,"interventionNames":19},"Placebo Comparator: Placebo","PLACEBO_COMPARATOR","Participants in this arm will receive a matching placebo combined with postural drainage. The placebo is administered orally, 1 sachet each time, 3 times a day , for a total duration of 3 months.",[20,14],"Other: Placebo",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Lifei Qingchang Granules","A Traditional Chinese Medicine in-hospital preparation (Patent No.: ZL202110246137.5). Administered orally, 1 sachet per dose, 3 doses per day for 3 months.",[9],null,{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"Placebo","An inactive matching placebo primarily composed of dextrin, lactose, edible essence, and food coloring. Administered orally, 1 sachet per dose, 3 doses per day for 3 months.",[16],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":27},"PROCEDURE","Postural Drainage","Standardized postural drainage therapy to assist in sputum clearance.",[9,16],[38,43],{"name":39,"role":40,"phone":41,"phoneExt":27,"email":42},"Zhimin Zhang, MD","CONTACT","86-18928868345","zhangzhimin51666@163.com",{"name":44,"role":40,"phone":45,"phoneExt":27,"email":46},"Ran Lin, MD","86-18813751030","r2013051152@163.com",[48,65,73],{"facility":49,"status":27,"city":50,"state":51,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"The Third Affiliated Hospital of Guangzhou Medical University","Guangzhou","Guangdong","510150","China",{"type":55,"coordinates":56},"Point",[57,58],113.25,23.11667,{"lat":58,"lon":57},[61],{"name":62,"role":40,"phone":63,"phoneExt":27,"email":64},"Liping Wei, MD","86-13650858667","weilp8@hotmail.com",{"facility":5,"status":27,"city":50,"state":51,"zip":66,"country":53,"cosmosGeoPoint":67,"geoPoint":69,"contacts":70},"510170",{"type":55,"coordinates":68},[57,58],{"lat":58,"lon":57},[71,72],{"name":39,"role":40,"phone":41,"phoneExt":27,"email":42},{"name":44,"role":40,"phone":45,"phoneExt":27,"email":46},{"facility":74,"status":27,"city":50,"state":51,"zip":75,"country":53,"cosmosGeoPoint":76,"geoPoint":78,"contacts":79},"The Second Affiliated Hospital of Guangzhou Medical University","510260",{"type":55,"coordinates":77},[57,58],{"lat":58,"lon":57},[80],{"name":81,"role":40,"phone":82,"phoneExt":27,"email":83},"Peng Pang, MD","86-15099960366","pangpeng@gzhmu.edu.cn",{"type":85,"investigatorFullName":86,"investigatorTitle":87,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Zhang Zhimin","Professor",[89,91],{"name":90,"class":6},"Second Affiliated Hospital of Guangzhou Medical University",{"name":49,"class":6},"100633167",false,"NCT07523165","Efficacy and Safety of Lifei Qingchang Granules for Stable Bronchiectasis","A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study on the Efficacy and Safety of Lifei Qingchang Granules for Stable Bronchiectasis","Inclusion Criteria:\n\n* Aged 18 to 75 years old, regardless of sex.\n* Diagnosed with bronchiectasis confirmed by High-Resolution Computed Tomography (HRCT) scan.\n* Bronchiectasis is currently in the stable phase.\n* Experienced at least one acute exacerbation of bronchiectasis within the previous 12 months.\n* Diagnosed with the Traditional Chinese Medicine (TCM) syndrome of \"Phlegm-Heat Obstructing the Lungs\".\n* Able to understand the study protocol and voluntarily sign the informed consent form.\n\nExclusion Criteria:\n\n* Allergic to any ingredients of the investigational drug or placebo.\n* Comorbid with other severe systemic diseases (e.g., coronary heart disease, stroke, severe hypertension \\[systolic BP ≥ 180 mmHg or diastolic BP ≥ 110 mmHg\\], active gastric ulcer, uncontrolled diabetes \\[fasting venous blood glucose ≥ 10 mmol\u002FL\\], malignant tumors, abnormal liver or kidney function \\[AST, ALT, or GGT \\> 2 times the upper limit of normal; or serum creatinine \\> 2 times the upper limit of normal\\]) or psychiatric disorders.\n* Comorbid with asthma, allergic bronchopulmonary aspergillosis (ABPA), or active pulmonary tuberculosis.\n* Comorbid with chronic obstructive pulmonary disease (COPD) and presenting COPD as the primary clinical manifestation (as judged by the investigator).\n* Use of inhaled, oral, or intravenous antibiotics within 4 weeks prior to enrollment.\n* Type 2 respiratory failure requiring long-term non-invasive mechanical ventilation or oxygen therapy (\\> 10 hours\u002Fday).\n* History of drug abuse, psychotropic drug dependence, or alcohol abuse.\n* Current smokers or those unable to stop smoking during the study.\n* Pregnant or lactating women, planning to become pregnant during the study, or refusing to use reliable contraceptive methods throughout the study period.\n* Participation in any other clinical trials within 3 months prior to enrollment.\n* Considered unsuitable for participation in this clinical study by the investigator.","ALL","18 Years","75 Years",{"count":102,"type":103},150,"ESTIMATED","INTERVENTIONAL",[106],"PHASE2","The purpose of this study is to evaluate the efficacy and safety of Lifei Qingchang Granules in the treatment of patients with stable bronchiectasis. This is a multicenter, randomized, double-blind, placebo-controlled clinical trial.\n\nResearchers plan to enroll a total of 150 adult participants (aged 18-75) who have been diagnosed with stable bronchiectasis and experience at least one acute exacerbation in the past 12 months. Participants will be randomly assigned into two groups in a 1:1 ratio:\n\n* The treatment group will receive Lifei Qingchang Granules along with standard postural drainage therapy.\n* The control group will receive a matching placebo along with standard postural drainage therapy.\n\nThe treatment period will last for 3 months. The main goal is to see if the treatment can improve patients' respiratory symptoms and overall quality of life.",[109],"Bronchiectasis",[111,112,113,24,34],"Stable Bronchiectasis","Traditional Chinese Medicine","Phlegm-Heat Syndrome","NOT_YET_RECRUITING","2026-04-04",{"date":117,"type":118},"2026-04-13","ACTUAL",{"date":120,"type":103},"2026-04",{"date":122,"type":103},"2028-04",{"name":5,"class":6},3]