Health Trials

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

ConditionsHypertensionUncontrolled Hypertension
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorVanda Pharmaceuticals

About this trial

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

Eligibility criteria

Qualifiers

SiSBP >/= 130 mmHg despite >8 weeks treatment w/ 1 or more antihypertensive therapies

Disqualifiers

Confirmed Grade 3/severe hypertension (SiSBP >/= 180 mmHg, SiDBP >/= 120 mmHg), unstable cardiac disease, renal insufficiency

Trial design

Treatments tested in this trial

  • iloperidone
  • Placebo

Treatment groups

240 Participants
are divided into 2 treatment groups

Locations

28
Arizona
Vanda Investigative Site85053, Phoenix United States
Vanda Investigative Site85281, Tempe United States
Vanda Investigative Site85715, Tucson United States
California
Vanda Investigative Site91910, Chula Vista United States

Sponsors and collaborators

Vanda Pharmaceuticals

Lead sponsor

Source ClinicalTrials.gov