About this trial
The purpose of the prospective, open, randomized controlled, multicenter, exploratory clinical study is to evaluate efficacy and safety of NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus NALIRIFOX for Conversion Therapy for Locally Advanced Pancreatic Cancer
Eligibility criteria
Qualifiers
Histologically or cytologically confi rmed pancreatic cancer;
ECOG performance no more than 1;
Radiographically assessed as locally advanced pancreatic cancer according ;
No previous anti-tumor therapy;
Disqualifiers
Prior anti-tumor therapy of any kind;
Known to be symptomatic central nervous system metastasis and/or cancerous meningitis.
Patients with autoimmune disease or immune deficiency who are treated with immuno-suppressive drugs;
Patients with bleeding tendency;
Trial design
Treatments tested in this trial
- Nal-lRl+Oxaliplain+5- FU +PD 1
- Nal-lRl+Oxaliplain+5- FU
Treatment groups
Locations
Sponsors and collaborators
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Lead sponsor