About this trial

The goal of this study is to learn how a supplement Quercetin can affect microvascular function.

Participants will:

* give two blood draws of 5 mL each * have a camera placed under the tongue to take pictures of blood vessels * have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion

Researchers will compare blood vessel function of those who take estrogen supplements to those who do not.

Eligibility criteria

Qualifiers

Obesity (BMI>30)

Aged 18-40 years

English Speaking

Disqualifiers

BMI>60

Resting SBP ≥180 mmHg or DBP ≥ 110mmHg

Pregnancy or breastfeeding.

Prior history of myocardial infarction

Trial design

Treatments tested in this trial

  • Quercetin (dietary supplement)
  • Placebo

Treatment groups

40 Participants
are divided into 2 treatment groups

Locations

1
Froedtert Hospital53226, WauwatosaWisconsin, United States

Sponsors and collaborators

Medical College of Wisconsin

Lead sponsor