[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100501340":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":30,"responsibleParty":45,"collaborators":11,"id":49,"slug":11,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":11,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":11,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":11,"overallStatus":68,"whyStopped":11,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Shanghai Proton and Heavy Ion Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"carbon ion therapy for unresectable local recurrent rectal cancer","EXPERIMENTAL",null,[13],"Radiation: Carbon ion radiation therapy DT: 74Gy\u002F20 fractions",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"RADIATION","Carbon ion radiation therapy DT: 74Gy\u002F20 fractions","patients with unresectable local recurrent rectal cancer will be treated with carbon ion radiation therapy as re-irradiation",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Xin Cai, Doctor","CONTACT","+86 13901601072","xin.cai@sphic.org.cn",{"name":27,"role":23,"phone":28,"phoneExt":11,"email":29},"Zheng Wang, Doctor","+86 021-38296666","zheng.wang@sphic.org.cn",[31],{"facility":32,"status":11,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Shanghai Proton and Heavy ion center","Shanghai","Pudong","201321","China",{"type":38,"coordinates":39},"Point",[40,41],121.45806,31.22222,{"lat":41,"lon":40},[44],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Xin Cai","Deputy chief physician","100501340",false,"NCT05807984","Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion","A Prospective Phase II Clinical Study of Carbon Ion Re-irradiation in Unresectable Locally Recurrent Rectal Cancer","Inclusion Criteria:\n\n* 1\\) pathologically confirmed rectal adenocarcinoma (including mucinous adenocarcinoma and signet-ring cell carcinoma) and LRRC confirmed by biopsy or clinical diagnosis,\n* 2\\) received a radical operation for their primary tumor and regional lymph nodes,\n* 3\\) received chemo-radiation or radiation in pelvic before CIRT,\n* 4\\) received re-irradiation by CIRT after their pelvic radiotherapy.\n\nExclusion Criteria:\n\n* 1\\) received more than once prior radiotherapy in the same treatment field,\n* 2\\) time to the last radiotherapy was \\\u003C1 year,\n* 3\\) space between the lesion to organ at risk (OARs) (bladder or digestive tract) was too close (\\\u003C5 mm).","ALL","18 Years","80 Years",{"count":59,"type":60},31,"ESTIMATED","INTERVENTIONAL",[63],"PHASE2","Prospective phase II clinical study aim to explore the clinical outcome of patients with unresectable locally recurrent rectal cancer (LRRC) treated with re-irradiation by carbon ion radiotherapy (CIRT)",[66,67],"Rectal Cancer","Recurrent","NOT_YET_RECRUITING","2023-04-07",{"date":71,"type":72},"2023-04-11","ACTUAL",{"date":74,"type":60},"2023-05-01",{"date":76,"type":60},"2026-12-31",{"name":47,"class":6},1]