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and deflation for 5 minutes",[13],"Device: Remote ischemic preconditioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham remote ischemic preconditioning","SHAM_COMPARATOR","3 cycles of blood pressure cuff inflations to non-occlusive pressure of 60 mmHg for 5 minutes and deflation for 5 minutes (Control)",[19],"Device: Sham remote ischemic conditioning",[21,26],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"DEVICE",[9],[25],"RIPC",{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":29},"Sham remote ischemic conditioning",[15],[30],"Sham-RIPC",[32],{"name":33,"affiliation":34,"role":35},"Oladipupo Olafiranye, MD MS","VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","(214) 857-2923",null,"Oladipupo.Olafiranye@va.gov",[43,61,73],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA","RECRUITING","Pittsburgh","Pennsylvania","15240","United States",{"type":51,"coordinates":52},"Point",[53,54],-79.99589,40.44062,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":59,"phoneExt":40,"email":60},"Ning Feng","412-360-6191","ning.feng@va.gov",{"facility":34,"status":45,"city":62,"state":63,"zip":64,"country":49,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Dallas","Texas","75216-7167",{"type":51,"coordinates":66},[67,68],-96.80667,32.78306,{"lat":68,"lon":67},[71,72],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},{"name":33,"role":35,"phone":40,"phoneExt":40,"email":40},{"facility":74,"status":45,"city":75,"state":76,"zip":77,"country":49,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Hunter Holmes McGuire VA Medical Center, Richmond, VA","Richmond","Virginia","23249-0001",{"type":51,"coordinates":79},[80,81],-77.46026,37.55376,{"lat":81,"lon":80},[84],{"name":85,"role":38,"phone":86,"phoneExt":40,"email":87},"Ion Jovin","804-675-5419","ion.jovin@va.gov",{"type":89,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR","100437910",false,"NCT04982419","Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial","RICH","Inclusion Criteria:\n\n* Age 18 years\n* Diagnosis of heart failure with reduced LVEF \\\u003C50%\n* Pre-procedure intravenous normal saline fluid restriction status\n* Society for Cardiovascular Angiography and Interventions (SCAI) AKI risk score (\\>1%)\n* Referral for coronary angiogram and\u002For PCI\n* Suspected stable coronary artery disease or acute coronary syndrome\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* Unstable BP (SBP \\> 200 or \\\u003C80 mmHg) at the time of enrolment\n* Upper limb peripheral arterial disease\n* Unavailability of at least one arm for RIPC\u002FSham-RIPC application\n* Kidney transplant\n* Renal disease requiring dialysis\n* Prior exposure to contrast media within 72hrs preceding coronary angiography\n* Pregnancy\n* Prisoner","ALL","18 Years",{"count":99,"type":100},240,"ESTIMATED","INTERVENTIONAL",[103,104],"PHASE2","PHASE3","This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure undergoing cardiac catheterization and\u002For percutaneous coronary intervention.",[107,108,109,110,111],"Acute Kidney Injury","Heart Failure","Contrast Induced Nephropathy","Coronary Angiography","Percutaneous Coronary Intervention",[113,114,115,116,117,118,119,120,121,122,123],"Contrast-induced acute kidney injury","Congestive heart failure","Contrast induced nephropathy","Coronary angiography","Percutaneous coronary intervention","Coronary artery disease","Remote ischemic conditioning","acute coronary syndrome","Acute kidney injury","Major adverse kidney events","Ischemic preconditioning","2025-12-09",{"date":126,"type":127},"2025-12-15","ACTUAL",{"date":129,"type":127},"2021-11-01",{"date":131,"type":100},"2029-03-31",{"name":5,"class":6},3]