Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorRoswell Park Cancer Institute

About this trial

This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer. Patients with lung cancer who choose to undergo surgical resection often have complications after surgery such as pneumonia, unplanned intubations, difficulty breathing and reduced physical functioning, and increased medical costs and a reduced quality of life. Improving pre-surgical pulmonary health through respiratory muscle training may improve respiratory muscle strength, response to surgery, and quality of life after surgery in patients with lung cancer.

Eligibility criteria

Qualifiers

Documented stage I-IIIb lung cancer or is undergoing surgery for diagnosis

Participant is able to speak, read, and comprehend English

Participant must be undergoing or is anticipated to either video-assisted thoracic surgery (VATS or robotic surgery) or laparoscopic surgery for curative intent lung resection

Patients with or without neoadjuvant chemoradiotherapy (CRT) prior to surgery will be included

Disqualifiers

Documented ischemic heart disease; congestive heart failure or; significant cardiac arrhythmias that would exclude them from having surgery

Overall medical frailty (clinician discretion) or ECOG > 2

Pregnant or nursing female participants

Unwilling or unable to follow protocol requirements

Trial design

Treatments tested in this trial

  • Best Practice
  • Laparoscopic Surgery
  • Quality-of-Life Assessment
  • Questionnaire Administration
  • Respiratory Muscle Training Device
  • Video-Assisted Thoracic Surgery

Treatment groups

220 Participants
are divided into 2 treatment groups

Locations

1
Roswell Park Cancer Institute14263, BuffaloNew York, United States

Sponsors and collaborators

Roswell Park Cancer Institute

Lead sponsor

National Cancer Institute (NCI)

Collaborator