[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628042":3},{"organization":4,"outcomesModule":7,"designInfo":17,"detailedDescription":16,"studyPopulation":16,"armGroups":25,"interventions":36,"overallOfficials":41,"centralContacts":46,"locations":51,"responsibleParty":68,"collaborators":16,"id":70,"slug":16,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":16,"eligibilityCriteria":74,"healthyVolunteers":71,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":16,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":16,"overallStatus":54,"whyStopped":16,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Liaquat National Hospital & Medical College","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":16},[9,13],{"measure":10,"description":11,"timeFrame":12},"Change in axial length in mm","Axial length is measured at the time of recruiting the participants and after the end of study","6 months",{"measure":14,"description":15,"timeFrame":12},"Change in refraction in Diopters","Refraction is measured at the start of study then after 6 months of study",null,{"allocation":18,"interventionModel":19,"interventionModelDescription":16,"primaryPurpose":20,"observationalModel":16,"timePerspective":16,"maskingInfo":21},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":22,"maskingDescription":16,"whoMasked":23},"SINGLE",[24],"PARTICIPANT",[26,32],{"label":27,"type":28,"description":29,"interventionNames":30},"Group A","ACTIVE_COMPARATOR","Atropine 0.01% eye drops",[31],"Drug: Atropine 0.01% eye drops",{"label":33,"type":34,"description":35,"interventionNames":16},"Group B","NO_INTERVENTION","No eye drops",[37],{"type":38,"name":29,"description":39,"armGroupLabels":40,"otherNames":16},"DRUG","Eye drops atropine 0.01% given once nightly to group A for 6 months",[27],[42],{"name":43,"affiliation":44,"role":45},"Hina Nadeem, MBBS","LNHMC","PRINCIPAL_INVESTIGATOR",[47],{"name":43,"role":48,"phone":49,"phoneExt":16,"email":50},"CONTACT","03252120568","hinanadeem1508@gmail.com",[52],{"facility":53,"status":54,"city":55,"state":56,"zip":16,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"LiaquatNHMC","RECRUITING","Karachi","Sindh","Pakistan","PK",{"type":60,"coordinates":61},"Point",[62,63],67.0104,24.8608,{"lat":63,"lon":62},[66],{"name":67,"role":48,"phone":49,"phoneExt":16,"email":50},"Hina Nadeem",{"type":45,"investigatorFullName":67,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":16,"oldOrganization":16},"Dr. Hina Nadeem, principal Investigator","100628042",false,"NCT07456488","The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control Group","Inclusion Criteria:\n\n* Children aged 4-16 years\n* Both genders\n* Myopia of baseline SER of -1.00D or more\n* Astigmatism less than or equal to -2.50D\n* No medical history predisposing severe myopia (e.g., Marfan syndrome, Stickler syndrome, and retinopathy of prematurity), abnormal ocular refractive anatomy (e.g., keratoconus, lenticonus, and spherophakia)\n* No history of other vision-threatening ocular diseases or previous intraocular surgery.\n* No current or previous use of atropine or pirenzipine, contact lenses or other forms of treatment that may affect myopia progression.\n\nExclusion Criteria:\n\n* Astigmatism ≥ 2.5 D\n* Anisometropia\\>1 D\n* Best corrected visual acuity \\\u003C 0.5 (6\u002F12)\n* Prior intraocular surgery\n* Allergy to atropine eye drops\n* Systemic diseases associated with myopia such as Marfan syndrome, Stickler syndrome\n* History of cardiac or significant respiratory diseases\n* Lack of consent for participating in the study","ALL","4 Years","16 Years",{"count":79,"type":80},60,"ESTIMATED","INTERVENTIONAL",[83],"PHASE2","In this study, atropine 0.01% eye drops will be given to myopic children once at night daily for 6 months as compared to a control group to see the effect on axial length and refraction",[86],"Focus on Axial Length","2026-03-03",{"date":89,"type":90},"2026-03-06","ACTUAL",{"date":92,"type":90},"2025-07-13",{"date":94,"type":80},"2026-04-30",{"name":5,"class":6},1]