[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568412":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":21,"interventions":33,"overallOfficials":13,"centralContacts":42,"locations":13,"responsibleParty":48,"collaborators":13,"id":52,"slug":13,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":13,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":72,"whyStopped":13,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":13},{"fullName":5,"class":6},"The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"overall efficacy rate","Symptoms were assessed both one week prior to and one week following treatment. The defecation time (scored as follows: 0 for ≤5 minutes; 1 for \\>5 to ≤15 minutes; 2 for \\>15 to ≤25 minutes; and 3 for \\>25 minutes) and the inter defecation interval (scored as the number of hours divided by 24) were recorded. The efficacy index was calculated using the formula: \\[(pretreatment score - posttreatment score)\u002F pretreatment score\\] × 100%.","From enrollment to the end of treatment at one week",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"RANDOMIZED","PARALLEL","slow transmission constipation","TREATMENT",{"masking":20,"maskingDescription":13,"whoMasked":13},"NONE",[22,28],{"label":23,"type":24,"description":25,"interventionNames":26},"study group","EXPERIMENTAL","The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride",[27],"Other: Auricular Acupoint Stimulation +prucapride",{"label":29,"type":6,"description":30,"interventionNames":31},"control group","also consisting of 30 patients, was administered prucapride as a monotherapy.",[32],"Drug: prucapride",[34,37],{"type":6,"name":35,"description":25,"armGroupLabels":36,"otherNames":13},"Auricular Acupoint Stimulation +prucapride",[23],{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":13},"DRUG","prucapride","was administered prucapride as a monotherapy",[29],[43],{"name":44,"role":45,"phone":46,"phoneExt":13,"email":47},"Heng Deng, Dr.","CONTACT","+8613335510159","tangkun23@outlook.com",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Heng Deng","The Second hospital affiliated Anhui University of Chinese Medicine","100568412",false,"NCT06680882","The Effect of Non-invasive Auricular Acupoint Stimulation on Slow Transmission Constipation","The Second Hospital Affiliated Anhui University of Chinese Medicine","AAS","Inclusion Criteria: ① Conformity to the diagnostic benchmarks for STC as delineated in the Rome IV criteria; ② Absence of ingestion of any medication influencing gastrointestinal motility within the preceding three months; ③ Provision of informed consent after a comprehensive understanding of the study's objectives; ④ An age range of 40 to 75 years.\n\n\\-\n\nExclusion Criteria: ① Withdrawal from the therapeutic regimen; ② Auricle or ear canal pathologies; ③ Organic defecation disorder; ④ Pregnant or lactating.\n\n\\-","ALL","40 Years","75 Years",{"count":63,"type":64},60,"ESTIMATED","INTERVENTIONAL",[67],"PHASE2","Objective To examine the therapeutic effect and safety of non-invasive auricular acupoint stimulation application on patients with slow transmission constipation.\n\nMethods In a randomized clinical trial, 60 patients diagnosed with slow transit constipation (STC), ranging in age from 40 to 75 years, were allocated into two distinct cohorts: a study group and a control group. The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride, while the control group, also consisting of 30 patients, was administered prucapride as a monotherapy. To assess the efficacy of the interventions, various parameters were monitored, including serum levels of Neuropeptide Y (NPY), nitric oxide (NO), fecal water content, and gastrointestinal (GI) transit. The comparative therapeutic outcomes were determined by calculating symptom scores.",[70],"Slow Transmission Constipation",[17],"NOT_YET_RECRUITING","2024-11-06",{"date":75,"type":76},"2024-11-08","ACTUAL",{"date":78,"type":64},"2024-11-07",{"date":80,"type":64},"2025-11-01",{"name":5,"class":6}]