[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634518":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":38,"centralContacts":47,"locations":53,"responsibleParty":73,"collaborators":75,"id":80,"slug":30,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":30,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":30,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":102,"whyStopped":30,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: intracochlear triamcinolone acetonide injection","EXPERIMENTAL","intracochlear injection of triamcinolone acetonide through the round window membrane",[13],"Drug: Experimental: Group A: intracochlear triamcinolone acetonide injection",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B: intracochlear dexamethasone injection","intracochlear injection of dexamethasone through the round window membrane",[18],"Drug: intracochlear injection of dexamethasone",{"label":20,"type":21,"description":22,"interventionNames":23},"Group C: intratympanic dexamethasone injection","ACTIVE_COMPARATOR","intratympanic dexamethasone injection through tympanic membrane",[24],"Device: intratympanic dexamethasone injection",[26,31,34],{"type":27,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"DRUG","Experimental: Group A: intracochlear triamcinolone acetonide injection",[9],null,{"type":27,"name":32,"description":16,"armGroupLabels":33,"otherNames":30},"intracochlear injection of dexamethasone",[15],{"type":35,"name":36,"description":22,"armGroupLabels":37,"otherNames":30},"DEVICE","intratympanic dexamethasone injection",[20],[39,43,45],{"name":40,"affiliation":41,"role":42},"Yilai Shu, MD, Ph.D","Eye & ENT Hospital, Fudan University, Shanghai, China","PRINCIPAL_INVESTIGATOR",{"name":44,"affiliation":41,"role":42},"Huawei Li, MD, Ph.D",{"name":46,"affiliation":41,"role":42},"Wuqing Wang, MD, Ph.D",[48],{"name":49,"role":50,"phone":51,"phoneExt":30,"email":52},"Wei Li, MD, Ph.D","CONTACT","0086-18301969566","619liwei@163.com",[54],{"facility":55,"status":30,"city":56,"state":57,"zip":58,"country":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Fenyang Road 83","Shanghai","Shanghai Municipality","200031","China",{"type":61,"coordinates":62},"Point",[63,64],121.45806,31.22222,{"lat":64,"lon":63},[67,69,70,71],{"name":68,"role":50,"phone":51,"phoneExt":30,"email":52},"Wei Li, MD, PhD",{"name":40,"role":42,"phone":30,"phoneExt":30,"email":30},{"name":44,"role":42,"phone":30,"phoneExt":30,"email":30},{"name":72,"role":42,"phone":30,"phoneExt":30,"email":30},"Wuqing Li, MD, Ph.D",{"type":74,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR",[76,78],{"name":77,"class":6},"Shanghai Zhongshan Hospital",{"name":79,"class":6},"Shenzhen Second People's Hospital","100634518",false,"NCT07540728","Trans-round Window Membrane Intracochlear Steroid","Efficacy and Safety of Trans-Round Window Membrane Intracochlear Steroid Delivery in Patients With Complete Sudden Sensorineural Hearing Loss","Inclusion Criteria:\n\n* Age between 12 and 75 years Unilateral idiopathic sudden sensorineural hearing loss diagnosed by Pure tone test, CT and MRI Symptoms of sudden deafness occur within ≥ 7 days and, after conventional treatment, the average thresholds at 500 Hz, 1000 Hz, 2000 Hz and 4000 Hz are ≥ 80 dBHL\n\nExclusion Criteria:\n\n* Bilateral sudden sensorineural hearing loss Hearing loss with known causes (e.g., Meniere's disease, retrocochlear pathology, history of otologic surgery, perilymphatic fistula, barotrauma) History in the past 6 months of ototoxic treatment such as chemotherapy, use of loop diuretics, high dose aspirin, etc.\n\nHistory of sudden sensorineural hearing loss within the past 2 years History of ischemic diseases (cerebral infarction, myocardial infarction, peripheral arterial obstructive disease) Neuropsychiatric disorders (epilepsy, Parkinson's disease, Alzheimer's disease, multiple sclerosis) Severe hepatic or renal insufficiency","ALL","12 Years","75 Years",{"count":90,"type":91},108,"ESTIMATED","INTERVENTIONAL",[94],"PHASE2","Safety and efficacy of intracochlear injection of glucocorticoid through the round window membrane in patients with profound or complete sudden sensorineural hearing loss",[97],"Sudden Hearing Loss",[99,100,101],"intracochlear injection","glucocorticoid","round window membrane","NOT_YET_RECRUITING","2026-04-13",{"date":105,"type":106},"2026-04-20","ACTUAL",{"date":105,"type":91},{"date":109,"type":91},"2028-05-01",{"name":5,"class":6},1]