[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588034":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":11,"studyPopulation":11,"armGroups":19,"interventions":28,"overallOfficials":11,"centralContacts":34,"locations":40,"responsibleParty":55,"collaborators":11,"id":57,"slug":11,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":11,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":43,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Ain Shams University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"To determine the effectiveness of probiotics to decrease the weight gained as a result of antipsychotic medications.",null,"12 weeks",{"allocation":14,"interventionModel":15,"interventionModelDescription":11,"primaryPurpose":16,"observationalModel":11,"timePerspective":11,"maskingInfo":17},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":18,"maskingDescription":11,"whoMasked":11},"NONE",[20,25],{"label":21,"type":22,"description":11,"interventionNames":23},"Probiotic supplementation (Lacteol fort 10 billion) which contains culture medium and lactobacillus","EXPERIMENTAL",[24],"Drug: lactobacillus LS",{"label":26,"type":27,"description":11,"interventionNames":11},"Participants will be advised to be adherent to their standard treatment and followed up regularly.","NO_INTERVENTION",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"DRUG","lactobacillus LS","Probiotic supplementation (Lacteol fort 10 billion) which contains culture medium and lactobacillus LS as active ingredients",[21],[35],{"name":36,"role":37,"phone":38,"phoneExt":11,"email":39},"Rehab Abdelmaksoud","CONTACT","02 01158336110","rehab.abdelmaksoud@med.asu.edu.eg",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":11},"AinShams university hospitals","RECRUITING","Cairo","Abbassia","00202","Egypt","EG",{"type":50,"coordinates":51},"Point",[52,53],31.24967,30.06263,{"lat":53,"lon":52},{"type":56,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100588034",false,"NCT06936137",": EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)","Inclusion Criteria:\n\n* Adult schizophrenia patients (18-45 years) on second generation antipsychotics Stable patients with a total positive and negative syndrome scale (PANSS) score of ≤60.\n\nWith more than 10% weight gain after taking atypical antipsychotics for at least 3 months with treatment duration not more than two years.\n\nExclusion Criteria:\n\n1. Taking probiotics, fiber supplements, antibiotics and laxatives in the last 6 weeks.\n2. Comorbid gastrointestinal diseases, including active peptic ulcer, uncontrolled and recurrent diarrhea, gastrointestinal bleeding, and digestive system neoplastic diseases.\n\n   \\-","ALL","18 Years","45 Years",{"count":66,"type":67},180,"ESTIMATED","INTERVENTIONAL",[70],"PHASE3","the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment.\n\nPrimary objective:\n\n1.To determine the effectiveness of probiotics to decrease the weight gained as a result of antipsychotic medications.\n\nSecondary objective:\n\n1\\. To determine the effect of probiotic supplementation on the psychological state of patients.",[73],"Antipsychotic Induced Weight Gain","2025-04-18",{"date":76,"type":77},"2025-04-20","ACTUAL",{"date":76,"type":67},{"date":80,"type":67},"2026-12-20",{"name":5,"class":6},1]