[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527161":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":43,"centralContacts":47,"locations":56,"responsibleParty":138,"collaborators":31,"id":140,"slug":31,"hasResults":141,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":31,"eligibilityCriteria":145,"healthyVolunteers":141,"sex":146,"minAge":147,"maxAge":148,"enrollmentInfo":149,"targetDuration":31,"studyType":152,"phases":153,"briefSummary":155,"conditions":156,"keywords":163,"overallStatus":59,"whyStopped":31,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":179},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants with Breast Cancer","EXPERIMENTAL","Participants will have a diagnosis of breast cancer and may undergo axillary lymph node dissection.",[13,14,15,16,17],"Procedure: Immediate Lymphatic Reconstruction","Diagnostic Test: Volumetric arm measurements","Other: Lymphatic massage","Other: Range of motion exercises","Other: Compression garment use",[19,26,32,36,39],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Immediate Lymphatic Reconstruction","Immediate Lymphatic Reconstruction will happen at the time of Axillary Lymph Node Dissection",[9],[25],"ILR",{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIAGNOSTIC_TEST","Volumetric arm measurements","Volumetric arm measurements will occur at each in-person postoperative visit time points.",[9],null,{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Lymphatic massage","Participants will begin self-directed lymphatic massage 24 to 48 h after surgery and will continue to do lymphatic massage 3 times a week for 3 months after surgery or until 3 months after any adjuvant treatments (chemotherapy, radiation, etc.) are completed",[9],{"type":6,"name":37,"description":34,"armGroupLabels":38,"otherNames":31},"Range of motion exercises",[9],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":31},"Compression garment use","Participants will use compression garments 24 to 48 h after surgery and will continue daily use for at least 8 h a day for 3 months or until 3 months after any adjuvant treatments are completed",[9],[44],{"name":45,"affiliation":5,"role":46},"Michelle Coriddi, MD","PRINCIPAL_INVESTIGATOR",[48,52],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":51},"CONTACT","646-608-8042","coriddim@mskcc.org",{"name":53,"role":49,"phone":54,"phoneExt":31,"email":55},"Babak Mahrara, MD","646-608-8085","mehrarab@MSKCC.ORG",[57,72,83,94,106,117,127],{"facility":58,"status":59,"city":60,"state":61,"zip":62,"country":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)","RECRUITING","Basking Ridge","New Jersey","07920","United States",{"type":65,"coordinates":66},"Point",[67,68],-74.54932,40.70621,{"lat":68,"lon":67},[71],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":73,"status":59,"city":74,"state":61,"zip":75,"country":63,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Memorial Sloan Kettering Monmouth (Limited Protocol Activities)","Middletown","07748",{"type":65,"coordinates":77},[78,79],-74.11709,40.39428,{"lat":79,"lon":78},[82],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":84,"status":59,"city":85,"state":61,"zip":86,"country":63,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Memorial Sloan Kettering Bergen (Limited Protocol Activities)","Montvale","07645",{"type":65,"coordinates":88},[89,90],-74.02292,41.04676,{"lat":90,"lon":89},[93],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":95,"status":59,"city":96,"state":97,"zip":98,"country":63,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Memorial Sloan Kettering Commack (Limited Protocol Activities)","Commack","New York","11725",{"type":65,"coordinates":100},[101,102],-73.29289,40.84288,{"lat":102,"lon":101},[105],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":107,"status":59,"city":108,"state":97,"zip":109,"country":63,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"Memorial Sloan Kettering Westchester (Limited Protocol Activities)","Harrison","10604",{"type":65,"coordinates":111},[112,113],-73.71263,40.96899,{"lat":113,"lon":112},[116],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":118,"status":59,"city":97,"state":97,"zip":119,"country":63,"cosmosGeoPoint":120,"geoPoint":124,"contacts":125},"Memorial Sloan Kettering Cancer Center (All Protocol Activities)","10065",{"type":65,"coordinates":121},[122,123],-74.00597,40.71427,{"lat":123,"lon":122},[126],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":128,"status":59,"city":129,"state":97,"zip":130,"country":63,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"Memorial Sloan Kettering Nassau (Limited Protocol Activities)","Uniondale","11553",{"type":65,"coordinates":132},[133,134],-73.59291,40.70038,{"lat":134,"lon":133},[137],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"type":139,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100527161",false,"NCT06144164","A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer","A Prospective Cohort Study of Patients Undergoing ALND for Treatment of Breast Cancer: The Efficacy of a Comprehensive Prevention Program in Decreasing the Incidence of Lymphedema and Improving Quality of Life","Inclusion Criteria:\n\n* Female sex\n* Diagnosis of breast cancer\n* Ages 18 to 75 years\n* Consented for unilateral ALND or for unilateral SLNB with possible ALND\n\nExclusion Criteria:\n\n* Male sex\n* Does not speak English\n* Does not fit into study garment\n* Axillary recurrence\n* History of ALND\n* Requirement of bilateral ALND for the treatment of breast cancer\n* Treatment with SLNB only\n* Known anaphylactic allergy to ICG dye used in ILR\n* Impaired decision-making capacity","FEMALE","18 Years","75 Years",{"count":150,"type":151},285,"ESTIMATED","INTERVENTIONAL",[154],"PHASE3","The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.",[157,158,159,160,161,162],"Lymphedema","Lymphedema Arm","Lymphedema of Upper Arm","Breast Cancer","Breast Carcinoma","Female Breast Cancer",[164,165,157,158,159,166,167,168,5,169],"immediate lymphatic reconstruction","axillary lymph node dissection","Breast cancer","breast carcinoma","female breast cancer","23-303","2025-11-06",{"date":172,"type":173},"2025-11-10","ACTUAL",{"date":175,"type":173},"2023-11-16",{"date":177,"type":151},"2030-03-16",{"name":5,"class":6},7]