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PPDS","Greater London","WC1N 3JH","United Kingdom","UK",{"type":73,"coordinates":698},[699,700],-0.12574,51.50853,{"lat":700,"lon":699},{"facility":703,"status":66,"city":704,"state":705,"zip":706,"country":695,"countryCode":696,"cosmosGeoPoint":707,"geoPoint":711,"contacts":11},"Royal Hospital for Children and Young People - PIN","Edinburgh","Midlothian","EH16 4TJ",{"type":73,"coordinates":708},[709,710],-3.19648,55.95206,{"lat":710,"lon":709},{"facility":713,"status":66,"city":714,"state":233,"zip":715,"country":695,"countryCode":696,"cosmosGeoPoint":716,"geoPoint":720,"contacts":11},"James Paget University Hospitals NHS Foundation Trust","Great Yarmouth","NR31 6LA",{"type":73,"coordinates":717},[718,719],1.73052,52.60831,{"lat":719,"lon":718},{"facility":722,"status":66,"city":723,"state":11,"zip":724,"country":695,"countryCode":696,"cosmosGeoPoint":725,"geoPoint":729,"contacts":11},"Queen Elizabeth University Hospital - PPDS","Glasgow","G514TF",{"type":73,"coordinates":726},[727,728],-4.25763,55.86515,{"lat":728,"lon":727},{"type":731,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100451874",false,"NCT05164172","A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine","Long-term, Open-label (Dose-blinded), Extension Study of Eptinezumab in Children and Adolescents With Chronic or Episodic Migraine","REJOIN","Inclusion Criteria:\n\n\\- The participant must have completed Week12 (completion) visit of either Study19356A (CM) or Study19357A (EM) immediately prior to enrolment into this OLE study.\n\nExclusion Criteria:\n\n* The participant has an adverse event or other safety concerns that are deemed related to double-blind treatment received in the lead-in study and is considered a potential safety risk by the investigator.\n* During lead-in Study19356A or Study19357A:\n* participant experienced ananaphylactic reaction or another severe and\u002For serious hypersensitivity reaction to the investigational medicinal product (IMP) infusion, as assessed by the investigator\n* the participant had a serum alanine aminotransferase (ALT) or aspartate aminotransferase(AST) value \\>5 times the upper limit of the reference range that was confirmed by testing \\\u003C2 weeks later.\n* the participant had a serum ALT or AST value \\>3times the upper limit of the reference range and a serum total bilirubin value \\>2times the upper limit of the reference range.","ALL","6 Years","17 Years",{"count":743,"type":744},600,"ESTIMATED","INTERVENTIONAL",[747],"PHASE3","The main goal of the study is to assess the long-term safety of eptinezumab on children and adolescents ages 6 to 17 with chronic or episodic migraine.",[750],"Migraine","2026-06-11",{"date":753,"type":754},"2026-06-12","ACTUAL",{"date":756,"type":754},"2021-12-01",{"date":758,"type":744},"2028-04-30",{"name":5,"class":6},70]