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Pathologically diagnosed with recurrent nasopharyngeal carcinoma;\n2. Stage rT1 or rT2(superficial parapharyngeal space, distance to internal carotid artery \\>5mm)or rT3 (confined to the bottom wall of the sphenoid sinus),according to AJCC 8th edition;\n3. Cervical lymph node metastasis can be controlled locally\n4. Age 18 to 75 years;\n5. Without distant metastasis;\n6. Informed consent forms signed;\n7. ≥6months from the accomplishment of radiation to recurrence\n8. previously radiotherapy for only 1 course;\n9. ECOG score 0-2 and can tolerate chemotherapy and immunotherapy\n10. Sufficient organ function;\n11. Undergone endoscopic surgery with negative pathological margin;\n\nExclusion Criteria:\n\n1. Participation in other interventional clinical trials;\n2. Uncontrolled illnesses which will interfere with the ability to undergo therapy;\n3. Suffering from another or multiple malignancy within 5 years (excluding fully treated basal cell or skin squamous cell carcinoma, cervical carcinoma in situ);\n4. Any contradiction to immune and chemotherapy;\n5. With serious autoimmune disease;\n6. Currently usage of immunosuppressive agents or systemic glucocorticoid therapy (dosage\\>10mg\u002Fday prednisone or other glucocorticoids), and continuing to use them within 2 weeks before the first administration of trial drugs;\n7. Severe allergic reactions to other monoclonal antibodies;\n8. History of radioactive particle planting;\n9. Vaccination with live vaccine within 4 weeks prior to initial administration or possibly during the study period;\n10. Female patients who are at pregnancy or lactation;\n11. Other situations that the researchers believe are not suitable for enrollment","ALL","18 Years","75 Years",{"count":168,"type":169},176,"ESTIMATED","INTERVENTIONAL",[172],"PHASE3",[174],"Recurrent Nasopharyngeal Carcinoma","2025-07-01",{"date":177,"type":178},"2025-07-04","ACTUAL",{"date":180,"type":178},"2024-06-25",{"date":182,"type":169},"2028-06-30",{"name":5,"class":6},7]