[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643877":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":132,"collaborators":25,"id":134,"slug":25,"hasResults":135,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":135,"sex":141,"minAge":142,"maxAge":25,"enrollmentInfo":143,"targetDuration":25,"studyType":146,"phases":147,"briefSummary":149,"conditions":150,"keywords":25,"overallStatus":153,"whyStopped":25,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":163},{"fullName":5,"class":6},"Novo Nordisk A\u002FS","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Zenagamtide","EXPERIMENTAL","Participants will be randomized to receive 1 out of 3 different dose levels subcutaneously once weekly.",[13],"Drug: Zenagamtide",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Participants will receive placebo matched to Zenagamtide subcutaneously once weekly.",[19],"Drug: Placebo ( matched to Zenagamtide)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Zenagamtide will be administered subcutaneously using PDS290 pre-filled pen-injectors to one of the body parts: thigh, abdomen or upper arm.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Placebo ( matched to Zenagamtide)","Placebo matched to Zenagamtide will be administered subcutaneously using PDS290 pre-filled pen-injectors to one of the body parts: thigh, abdomen or upper arm.",[15],[31],{"name":32,"affiliation":5,"role":33},"Clinical Transparency (dept. 2834)","STUDY_DIRECTOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Novo Nordisk","CONTACT","(+1) 866-867-7178","clinicaltrials@novonordisk.com",[41,53,62,67,76,86,96,105,111,120,126],{"facility":42,"status":25,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":25},"Nirmal Hospital Pvt. 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Once-weekly in Asian Participants With Overweight or Obesity (AMAZE 13)","AMAZE 13","Inclusion Criteria:\n\n* Male or female (sex assigned at birth, inclusive of all gender identities).\n* Age 18 years or above at the time of signing the informed consent\n\nExclusion Criteria:\n\n* Glycated haemoglobin (HbA1c) ≥ 6.5% (48 mmol\u002Fmol) as measured by the central laboratory at screening.\n* History of type 1 or type 2 diabetes mellitus.\n* Treatment with glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1\u002Fgastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues before screening.","ALL","18 Years",{"count":144,"type":145},400,"ESTIMATED","INTERVENTIONAL",[148],"PHASE3","The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get zenagamtide (the treatment being tested) or placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.",[151,152],"Obesity","Overweight","NOT_YET_RECRUITING","2026-06-19",{"date":156,"type":157},"2026-06-25","ACTUAL",{"date":159,"type":145},"2027-01-07",{"date":161,"type":145},"2029-01-11",{"name":5,"class":6},11]