[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507690":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":160,"collaborators":162,"id":170,"slug":26,"hasResults":171,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":171,"sex":177,"minAge":178,"maxAge":26,"enrollmentInfo":179,"targetDuration":26,"studyType":182,"phases":183,"briefSummary":185,"conditions":186,"keywords":189,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":200},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group","EXPERIMENTAL","Study participants in the active study arm will receive a daily oral dose of 0.5 mg Colchicine for 3 months without a loading dose. The dose is recommended to be taken in the morning. There is no deviation from the usual treatment intake.",[13],"Drug: Colchicine",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","PLACEBO_COMPARATOR","Study participants in the placebo group will receive a matched placebo.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Colchicine","Colchicine 0.5 mg (oral) once daily for 90 days. The chemical name for colchicine is (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9 oxobenzol\\[a\\]heptalen-7-yl) acetamide.\n\nColchicine consists of pale yellow scales or powder. It is soluble in water, freely soluble in alcohol, and slightly soluble in ether.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Matched placebo. Both the active drug and placebo will look similarly. The route and mode of administration is also similar to the active group.",[15],[32],{"name":33,"affiliation":5,"role":34},"Philipp Krisai, PD Dr. med.","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+41 61 265 25 25","Philipp.krisai@usb.ch",[41,54,73,87,102,117,132,147],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":26,"geoPoint":26,"contacts":48},"Cantonal Hospital Baselland (KSBL)","RECRUITING","Bruderholz","Basel-Landschaft","4101","Switzerland",[49,53],{"name":50,"role":37,"phone":51,"phoneExt":26,"email":52},"Christian Maurer, Dr. med.","+41 61 436 21 90","christian.maurer@ksbl.ch,",{"name":50,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":55,"status":43,"city":56,"state":26,"zip":57,"country":47,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"University Hospital Basel","Basel","4031",{"type":59,"coordinates":60},"Point",[61,62],7.57327,47.55839,{"lat":62,"lon":61},[65,69,70,71],{"name":66,"role":37,"phone":67,"phoneExt":26,"email":68},"Christian Sticherling, Prof.","+41 61 265 55 26","christian.sticherling@usb.ch",{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},{"name":66,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":33,"role":72,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"facility":74,"status":43,"city":75,"state":26,"zip":76,"country":47,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"University Hospital Bern","Bern","3010",{"type":59,"coordinates":78},[79,80],7.44744,46.94809,{"lat":80,"lon":79},[83,86],{"name":84,"role":37,"phone":26,"phoneExt":26,"email":85},"Tobias Reichlin, Prof.","tobias.reichlin@insel.ch",{"name":84,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":88,"status":43,"city":89,"state":26,"zip":90,"country":47,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Lausanne University Hospital","Lausanne","1011",{"type":59,"coordinates":92},[93,94],6.63282,46.516,{"lat":94,"lon":93},[97,101],{"name":98,"role":37,"phone":99,"phoneExt":26,"email":100},"Etienne Pruvot, Prof. Dr.","+41 21 314 11 11","etienne.pruvot@chuv.ch",{"name":98,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":103,"status":43,"city":104,"state":26,"zip":105,"country":47,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Lucerne Cantonal Hospital","Lucerne","6000",{"type":59,"coordinates":107},[108,109],8.30635,47.05048,{"lat":109,"lon":108},[112,116],{"name":113,"role":37,"phone":114,"phoneExt":26,"email":115},"Ann-Kathrin Gamer, MD","+41 41 205 18 77","annkathrin.gamer@luks.ch",{"name":113,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":118,"status":43,"city":119,"state":26,"zip":120,"country":47,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"Cantonal Hospital Olten","Olten","4600",{"type":59,"coordinates":122},[123,124],7.90329,47.34999,{"lat":124,"lon":123},[127,131],{"name":128,"role":37,"phone":129,"phoneExt":26,"email":130},"Frank-Peter Stephan, MD","+41 32 627 35 52","frank-peter.stephan@spital.so.ch",{"name":128,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":133,"status":43,"city":134,"state":26,"zip":135,"country":47,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Herzpraxis am Rhein","Rheinfelden","4310",{"type":59,"coordinates":137},[138,139],7.79403,47.55437,{"lat":139,"lon":138},[142,146],{"name":143,"role":37,"phone":144,"phoneExt":26,"email":145},"Flavio Scarcia, MD","+41 61 836 99 88","herzpraxisamrhein@hin.ch",{"name":143,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":148,"status":43,"city":149,"state":26,"zip":150,"country":47,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Solothurner Spitäler AG","Solothurn","4500",{"type":59,"coordinates":152},[153,154],7.53714,47.20791,{"lat":154,"lon":153},[157,158],{"name":128,"role":37,"phone":129,"phoneExt":26,"email":130},{"name":159,"role":34,"phone":26,"phoneExt":26,"email":26},"Frank-Peter Stephan",{"type":161,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[163,165,168],{"name":164,"class":6},"Swiss Heart Foundation",{"name":166,"class":167},"Fondation Machaon, Switzerland, Genf","UNKNOWN",{"name":169,"class":167},"Foundation for Cardiovascular Research Basel","100507690",false,"NCT05890664","Colchicine After Electrocardioversion for Atrial Fibrillation","Colchicine After Electrocardioversion for Atrial Fibrillation - The COLECTRO-AF Trial","COLECTRO-AF","Inclusion Criteria:\n\n* Age \\>18 years\n* ECG-documented AF prior to ECV\n* Successful ECV with conversion of AF to sinus rhythm with persistent sinus rhythm ≥30 minutes after ECV\n* Ability to give written informed consent\n\nExclusion Criteria:\n\n* AF persistence after cardioversion or early AF recurrence within 30 minutes after ECV\n* Any other rhythm than AF before cardioversion\n* Pulmonary vein isolation within 3 months prior to ECV or pulmonary vein isolation planned within 3 months after ECV\n* Known intolerance or hypersensitivity to Colchicine\n* Any other absolute indication for Colchicine intake\n* Intake of a strong inhibitor of CYP3A4 or P-Glycoprotein (clarithromycin, erythromycin, telithromycin, cyclosporine, ketoconazole or itraconazole)\n* Serious gastrointestinal disease (severe gastritis or diarrhea)\n* Clinically overt hepatic disease\n* Severe renal disease (eGFR\\< 30ml\u002Fmin\u002F1.73m2)\n* Clinically significant blood dyscrasia (e.g., myelodysplasia)\n* Significant immunosuppression (e.g. due to transplantation or rheumatic disease)\n* Pregnant or breastfeeding women, or women of child-bearing potential who do not use a highly effective form of birth control\n* Life expectancy \\<1 year","ALL","18 Years",{"count":180,"type":181},416,"ESTIMATED","INTERVENTIONAL",[184],"PHASE3","The purpose of this study is to investigate whether a 3 month treatment course of low-dose Colchicine decreases the recurrence of Atrial fibrillation (AF) after electrocardioversion (ECV) in patients with AF.",[187,188],"Atrial Fibrillation","Cardiac Arrhythmia",[190,23],"Electrocardioversion","2025-05-21",{"date":193,"type":194},"2025-05-28","ACTUAL",{"date":196,"type":194},"2024-04-14",{"date":198,"type":181},"2027-03",{"name":5,"class":6},8]