[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619357":3},{"organization":4,"outcomesModule":7,"designInfo":43,"detailedDescription":42,"studyPopulation":42,"armGroups":52,"interventions":64,"overallOfficials":42,"centralContacts":72,"locations":78,"responsibleParty":97,"collaborators":100,"id":103,"slug":42,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":42,"eligibilityCriteria":108,"healthyVolunteers":104,"sex":109,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":42,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":121,"overallStatus":125,"whyStopped":42,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"Al-Azhar University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":42},[9],{"measure":10,"description":11,"timeFrame":12},"Cumulative opioid consumption in the first 24 hours postoperatively","Measures the total amount of opioid analgesics (expressed as morphine milligram equivalents, MME) consumed during the first postoperative 24 hours. It reflects overall analgesic efficacy of the two block techniques.","24 hours after surgery.",[14,18,21,25,28,31,35,39],{"measure":15,"description":16,"timeFrame":17},"Pain intensity (VAS pain scores at rest )","Assesses the level of postoperative pain at rest using the Visual Analogue Scale (VAS), where 0 = no pain and 10 = worst imaginable pain.","24 hours postoperatively.",{"measure":19,"description":20,"timeFrame":17},"Pain intensity (VAS pain scores at movement)","Assesses the level of postoperative pain during movement using the Visual Analogue Scale (VAS), where 0 = no pain and 10 = worst imaginable pain.",{"measure":22,"description":23,"timeFrame":24},"Time to first analgesic request","Determines the duration of effective analgesia provided by each block, defined as the interval from completion of the block to the first patient request for additional analgesia.","24 hours.",{"measure":26,"description":27,"timeFrame":24},"Proportion of patients requiring rescue opioid analgesia","Percentage of patients who required additional opioid analgesics beyond the planned postoperative regimen, indicating inadequate analgesia from the primary block.",{"measure":29,"description":30,"timeFrame":24},"Incidence of postoperative block-related complications","Evaluates safety of the blocks by recording complications such as hematoma, local anesthetic toxicity, or impaired mobility.",{"measure":32,"description":33,"timeFrame":34},"Patient satisfaction score","Patient satisfaction with postoperative pain control will be evaluated using a 5-point Likert scale, allowing a simple yet reliable measure of the patient's overall analgesic experience. Each participant will rate their satisfaction as follows: 1 for \"very dissatisfied,\" indicating poor pain relief and marked discomfort; 2 for \"dissatisfied,\" reflecting inadequate but tolerable pain control; 3 for \"neutral,\" representing acceptable analgesia without a clear sense of satisfaction; 4 for \"satisfied,\" denoting good pain relief and minimal discomfort; and 5 for \"very satisfied,\" corresponding to excellent pain control and full contentment with the postoperative analgesia regimen.","Assessed at 24 hours postoperatively.",{"measure":36,"description":37,"timeFrame":38},"Post-anesthesia care unit (PACU) stay duration","Measures the time spent in the PACU","24 hours",{"measure":40,"description":41,"timeFrame":38},"Total hospital stay duration","Measures total length of hospital stay.",null,{"allocation":44,"interventionModel":45,"interventionModelDescription":42,"primaryPurpose":46,"observationalModel":42,"timePerspective":42,"maskingInfo":47},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":48,"maskingDescription":42,"whoMasked":49},"DOUBLE",[50,51],"PARTICIPANT","OUTCOMES_ASSESSOR",[53,59],{"label":54,"type":55,"description":56,"interventionNames":57},"Group 1 (Quadratus lumborum block)","ACTIVE_COMPARATOR","Ultrasound-guided lateral quadratus lumborum block. Local anesthetic: 30 ml of (Ropivacaine 0.2%) is injected at the appropriate fascial level.",[58],"Procedure: Ultrasound-guided lateral quadratus lumborum block",{"label":60,"type":55,"description":61,"interventionNames":62},"Group 2 ( Ilio-inguinal and ilio-hypogastric block)","Ultrasound-guided ilio-inguinal and ilio-hypogastric block. Local anesthesia: 20 ml of 0.2% ropivacaine for ilio-inguinal and ilio-hypogastric block + 10 ml of 0.2% ropivacaine for genitofemoral anaesthesia, total injection volume = 30 ml.",[63],"Procedure: Combined ilio-inguinal\u002Filio-hypogastric\u002Fgenitofemoral (II-IH-GFN) block",[65,69],{"type":66,"name":67,"description":56,"armGroupLabels":68,"otherNames":42},"PROCEDURE","Ultrasound-guided lateral quadratus lumborum block",[54],{"type":66,"name":70,"description":61,"armGroupLabels":71,"otherNames":42},"Combined ilio-inguinal\u002Filio-hypogastric\u002Fgenitofemoral (II-IH-GFN) block",[60],[73],{"name":74,"role":75,"phone":76,"phoneExt":42,"email":77},"Neveen A. Kohaf, Ph.D","CONTACT","01060383012","nevenabdo@azhar.edu.eg",[79],{"facility":80,"status":42,"city":81,"state":82,"zip":83,"country":82,"countryCode":84,"cosmosGeoPoint":85,"geoPoint":90,"contacts":91},"Al Azhar University","Cairo","Egypt","11865","EG",{"type":86,"coordinates":87},"Point",[88,89],31.24967,30.06263,{"lat":89,"lon":88},[92,94],{"name":93,"role":75,"phone":76,"phoneExt":42,"email":77},"Neveen Kohaf, Ph.D",{"name":95,"role":96,"phone":42,"phoneExt":42,"email":42},"Hany Baumy, M.D","PRINCIPAL_INVESTIGATOR",{"type":96,"investigatorFullName":98,"investigatorTitle":99,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Neveen Abd El Maksoad Kohaf","Lecturer of Clinical Pharmacy",[101],{"name":102,"class":6},"Benha University","100619357",false,"NCT07343570","Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia Repair.","Comparing Ultrasound-guided Lateral Quadratus Lumborum Block Versus Combined Ilio-inguinal\u002FIlio-hypogastric \u002FGenitofemoral Block for Postoperative Analgesia After Open Inguinal Hernia Repair: A Double-blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18-75 years.\n* ASA physical status I-III.\n* Scheduled for elective unilateral open inguinal hernia repair under standardized spinal anesthesia.\n* Able to understand and use the Visual Analogue Scale (VAS).\n* Provided written informed consent.\n\nExclusion Criteria:\n\n* Allergy to local anesthetics.\n* Coagulopathy or current use of anticoagulants contraindicating peripheral nerve blocks.\n* Infection at the injection site.\n* Chronic opioid use (daily opioids \\>2 weeks) or chronic pain syndromes.\n* Body mass index (BMI) \\>40 kg\u002Fm².\n* Conversion to other surgery or bilateral repair.\n* Pregnant patients.\n* Refusal to sign informed consent.","ALL","18 Years","75 Years",{"count":113,"type":114},66,"ESTIMATED","INTERVENTIONAL",[117],"PHASE3","This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal\u002Filio-hypogastric\u002Fgenitofemoral (II-IH-GFN) block-for postoperative analgesia after elective unilateral open inguinal hernia repair under spinal anesthesia in adults.",[120],"Postoperative Analgesia of Inguinal Hernia Repair in Adults",[122,123,124],"Quadratus lumborum [QL] block","Ilioinguinal-iliohypogastric (IIIH) nerve block","Genitofemoral block","NOT_YET_RECRUITING","2026-01-08",{"date":128,"type":129},"2026-01-15","ACTUAL",{"date":131,"type":114},"2026-01-28",{"date":133,"type":114},"2026-12-30",{"name":5,"class":6},1]