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Atchison, MD","6053366294","jweisbrod@opltd.com",{"facility":735,"status":33,"city":736,"state":737,"zip":738,"country":37,"cosmosGeoPoint":739,"geoPoint":743,"contacts":744},"Southeastern Retina Associates","Hixson","Tennessee","37343",{"type":39,"coordinates":740},[741,742],-85.23273,35.14063,{"lat":742,"lon":741},[745],{"name":746,"role":47,"phone":747,"phoneExt":23,"email":748},"Francis C. DeCroos, MD","423-756-1002","kschratter@seretina.com",{"facility":750,"status":33,"city":751,"state":737,"zip":752,"country":37,"cosmosGeoPoint":753,"geoPoint":757,"contacts":758},"Southeastern Retina Associates, P.C.","Knoxville","37922",{"type":39,"coordinates":754},[755,756],-83.92074,35.96064,{"lat":756,"lon":755},[759],{"name":760,"role":47,"phone":761,"phoneExt":23,"email":762},"R. K. Shuler, Jr., MD","865-588-0811","jwalsh@seretina.com",{"facility":764,"status":33,"city":765,"state":766,"zip":767,"country":37,"cosmosGeoPoint":768,"geoPoint":772,"contacts":773},"Austin Research Center for Retina","Austin","Texas","78705",{"type":39,"coordinates":769},[770,771],-97.74306,30.26715,{"lat":771,"lon":770},[774],{"name":775,"role":47,"phone":776,"phoneExt":23,"email":777},"Chirag Jhaveri, MD","737-704-0130","beatris.ramirez@nvisioncenters.com",{"facility":779,"status":33,"city":780,"state":766,"zip":781,"country":37,"cosmosGeoPoint":782,"geoPoint":786,"contacts":787},"Retina Consultants of Texas, PA","Bellaire","77401",{"type":39,"coordinates":783},[784,785],-95.45883,29.70579,{"lat":785,"lon":784},[788],{"name":789,"role":47,"phone":790,"phoneExt":23,"email":791},"Charles C. Wykoff, MD, PhD","713-524-3434","ilsa.ortega@retinaconsultantstexas.com",{"facility":793,"status":33,"city":794,"state":766,"zip":795,"country":37,"cosmosGeoPoint":796,"geoPoint":800,"contacts":801},"UT Southwestern Medical Center","Dallas","75390",{"type":39,"coordinates":797},[798,799],-96.80667,32.78306,{"lat":799,"lon":798},[802],{"name":803,"role":47,"phone":804,"phoneExt":23,"email":805},"Judy E. Kim, MD","214-645-2012","Juan.Mo@UTSouthwestern.edu",{"facility":807,"status":33,"city":808,"state":766,"zip":809,"country":37,"cosmosGeoPoint":810,"geoPoint":814,"contacts":815},"Southwest Retina Consultants","El Paso","79902",{"type":39,"coordinates":811},[812,813],-106.48693,31.75872,{"lat":813,"lon":812},[816],{"name":817,"role":47,"phone":818,"phoneExt":23,"email":819},"Richard Y Hwang, MD","9155323912","ceciliasambrano3@gmail.com",{"facility":821,"status":33,"city":822,"state":766,"zip":823,"country":37,"cosmosGeoPoint":824,"geoPoint":828,"contacts":829},"Baylor College of Medicine, Baylor Eye Physicians and Surgeons","Houston","77030-4101",{"type":39,"coordinates":825},[826,827],-95.36327,29.76328,{"lat":827,"lon":826},[830],{"name":831,"role":47,"phone":832,"phoneExt":23,"email":833},"Christina Y. Weng, MD, MBA","713-798-3493","Becky.Chatham@bcm.edu",{"facility":835,"status":33,"city":836,"state":766,"zip":837,"country":37,"cosmosGeoPoint":838,"geoPoint":842,"contacts":843},"Texas Retina Associates","Lubbock","79424",{"type":39,"coordinates":839},[840,841],-101.85517,33.57786,{"lat":841,"lon":840},[844],{"name":845,"role":47,"phone":846,"phoneExt":23,"email":847},"Michel Shami, MD","806-792-0066","ysaldivar@texasretina.com",{"facility":849,"status":33,"city":850,"state":766,"zip":851,"country":37,"cosmosGeoPoint":852,"geoPoint":856,"contacts":857},"Retina Associates of South Texas","San Antonio","78240",{"type":39,"coordinates":853},[854,855],-98.49363,29.42412,{"lat":855,"lon":854},[858],{"name":859,"role":47,"phone":860,"phoneExt":23,"email":861},"Juan E. Rubio, MD","2106157600","jcervantes@retinastx.com",{"facility":863,"status":33,"city":850,"state":766,"zip":851,"country":37,"cosmosGeoPoint":864,"geoPoint":866,"contacts":867},"Retinal Consultants of Texas",{"type":39,"coordinates":865},[854,855],{"lat":855,"lon":854},[868],{"name":869,"role":47,"phone":870,"phoneExt":23,"email":871},"Moises A. Chica, MD","210-615-1311","olivia.gonzales@retinaconsultantstexas.com",{"facility":873,"status":33,"city":874,"state":875,"zip":876,"country":37,"cosmosGeoPoint":877,"geoPoint":881,"contacts":882},"The Board of Regents of the University of Wisconsin System","Madison","Wisconsin","53705",{"type":39,"coordinates":878},[879,880],-89.40123,43.07305,{"lat":880,"lon":879},[883],{"name":884,"role":47,"phone":885,"phoneExt":23,"email":886},"Kathleen Schildroth","608-263-7290","kadietzman@wisc.edu",{"facility":888,"status":33,"city":889,"state":875,"zip":890,"country":37,"cosmosGeoPoint":891,"geoPoint":895,"contacts":896},"Eye Clinic of Wisconsin","Wausau","54403",{"type":39,"coordinates":892},[893,894],-89.63012,44.95914,{"lat":894,"lon":893},[897],{"name":898,"role":47,"phone":899,"phoneExt":23,"email":900},"Deepak Sambhara, MD","8002618500","ottoser@eyeclinicwi.com",{"facility":902,"status":33,"city":903,"state":904,"zip":905,"country":906,"cosmosGeoPoint":23,"geoPoint":23,"contacts":907},"Chow Berger Koushan Medicine Professional Corporation o\u002Fa Toronto Retina Institute","North YORK","Ontario","M3C0G9","Canada",[908],{"name":909,"role":47,"phone":910,"phoneExt":23,"email":911},"Keyvan Koushan","416-449-3937","Mayuri.triresearch@gmail.com",{"facility":913,"status":33,"city":914,"state":904,"zip":915,"country":906,"cosmosGeoPoint":916,"geoPoint":920,"contacts":921},"University Health Network","Toronto","M5T 2S8",{"type":39,"coordinates":917},[918,919],-79.39864,43.70643,{"lat":919,"lon":918},[922],{"name":923,"role":47,"phone":924,"phoneExt":23,"email":925},"Michael H. Brent, MD, FRCSC","416-603-5444","Judy.Hung@uhn.ca",{"type":927,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[929,932,934],{"name":930,"class":931},"National Institutes of Health (NIH)","NIH",{"name":933,"class":931},"National Eye Institute (NEI)",{"name":935,"class":6},"Juvenile Diabetes Research Foundation","100508715",false,"NCT05904028","Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD","AO","Key Inclusion Criteria:\n\n* Age ≥ 50 years\n* Have the capacity to consent on his\u002Fher own behalf\n* Able to successfully and independently complete at least one self-scanning session on the Home OCT device located at the enrolling clinical site\n* Willing to perform once daily Home OCT monitoring tests for 2 years without significant interruption (such as travel of more than 14 days)\n* Best corrected E-ETDRS visual acuity ≥24 ETDRS letters (approximately 20\u002F320 or better (Snellen))\n* Previously untreated, active MNV lesion (i.e., any intraretinal or subretinal fluid within the center 3 mm diameter circle on OCT) secondary to age-related macular degeneration\n* ≥ 1 intermediate drusen (≥ 63 microns) in either eye OR late AMD (MNV or macular atrophy) in the contralateral eye\n\nKey Exclusion Criteria for Study Eye:\n\n* Previous treatment for MNV (intravitreal injection of any anti-VEGF or anti-VEGF\u002Fanti-Ang2 agent, or any other AMD therapy)\n* Prior treatment with intravitreal injection of any anti-VEGF or anti-VEGF\u002Fanti-Ang2 agent or with macular laser for any indication\n* Treatment with intravitreal corticosteroids within the last 6 months\n* A condition that, in the opinion of the investigator, would preclude participation in the study or ability to complete daily Home OCT scans for 2 years (e.g., unstable medical status that may preclude successful completion of follow-up, dementia, Alzheimer's disease, uncontrollable tremors)\n* MNV due to other causes, such as ocular histoplasmosis, central serous choroidopathy, or pathologic myopia","ALL","50 Years",{"count":945,"type":946},600,"ESTIMATED","INTERVENTIONAL",[949],"PHASE3","Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.",[952],"Neovascular Age-related Macular Degeneration",[954],"optical coherence tomography","2026-05-15",{"date":957,"type":958},"2026-05-18","ACTUAL",{"date":960,"type":958},"2023-11-09",{"date":962,"type":946},"2027-07-30",{"name":5,"class":6},65]