[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586043":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":11,"locations":27,"responsibleParty":47,"collaborators":49,"id":52,"slug":11,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":11,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":11,"overallStatus":30,"whyStopped":11,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Florida Atlantic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lidocaine","ACTIVE_COMPARATOR",null,[13],"Drug: Lidocaine",{"label":15,"type":16,"description":11,"interventionNames":17},"Diphenhydramine","EXPERIMENTAL",[18],"Drug: Diphenhydramine",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","Lidocaine local infiltration",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Diphenhydramine local infiltration",[15],[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Bethesda Hospital East","RECRUITING","Boynton Beach","Florida","33435","United States",{"type":36,"coordinates":37},"Point",[38,39],-80.06643,26.52535,{"lat":39,"lon":38},[42],{"name":43,"role":44,"phone":45,"phoneExt":11,"email":46},"Scott M Alter, MD","CONTACT","561-733-5933","alters@health.fau.edu",{"type":48,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[50],{"name":51,"class":6},"Baptist Health South Florida","100586043",false,"NCT06910241","Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs","Inclusion Criteria:\n\n* Lacerations requiring one layer of sutures\n* Lacerations appropriate for repair by emergency physicians\n\nExclusion Criteria:\n\n* Active bleeding from laceration\n* Complex lacerations requiring multiple layers\n* Lacerations to be repaired by a specialist service\n* Patients with allergies to either diphenhydramine or lidocaine\n* Laceration repairs would benefit from the use of epinephrine as an additive to the local anesthetic",true,"ALL","18 Years",{"count":61,"type":62},100,"ESTIMATED","INTERVENTIONAL",[65],"PHASE3","Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for simple laceration repair. Patients who present to the emergency department with a simple laceration will be enrolled in the study. Patients will be evaluated for the pain of the injection as well as the pain of the laceration repair procedure post injection.",[68],"Laceration of Skin","2026-01-06",{"date":71,"type":72},"2026-01-07","ACTUAL",{"date":74,"type":72},"2025-09-03",{"date":76,"type":62},"2028-06-30",{"name":5,"class":6},1]