[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100211102":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":19,"studyPopulation":11,"armGroups":20,"interventions":42,"overallOfficials":64,"centralContacts":69,"locations":79,"responsibleParty":96,"collaborators":11,"id":99,"slug":11,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":100,"sex":105,"minAge":106,"maxAge":11,"enrollmentInfo":107,"targetDuration":11,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":82,"whyStopped":11,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"University of Washington","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Size of chalazion",null,"4 weeks",{"allocation":14,"interventionModel":15,"interventionModelDescription":11,"primaryPurpose":16,"observationalModel":11,"timePerspective":11,"maskingInfo":17},"RANDOMIZED","SINGLE_GROUP","TREATMENT",{"masking":18,"maskingDescription":11,"whoMasked":11},"NONE","This is a prospective randomized interventional study comparing four current standard-of-care treatments for chalazia: incision and curettage, local injection of triamcinolone, local injection of 5-FU, and local injection of combination triamcinolone\u002F5-FU.",[21,27,32,37],{"label":22,"type":23,"description":24,"interventionNames":25},"Incision and Curettage","ACTIVE_COMPARATOR","A vertical incision over the area of chalazion will be done. Inflammatory material will be removed and the chalazion capsule will be excised.",[26],"Procedure: Incision and Curettage",{"label":28,"type":23,"description":29,"interventionNames":30},"Injection of Triamcinolone Acetonide","0.1 ml of triamcinolone is injected directly in the chalazion.",[31,26],"Drug: Triamcinolone Acetonide",{"label":33,"type":23,"description":34,"interventionNames":35},"Injection of 5-fluorouracil","0.1 ml of 5-fluorouracil is injected directly in the lesion transconjunctivally.",[36,26],"Drug: 5-fluorouracil Injection",{"label":38,"type":23,"description":39,"interventionNames":40},"Injection of triamcinolone\u002F5FU mixture","0.1 ml of a 4:1 mixture of 4 parts 5-FU and 1 part triamcinolone is injected in the lesion.",[26,41],"Drug: Triamcinolone Acetonide\u002F5-fluorouracil mixture",[43,50,56,60],{"type":44,"name":45,"description":46,"armGroupLabels":47,"otherNames":48},"DRUG","5-fluorouracil Injection","If the chalazion is present at follow-up visit, another injection of 5-FU will be given.",[33],[49],"5-FU",{"type":44,"name":51,"description":52,"armGroupLabels":53,"otherNames":54},"Triamcinolone Acetonide","If chalazion present at follow-up, another Triamcinolone injection will be done.",[28],[55],"triamcinolone",{"type":57,"name":22,"description":58,"armGroupLabels":59,"otherNames":11},"PROCEDURE","If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone\u002F5-FU mixture.",[22,33,28,38],{"type":44,"name":61,"description":62,"armGroupLabels":63,"otherNames":11},"Triamcinolone Acetonide\u002F5-fluorouracil mixture","If chalazion persists at follow-up visit, another injection of triamcinolone\u002F5-FU mixture will be done.",[38],[65],{"name":66,"affiliation":67,"role":68},"Matthew M Zhang, MD","University of Washington Eye Institute","PRINCIPAL_INVESTIGATOR",[70,75],{"name":71,"role":72,"phone":73,"phoneExt":11,"email":74},"Simona Vuletic","CONTACT","206-520-9728","simona@uw.edu",{"name":76,"role":72,"phone":77,"phoneExt":11,"email":78},"Ian Luttrell","206-520-8305","lutri@uw.edu",[80],{"facility":81,"status":82,"city":83,"state":84,"zip":85,"country":86,"countryCode":87,"cosmosGeoPoint":88,"geoPoint":93,"contacts":94},"University of Washington Eye Institute at Harborview","RECRUITING","Seattle","Washington","98104","United States","US",{"type":89,"coordinates":90},"Point",[91,92],-122.33207,47.60621,{"lat":92,"lon":91},[95],{"name":71,"role":72,"phone":73,"phoneExt":11,"email":74},{"type":68,"investigatorFullName":97,"investigatorTitle":98,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Matthew Zhang","Assistant Professor of Ophthalmology","100211102",false,"NCT02025023","Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study","CTS","Inclusion Criteria:\n\n* Single or multiple chalazia in a single eyelid\n\nExclusion Criteria:\n\n* Chalazia present for less than one month and no previous injection or incision and curettage","ALL","18 Years",{"count":108,"type":109},120,"ESTIMATED","INTERVENTIONAL",[112],"PHASE3","Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.",[115],"Chalazion",[117,118,119,120,121],"Size","Pain","Resolution","Complications","Swelling","2020-02-04",{"date":124,"type":125},"2020-02-06","ACTUAL",{"date":127,"type":11},"2013-12",{"date":129,"type":109},"2026-07",{"name":5,"class":6},1]