[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578350":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":24,"locations":30,"responsibleParty":85,"collaborators":12,"id":89,"slug":12,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":12,"eligibilityCriteria":94,"healthyVolunteers":90,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":12,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":111,"whyStopped":12,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"University of Calgary","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","Infants will not receive any probiotics.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Multi-strain probiotics","EXPERIMENTAL","Infants will be started on probiotics (Bifidobacterium and Lacticaseibacillus) within 24 hours of commencing enteral feeds.",[18],"Biological: Multi-strain probiotics",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BIOLOGICAL","Infants will be started on probiotics (Bifidobacterium and Lacticaseibacillus) with enetral feed.",[14],[25],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},"Belal N Alshaikh, MD, MSc","CONTACT","+1 403 956 1588","balshaik@ucalgary.ca",[31,45,58,72],{"facility":32,"status":12,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Foothills Medical Center","Calgary","Alberta","T2Z 2G9","Canada",{"type":38,"coordinates":39},"Point",[40,41],-114.08529,51.05011,{"lat":41,"lon":40},[44],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},{"facility":46,"status":12,"city":47,"state":34,"zip":12,"country":36,"cosmosGeoPoint":48,"geoPoint":52,"contacts":53},"Royal Alexandra Hospital","Edmonton",{"type":38,"coordinates":49},[50,51],-113.46871,53.55014,{"lat":51,"lon":50},[54],{"name":55,"role":27,"phone":56,"phoneExt":12,"email":57},"Kumar Kumaran, MD","780-735-5179","kumar.kumaran@ahs.ca",{"facility":59,"status":12,"city":60,"state":61,"zip":12,"country":36,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Children's and Women's health of Britch Columbia","Vancouver","British Columbia",{"type":38,"coordinates":63},[64,65],-123.11934,49.24966,{"lat":65,"lon":64},[68],{"name":69,"role":27,"phone":70,"phoneExt":12,"email":71},"Horacio Osiovich, MD","604- 875-2345","hosiovich@cw.bc.ca",{"facility":73,"status":12,"city":74,"state":12,"zip":12,"country":36,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"IWK","Halifax",{"type":38,"coordinates":76},[77,78],-63.57688,44.64269,{"lat":78,"lon":77},[81],{"name":82,"role":27,"phone":83,"phoneExt":12,"email":84},"Balpreet Singh, MD","902-470-7055","balpreet.singh@iwk.nshealth.ca",{"type":86,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Belal Alshaikh","Principle investigator","100578350",false,"NCT06810154","Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants","Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants: a Stepped-Wedge Cluster Randomized Trial","Inclusion Criteria:\n\n* Infants born between \\\u003C32 0\u002F7 weeks gestation.\n\nExclusion Criteria:\n\n* Major congenital or chromosomal abnormalities\n* Conditions affecting gastrointestinal systems that prohibit infants from starting on feed in the first 72 hours after birth.","ALL","0 Hours","72 Hours",{"count":99,"type":100},2170,"ESTIMATED","INTERVENTIONAL",[103],"PHASE3","The goal of this clinical trial is to evaluate whether multi-strain probiotics of lactobacillus and bifidobacterium can prevent necrotizing enterocolitis (NEC) in preterm infants born at less than 32 weeks of gestation. The main questions it aims to answer are:\n\n* Does the use of a multi-strain probiotic combination reduce the incidence of NEC in preterm infants?\n* Are there any adverse effects associated with the administration of this probiotic combination?",[106],"Necrotizing Enterocolitis (NEC)",[108,109,110],"Probiotics","Necrotizing enteroclitis","preterm infants","NOT_YET_RECRUITING","2025-01-30",{"date":114,"type":115},"2025-02-05","ACTUAL",{"date":117,"type":100},"2025-06-01",{"date":119,"type":100},"2028-05-30",{"name":5,"class":6},4]