About this trial

The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain perfusion. We use contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography to evaluate the state of brain perfusion. We will study neonates recruited from the Neonatal Units of Turku University Hospital.

Eligibility criteria

Qualifiers

Babies less than 7 months treated at the neonatal units of Turku University hospital

Disqualifiers

Pre-known genetic disease

Difficult congenital malformations that need surgical treatment

Central nervous system tumors

Weight less than 2,5 kg during examination

Trial design

Treatments tested in this trial

  • Brain contrast enhanced ultrasound, brain ultrasound elastography
  • Sulfur Hexafluoride

Treatment groups

100 Participants
are divided into 4 treatment groups

Locations

1
Turku University Hospital20520, TurkuSouthwestern Finland, Finland

Sponsors and collaborators

Turku University Hospital

Lead sponsor