[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484674":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":627,"collaborators":629,"id":633,"slug":26,"hasResults":634,"nctId":635,"briefTitle":636,"officialTitle":636,"acronym":637,"eligibilityCriteria":638,"healthyVolunteers":634,"sex":639,"minAge":640,"maxAge":26,"enrollmentInfo":641,"targetDuration":26,"studyType":644,"phases":645,"briefSummary":647,"conditions":648,"keywords":650,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":652,"lastUpdatePostDateStruct":653,"startDateStruct":656,"completionDateStruct":658,"leadSponsor":660,"locationsCount":661},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Catheter-Directed Therapy (CDT) plus Anticoagulation","EXPERIMENTAL","Participants will receive CDT consisting of mechanical thrombectomy (MT) or intrathrombus catheter-directed thrombolysis (CDL) using FDA-cleared devices for pulmonary embolism (PE). The exact technique and devices used will be at the discretion of the endovascular physician, within parameters defined by the PE-TRACT Manual of Operations (MOP) and accepted standard care. Before and after CDT, patients will receive standard PE therapy as in the no-CDT Arm.",[13,14],"Drug: Anticoagulant Therapy","Device: Catheter-Directed Therapy",{"label":16,"type":17,"description":18,"interventionNames":19},"No Catheter-Directed Therapy (No-CDT)","ACTIVE_COMPARATOR","Standard anticoagulant therapy (FDA-approved regimen) for the treatment of PE.",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Anticoagulant Therapy","All subjects will receive anticoagulation for a minimum of 3 months.",[9,16],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Catheter-Directed Therapy","The endovascular physician can choose to use either mechanical thrombectomy (MT) using a device cleared by the FDA to treat PE or catheter-directed thrombolysis (CDL) using an infusion catheter cleared by the FDA to administer thrombolytic drugs for the treatment of PE",[9],[33],{"name":34,"affiliation":5,"role":35},"Sunil Rao, MD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Sunil Rao","CONTACT","212-263-0456","Sunil.rao@nyulangone.org",{"name":43,"role":39,"phone":44,"phoneExt":26,"email":45},"Lei Lei","212-263-4189","Lei.lei@nyulangone.org",[47,65,80,94,108,122,138,153,169,183,199,214,229,243,257,272,287,303,315,330,344,359,373,388,402,413,424,439,453,468,479,493,507,522,537,552,567,581,596,612],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"The University of Alabama At Birmingham","RECRUITING","Birmingham","Alabama","35233","United States",{"type":55,"coordinates":56},"Point",[57,58],-86.80249,33.52066,{"lat":58,"lon":57},[61],{"name":62,"role":39,"phone":63,"phoneExt":26,"email":64},"Samuel McElwee, MD","205-975-7123","skmcelwee@uabmc.edu",{"facility":66,"status":49,"city":67,"state":68,"zip":69,"country":53,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Stanford Medicine","Palo Alto","California","94304",{"type":55,"coordinates":71},[72,73],-122.14302,37.44188,{"lat":73,"lon":72},[76],{"name":77,"role":39,"phone":78,"phoneExt":26,"email":79},"Andrew Kesselman, MD","650-723-6855","ajk266@stanford.edu",{"facility":81,"status":49,"city":82,"state":68,"zip":83,"country":53,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"UC Davis Health","Sacramento","95817",{"type":55,"coordinates":85},[86,87],-121.4944,38.58157,{"lat":87,"lon":86},[90],{"name":91,"role":39,"phone":92,"phoneExt":26,"email":93},"Roger Goldman","916-734-8462","regoldman@ucdavis.edu",{"facility":95,"status":49,"city":96,"state":68,"zip":97,"country":53,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Scripps Memorial Hospital, La Jolla","San Diego","92121",{"type":55,"coordinates":99},[100,101],-117.16472,32.71571,{"lat":101,"lon":100},[104],{"name":105,"role":39,"phone":106,"phoneExt":26,"email":107},"Daniel S. Jones, MD","215-908-5726","Jones.Daniel@scrippshealth.org",{"facility":109,"status":49,"city":110,"state":68,"zip":111,"country":53,"cosmosGeoPoint":112,"geoPoint":116,"contacts":117},"The Lundquist Institute","Torrance","90502",{"type":55,"coordinates":113},[114,115],-118.34063,33.83585,{"lat":115,"lon":114},[118],{"name":119,"role":39,"phone":120,"phoneExt":26,"email":121},"Janine Vintch, MD","310-222-8200","jvintch@dhs.lacounty.gov",{"facility":123,"status":49,"city":124,"state":125,"zip":126,"country":53,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Christiana Care","Newark","Delaware","19718",{"type":55,"coordinates":128},[129,130],-75.74966,39.68372,{"lat":130,"lon":129},[133,137],{"name":134,"role":39,"phone":135,"phoneExt":26,"email":136},"George Kimbiris, MD","302-733-5625","gkimbiris@christianacare.org",{"name":134,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":139,"status":49,"city":140,"state":141,"zip":142,"country":53,"cosmosGeoPoint":143,"geoPoint":147,"contacts":148},"MedStar Health Research Institute","Washington D.C.","District of Columbia","20010",{"type":55,"coordinates":144},[145,146],-77.03637,38.89511,{"lat":146,"lon":145},[149],{"name":150,"role":39,"phone":151,"phoneExt":26,"email":152},"Saher Sabri, MD","202-877-3657","saher.s.sabri@medstar.net",{"facility":154,"status":49,"city":155,"state":156,"zip":157,"country":53,"cosmosGeoPoint":158,"geoPoint":162,"contacts":163},"Baptist Health Miami Cardiac & Vascular Institute","Miami","Florida","33176",{"type":55,"coordinates":159},[160,161],-80.19366,25.77427,{"lat":161,"lon":160},[164,168],{"name":165,"role":39,"phone":166,"phoneExt":26,"email":167},"Ripal Gandhi, MD","786-596-5990","gandhi@baptisthealth.net",{"name":165,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":170,"status":49,"city":171,"state":156,"zip":172,"country":53,"cosmosGeoPoint":173,"geoPoint":177,"contacts":178},"University of South Florida\u002F Tampa General Hospital","Tampa","33606",{"type":55,"coordinates":174},[175,176],-82.45843,27.94752,{"lat":176,"lon":175},[179],{"name":180,"role":39,"phone":181,"phoneExt":26,"email":182},"Glenn Hoots, MD","813-844-4570","hoots@usf.edu",{"facility":184,"status":49,"city":185,"state":186,"zip":187,"country":53,"cosmosGeoPoint":188,"geoPoint":192,"contacts":193},"Emory University School of Medicine","Atlanta","Georgia","30308",{"type":55,"coordinates":189},[190,191],-84.38798,33.749,{"lat":191,"lon":190},[194,198],{"name":195,"role":39,"phone":196,"phoneExt":26,"email":197},"Wissam Jabar, MD","404-686-7568","wissam.jaber@emory.edu",{"name":195,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":200,"status":49,"city":201,"state":202,"zip":203,"country":53,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"University of Chicago Medical Center","Chicago","Illinois","60637",{"type":55,"coordinates":205},[206,207],-87.65005,41.85003,{"lat":207,"lon":206},[210],{"name":211,"role":39,"phone":212,"phoneExt":26,"email":213},"Jonathan D. Paul, MD","773-834-1497","jpaul@medicine.bsd.uchicago.edu",{"facility":215,"status":49,"city":216,"state":202,"zip":217,"country":53,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Advocate Good Samaritan Hospital","Downers Grove","60515",{"type":55,"coordinates":219},[220,221],-88.01117,41.80892,{"lat":221,"lon":220},[224,228],{"name":225,"role":39,"phone":226,"phoneExt":26,"email":227},"Mahesh Raju, MD","630-719-4799","Mahesh.raju@aah.org",{"name":225,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":230,"status":49,"city":231,"state":202,"zip":232,"country":53,"cosmosGeoPoint":233,"geoPoint":237,"contacts":238},"Loyola University Chicago","Maywood","60153",{"type":55,"coordinates":234},[235,236],-87.84312,41.8792,{"lat":236,"lon":235},[239],{"name":240,"role":39,"phone":241,"phoneExt":26,"email":242},"Amir Darki, MD","708-216-4466","adarki@lumc.edu",{"facility":244,"status":49,"city":245,"state":202,"zip":246,"country":53,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"Southern Illinois University School of Medicine","Springfield","62781",{"type":55,"coordinates":248},[249,250],-89.64371,39.80172,{"lat":250,"lon":249},[253],{"name":254,"role":39,"phone":255,"phoneExt":26,"email":256},"Abdul Moiz Hafiz","217-545-8000","ahafiz96@siumed.edu",{"facility":258,"status":49,"city":259,"state":260,"zip":261,"country":53,"cosmosGeoPoint":262,"geoPoint":266,"contacts":267},"University of Iowa","Iowa City","Iowa","52242",{"type":55,"coordinates":263},[264,265],-91.53017,41.66113,{"lat":265,"lon":264},[268],{"name":269,"role":39,"phone":270,"phoneExt":26,"email":271},"Kevin Doerschug","319-356-1445","kevin-doerschug@uiowa.edu",{"facility":273,"status":49,"city":274,"state":275,"zip":276,"country":53,"cosmosGeoPoint":277,"geoPoint":281,"contacts":282},"MaineHealth","Portland","Maine","04102",{"type":55,"coordinates":278},[279,280],-70.2589,43.65737,{"lat":280,"lon":279},[283],{"name":284,"role":39,"phone":285,"phoneExt":26,"email":286},"Paul Kim, MD","207-956-6650","kimp9@spectrummg.com",{"facility":288,"status":49,"city":289,"state":290,"zip":291,"country":53,"cosmosGeoPoint":292,"geoPoint":296,"contacts":297},"Boston Medical Center","Boston","Massachusetts","02118",{"type":55,"coordinates":293},[294,295],-71.05977,42.35843,{"lat":295,"lon":294},[298,302],{"name":299,"role":39,"phone":300,"phoneExt":26,"email":301},"Ashvin Pande, MD","617-638-8703","Ashvin.pande@bmc.org",{"name":299,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":304,"status":49,"city":289,"state":290,"zip":305,"country":53,"cosmosGeoPoint":306,"geoPoint":308,"contacts":309},"Beth Israel Deaconess Medical Center","02215",{"type":55,"coordinates":307},[294,295],{"lat":295,"lon":294},[310,314],{"name":311,"role":39,"phone":312,"phoneExt":26,"email":313},"Brett Carroll, MD","617-667-8800","bcarrol2@bidmc.harvard.edu",{"name":311,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":316,"status":49,"city":317,"state":318,"zip":319,"country":53,"cosmosGeoPoint":320,"geoPoint":324,"contacts":325},"University of Michigan","Ann Arbor","Michigan","48109",{"type":55,"coordinates":321},[322,323],-83.74088,42.27756,{"lat":323,"lon":322},[326],{"name":327,"role":39,"phone":328,"phoneExt":26,"email":329},"Minhajuddin Khaja, MD, MBA","734-936-4478","mkhaja@med.umich.edu",{"facility":331,"status":49,"city":332,"state":318,"zip":333,"country":53,"cosmosGeoPoint":334,"geoPoint":338,"contacts":339},"Trinity Health - Ann Arbor Hospital","Ypsilanti","48197",{"type":55,"coordinates":335},[336,337],-83.61299,42.24115,{"lat":337,"lon":336},[340],{"name":341,"role":39,"phone":342,"phoneExt":26,"email":343},"Hriday Shah, MD","734-712-8350","hriday.shah@aiarad.com",{"facility":345,"status":49,"city":346,"state":347,"zip":348,"country":53,"cosmosGeoPoint":349,"geoPoint":353,"contacts":354},"Washington University in St. Louis","St Louis","Missouri","63110",{"type":55,"coordinates":350},[351,352],-90.19789,38.62727,{"lat":352,"lon":351},[355],{"name":356,"role":39,"phone":357,"phoneExt":26,"email":358},"Pavan Kavali, MD","314-362-2900","pavan.kavali@wustl.edu",{"facility":360,"status":49,"city":124,"state":361,"zip":362,"country":53,"cosmosGeoPoint":363,"geoPoint":367,"contacts":368},"Rutgers New Jersey Medical School","New Jersey","07103",{"type":55,"coordinates":364},[365,366],-74.17237,40.73566,{"lat":366,"lon":365},[369],{"name":370,"role":39,"phone":371,"phoneExt":26,"email":372},"Abhishek Kumar, M.D.","973-972-5188","kumarab@njms.rutgers.edu",{"facility":374,"status":49,"city":375,"state":376,"zip":377,"country":53,"cosmosGeoPoint":378,"geoPoint":382,"contacts":383},"University of New Mexico Health Sciences Center","Albuquerque","New Mexico","87131",{"type":55,"coordinates":379},[380,381],-106.65114,35.08449,{"lat":381,"lon":380},[384],{"name":385,"role":39,"phone":386,"phoneExt":26,"email":387},"Carolina Ponce Orellana, MD","505-272-6020","CPonceOr@salud.unm.edu",{"facility":389,"status":49,"city":390,"state":390,"zip":391,"country":53,"cosmosGeoPoint":392,"geoPoint":396,"contacts":397},"NYU Langone Health - Tisch Hospital","New York","10016",{"type":55,"coordinates":393},[394,395],-74.00597,40.71427,{"lat":395,"lon":394},[398],{"name":399,"role":39,"phone":400,"phoneExt":26,"email":401},"Bedros Taslakian, MD, EBIR, FCIRSE","332-237-9866","bedros.taslakian@nyulangone.org",{"facility":403,"status":49,"city":390,"state":390,"zip":404,"country":53,"cosmosGeoPoint":405,"geoPoint":407,"contacts":408},"Icahn School of Medicine at Mount Sinai","10029",{"type":55,"coordinates":406},[394,395],{"lat":395,"lon":394},[409],{"name":410,"role":39,"phone":411,"phoneExt":26,"email":412},"Hooman Poor, MD","212-241-5656","hooman.poor@mountsinai.org",{"facility":414,"status":49,"city":390,"state":390,"zip":415,"country":53,"cosmosGeoPoint":416,"geoPoint":418,"contacts":419},"Weill Cornell Medicine","10065",{"type":55,"coordinates":417},[394,395],{"lat":395,"lon":394},[420],{"name":421,"role":39,"phone":422,"phoneExt":26,"email":423},"Christopher M. Harnain, MD, MBA, RPVI","212.746.4635","cmh9017@med.cornell.edu",{"facility":425,"status":49,"city":426,"state":427,"zip":428,"country":53,"cosmosGeoPoint":429,"geoPoint":433,"contacts":434},"Promedica","Toledo","Ohio","43606",{"type":55,"coordinates":430},[431,432],-83.55521,41.66394,{"lat":432,"lon":431},[435],{"name":436,"role":39,"phone":437,"phoneExt":26,"email":438},"Zakaria Assi, MD","419-291-4438","zassi@buckeye-express.com",{"facility":440,"status":49,"city":274,"state":441,"zip":442,"country":53,"cosmosGeoPoint":443,"geoPoint":447,"contacts":448},"Oregon Health & Science University","Oregon","97239",{"type":55,"coordinates":444},[445,446],-122.67621,45.52345,{"lat":446,"lon":445},[449],{"name":450,"role":39,"phone":451,"phoneExt":26,"email":452},"Khashayar Farsad, MD, PhD","503-494-7226","farsad@ohsu.edu",{"facility":454,"status":49,"city":455,"state":456,"zip":457,"country":53,"cosmosGeoPoint":458,"geoPoint":462,"contacts":463},"University of Pennsylvania","Philadelphia","Pennsylvania","19104",{"type":55,"coordinates":459},[460,461],-75.16362,39.95238,{"lat":461,"lon":460},[464],{"name":465,"role":39,"phone":466,"phoneExt":26,"email":467},"Steven Pugliese, MD","215-614-1527","Steven.Pugliese@pennmedicine.upenn.edu",{"facility":469,"status":49,"city":455,"state":456,"zip":470,"country":53,"cosmosGeoPoint":471,"geoPoint":473,"contacts":474},"Thomas Jefferson University","19107",{"type":55,"coordinates":472},[460,461],{"lat":461,"lon":460},[475],{"name":476,"role":39,"phone":477,"phoneExt":26,"email":478},"Carin Gonsalves, MD","215-955-6609","Carin.Gonsalves@jefferson.edu",{"facility":480,"status":49,"city":481,"state":456,"zip":482,"country":53,"cosmosGeoPoint":483,"geoPoint":487,"contacts":488},"University of Pittsburgh Medical Center","Pittsburgh","15232",{"type":55,"coordinates":484},[485,486],-79.99589,40.44062,{"lat":486,"lon":485},[489],{"name":490,"role":39,"phone":491,"phoneExt":26,"email":492},"Rabih A. Chaer, MD","412-802-3025","chaerra@upmc.edu",{"facility":494,"status":49,"city":495,"state":456,"zip":496,"country":53,"cosmosGeoPoint":497,"geoPoint":501,"contacts":502},"Main Line Healh","Wynnewood","19096",{"type":55,"coordinates":498},[499,500],-75.27074,40.00289,{"lat":500,"lon":499},[503],{"name":504,"role":39,"phone":505,"phoneExt":26,"email":506},"Lee Greenspon, MD","610-642-3796","GreensponL@MLHS.ORG",{"facility":508,"status":49,"city":509,"state":510,"zip":511,"country":53,"cosmosGeoPoint":512,"geoPoint":516,"contacts":517},"Lifespan","Providence","Rhode Island","02903",{"type":55,"coordinates":513},[514,515],-71.41283,41.82399,{"lat":515,"lon":514},[518],{"name":519,"role":39,"phone":520,"phoneExt":26,"email":521},"DaeHee Kim, MD","401-444-5184","daehee_kim@brown.edu",{"facility":523,"status":49,"city":524,"state":525,"zip":526,"country":53,"cosmosGeoPoint":527,"geoPoint":531,"contacts":532},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":55,"coordinates":528},[529,530],-79.93275,32.77632,{"lat":530,"lon":529},[533],{"name":534,"role":39,"phone":535,"phoneExt":26,"email":536},"Kevin W. Dickey","843-792-5069","dickeyke@musc.edu",{"facility":538,"status":49,"city":539,"state":540,"zip":541,"country":53,"cosmosGeoPoint":542,"geoPoint":546,"contacts":547},"The University of Texas Health Science Center at Houston","Houston","Texas","77030",{"type":55,"coordinates":543},[544,545],-95.36327,29.76328,{"lat":545,"lon":544},[548],{"name":549,"role":39,"phone":550,"phoneExt":26,"email":551},"Bela Patel, MD","713-500-6831","Bela.patel@uth.tmc.edu",{"facility":553,"status":49,"city":554,"state":555,"zip":556,"country":53,"cosmosGeoPoint":557,"geoPoint":561,"contacts":562},"Intermountain Health","Murray","Utah","84107",{"type":55,"coordinates":558},[559,560],-111.88799,40.66689,{"lat":560,"lon":559},[563],{"name":564,"role":39,"phone":565,"phoneExt":26,"email":566},"Mark Dodson, MD","801-507-4603","Mark.Dodson@imail.org",{"facility":568,"status":49,"city":569,"state":555,"zip":570,"country":53,"cosmosGeoPoint":571,"geoPoint":575,"contacts":576},"University of Utah Health","Salt Lake City","84108",{"type":55,"coordinates":572},[573,574],-111.89105,40.76078,{"lat":574,"lon":573},[577],{"name":578,"role":39,"phone":579,"phoneExt":26,"email":580},"Nathan Hatton, MD","801-581-5811","nathan.hatton@hsc.utah.edu",{"facility":582,"status":49,"city":583,"state":584,"zip":585,"country":53,"cosmosGeoPoint":586,"geoPoint":590,"contacts":591},"Sentara Health Research Center","Norfolk","Virginia","23507",{"type":55,"coordinates":587},[588,589],-76.28522,36.84681,{"lat":589,"lon":588},[592],{"name":593,"role":39,"phone":594,"phoneExt":26,"email":595},"David Dexter, MD","757-388-5480","djdexte1@sentara.com",{"facility":597,"status":49,"city":598,"state":584,"zip":599,"country":53,"cosmosGeoPoint":600,"geoPoint":604,"contacts":605},"Carilion Clinic","Roanoke","24014",{"type":55,"coordinates":601},[602,603],-79.94143,37.27097,{"lat":603,"lon":602},[606,610],{"name":607,"role":39,"phone":608,"phoneExt":26,"email":609},"Joseph A. Hughes, M.D","540-981-7083","jahughes1@carilionclinic.org",{"name":611,"role":35,"phone":26,"phoneExt":26,"email":26},"Joseph Hughes, MD",{"facility":613,"status":49,"city":614,"state":615,"zip":616,"country":53,"cosmosGeoPoint":617,"geoPoint":621,"contacts":622},"Medical College of Wisconsin","Milwaukee","Wisconsin","53226",{"type":55,"coordinates":618},[619,620],-87.90647,43.0389,{"lat":620,"lon":619},[623],{"name":624,"role":39,"phone":625,"phoneExt":26,"email":626},"Matthew J. Scheidt, MD","414-805-3125","mscheidt@mcw.edu",{"type":628,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[630],{"name":631,"class":632},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100484674",false,"NCT05591118","Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy","PE-TRACT","Inclusion Criteria:\n\n1. Symptomatic PE diagnosed by contrast-enhanced CT angiography with involvement of a main or lobar pulmonary artery branch; and\n2. Right ventricular (RV) dilation as defined by the presence of an RV\u002FLeft ventricular ratio \\> 1 on CT angiography\n\nExclusion Criteria:\n\n1. Age \\\u003C 18 years\n2. Systolic blood pressure \\\u003C 90 mmHg for \\>15 consecutive minutes or \\> 40 mmHg drop from baseline, or vasopressor requirement for blood pressure support (i.e., massive PE), occurring within 1 hour prior to eligibility assessment.\n3. Symptom duration \\> 14 days for the current PE episode\n4. Irreversible INR \\> 3\n5. Irreversible Thrombocytopenia (Platelets \\\u003C 50,000\u002Fmicroliter)\n6. Creatinine \\> 2.0 mg\u002Fdl\n7. Hemoglobin \\\u003C 7.0 g\u002Fdl\n8. Pregnancy (positive urine or blood pregnancy test (a pregnancy test must be obtained within 7 days prior to randomization in people of childbearing potential))\n9. Allergy or hypersensitivity to Recombinant Tissue Plasminogen Activator (rt-PA), or iodinated contrast, except for mild-moderate contrast allergies for which steroid pre-medication can be used\n10. Life expectancy \\\u003C 1 year\n11. Chronic inability to independently walk prior to the current PE episode (e.g. wheelchair dependent, walker or cane dependent, paraplegic, and\u002For bed-bound)\n12. Allergy to heparin or history of Heparin-Induced Thrombocytopenia (HIT)\n13. Unable or unwilling to provide informed consent\n14. Major contraindication or unsuitability for all CDT methods available at the Clinical Center","ALL","18 Years",{"count":642,"type":643},500,"ESTIMATED","INTERVENTIONAL",[646],"PHASE3","PE-TRACT is an open-label, assessor-blinded, randomized trial, aiming to compare catheter-directed therapy (CDT) and anticoagulation (CDT group) with anticoagulation alone (No-CDT) in 500 patients with submassive PE, proximal pulmonary artery thrombus and right ventricular dilation.",[649],"Pulmonary Embolism",[651],"Catheter-Directed Therapy (CDT)","2026-05-15",{"date":654,"type":655},"2026-05-18","ACTUAL",{"date":657,"type":655},"2023-07-17",{"date":659,"type":643},"2027-08-04",{"name":5,"class":6},40]