About this trial

The goal of this clinical trial is to investigate the efficacy of semaglutide on body weight, insulin dose requirements and improvements in glucose control and safety aspects in regards to risk of hypoglycemia and diabetic ketoacidosis for patients with established Type 1 Diabetes.

Eligibility criteria

Qualifiers

Type 1 Diabetes for more than 3 years

BMI ≥ 30 or ≥ 27 and atleast one comorbidity (hypertension, hypercholesterolemia, microalbuminuria, ischemic heart disease, history of stroke, atherosclerosis or arthrosis

Disqualifiers

Treated with GLP1-RAs within last 6 months

Known intolerance for semaglutide

Other forms of diabetes

Pregnant or nursing women

Trial design

Treatments tested in this trial

  • Semaglutide 2.4mg
  • Semaglutide placebo

Treatment groups

122 Participants
are divided into 2 treatment groups

Locations

1
Nordsjaellands Hospital3400, HillerødDenmark, Denmark

Sponsors and collaborators

Nordsjaellands Hospital

Lead sponsor

Steno Diabetes Center Copenhagen

Collaborator

Steno Diabetes Center Odense

Collaborator

Zealand University Hospital

Collaborator

Aarhus University Hospital

Collaborator