[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100423832":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":65,"collaborators":41,"id":67,"slug":41,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":41,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":41,"maxAge":41,"enrollmentInfo":74,"targetDuration":41,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":48,"whyStopped":41,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Topotecan","ACTIVE_COMPARATOR","Topotecan intraocular injection during chemotherapy",[13],"Drug: Topotecan",{"label":15,"type":16,"description":17,"interventionNames":18},"Melphalan","EXPERIMENTAL","Melphalan intraocular injection during chemotherapy",[19],"Drug: Melphalan",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Topotecan intraocular injection for chemotherapy in retinoblastoma",[9],[26],"Topotecan intraocular injection",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Melphalan intraocular injection for chemotherapy in retinoblastoma",[15],[31],"Melphalan intraocular injection",[33],{"name":34,"affiliation":5,"role":35},"Huashen Yang","PRINCIPAL_INVESTIGATOR",[37,43],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},"Huasheng Yang","CONTACT","+00862087331539",null,"yanghs64@126.com",{"name":44,"role":39,"phone":40,"phoneExt":41,"email":45},"Huijing Ye","yehuijing@qq.com",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Guangzhou","Guangdong","510000","China",{"type":54,"coordinates":55},"Point",[56,57],113.25,23.11667,{"lat":57,"lon":56},[60,63],{"name":61,"role":39,"phone":62,"phoneExt":41,"email":45},"Huijing Ye, Doctor","00862087331539",{"name":64,"role":39,"phone":62,"phoneExt":41,"email":42},"Huasheng Yang, Doctor",{"type":35,"investigatorFullName":38,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"Principal Investigator","100423832",false,"NCT04799002","Topotecan and Melphalan for Retinoblastoma","Choice of Topotecan or Melphalan in Retinoblastoma Patients","Inclusion Criteria:\n\n* diagnosed as retinoblastoma\n* receiving eyeball-sparing treatment\n\nExclusion Criteria:\n\n* disease progression during follow-up","ALL",{"count":75,"type":76},50,"ESTIMATED","INTERVENTIONAL",[79],"PHASE3","The purpose of this study is to evaluate topotecan and melphalan for retinoblastoma patients.",[82,83],"Retinoblastoma","Chemotherapy Effect",[82,85,15],"topotecan","2021-03-12",{"date":88,"type":89},"2021-03-16","ACTUAL",{"date":91,"type":89},"2021-03-11",{"date":93,"type":76},"2027-12-30",{"name":5,"class":6},1]