This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether 2 cycles induction chemotherapy combined with concurrent chemoradiotherapy is not inferior to 3 cycles induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma.
Age 18-65 years old;
Pathologically confirmed non-keratinizing nasopharyngeal carcinoma;
Stage T3-4N0-1 (according to the UICC/AJCC 8th);
No distant metastasis;
The purpose of treatment is palliative;
Diagnosed with other malignant tumors at the same time;
Malignant tumor history;
Pregnancy or breastfeeding, or expect to become pregnant during the clinical trial period;
First Affiliated Hospital, Sun Yat-Sen University
Lead sponsor