Health Trials

Azithromycin for Cerclage Prophylaxis

ConditionCervical Insufficiency
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorWake Forest University Health Sciences

About this trial

The primary goal is to assess the effectiveness in pregnancy prolongation utilizing azithromycin at the time of transvaginal cervical cerclage placement.

Eligibility criteria

Qualifiers

Singleton gestation at 16+0 to 23+6 weeks of gestational age at the time of enrollment

Indication for transvaginal cerclage placement

Intact amniotic membranes

Disqualifiers

Evidence of active infection or chorioamnionitis at presentation

Preterm prelabor rupture of membranes (PPROM)

Multiple gestation

HIV positive status

Trial design

Treatments tested in this trial

  • Azithromycin Prophylaxis
  • Azithromycin Placebo
  • Cefazolin

Treatment groups

80 Participants
are divided into 2 treatment groups

Locations

2
Advocate Christ Medical Center60453, Oak LawnIllinois, United States
Advocate Lutheran General Hospital60068, Park RidgeIllinois, United States

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor

Source ClinicalTrials.gov