[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605562":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":25,"locations":34,"responsibleParty":108,"collaborators":25,"id":111,"slug":25,"hasResults":112,"nctId":113,"briefTitle":114,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":112,"sex":117,"minAge":118,"maxAge":25,"enrollmentInfo":119,"targetDuration":25,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":79,"whyStopped":25,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":139},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Doxycycline group","ACTIVE_COMPARATOR","Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Doxycycline",[13],"Drug: Doxycycline",{"label":15,"type":10,"description":16,"interventionNames":17},"Azithromycin group","Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Azithromycin",[18],"Drug: Azithromycin",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Doxycycline","Subjects will receive Doxycycline (orally or intravenously) in combination with beta-lactam therapy within 12 hours of hospital admission. Treatment duration will be 5-7 days.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Azithromycin","Subjects will receive Azithromycin (orally or intravenously) in combination with beta-lactam therapy within 12 hours of hospital admission. Treatment duration will be 5-7 days.",[15],[31],{"name":32,"affiliation":5,"role":33},"Yewande Odeyemi","PRINCIPAL_INVESTIGATOR",[35,51,64,77,95],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Mayo Clinic in Arizona","NOT_YET_RECRUITING","Scottsdale","Arizona","85259","United States",{"type":43,"coordinates":44},"Point",[45,46],-111.89903,33.50921,{"lat":46,"lon":45},[49],{"name":50,"role":33,"phone":25,"phoneExt":25,"email":25},"Cyril Varghese",{"facility":52,"status":37,"city":53,"state":54,"zip":55,"country":41,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Mayo Clinic in Florida","Jacksonville","Florida","32224",{"type":43,"coordinates":57},[58,59],-81.65565,30.33218,{"lat":59,"lon":58},[62],{"name":63,"role":33,"phone":25,"phoneExt":25,"email":25},"Swetha Reddy",{"facility":65,"status":37,"city":66,"state":67,"zip":68,"country":41,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Mayo Clinic Health System-Mankato","Mankato","Minnesota","56001",{"type":43,"coordinates":70},[71,72],-94.00915,44.15906,{"lat":72,"lon":71},[75],{"name":76,"role":33,"phone":25,"phoneExt":25,"email":25},"Mohamad El Labban",{"facility":78,"status":79,"city":80,"state":67,"zip":81,"country":41,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"Mayo Clinic in Rochester","RECRUITING","Rochester","55905",{"type":43,"coordinates":83},[84,85],-92.4699,44.02163,{"lat":85,"lon":84},[88,93],{"name":89,"role":90,"phone":91,"phoneExt":25,"email":92},"Amy Amsbaugh","CONTACT","507-538-7538","amsbaugh.amy@mayo.edu",{"name":94,"role":33,"phone":25,"phoneExt":25,"email":25},"Yewande Efunpeju Odeyemi",{"facility":96,"status":37,"city":97,"state":98,"zip":99,"country":41,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Mayo Clinic Health System-La Crosse","La Crosse","Wisconsin","54601",{"type":43,"coordinates":101},[102,103],-91.23958,43.80136,{"lat":103,"lon":102},[106],{"name":107,"role":33,"phone":25,"phoneExt":25,"email":25},"Melissa K Myers",{"type":33,"investigatorFullName":109,"investigatorTitle":110,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Yewande Odeyemi, MD","Principal Investigator","100605562",false,"NCT07164131","Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams","AD-CAP","Inclusion Criteria:\n\n• All adult patients (\\>18 years old) admitted with CAP and receiving a beta-lactam antibiotic plus a form of atypical coverage (azithromycin or doxycycline) in the ED within 12 hours of admission.\n\nExclusion Criteria:\n\n* High clinical suspicion for Legionella pneumonia\n* Allergy or contraindication to the use of either azithromycin or doxycycline (usual clinical practice)\n* Antibiotics not for CAP\n* Pregnant women (based on clinical assessment as part of standard of care)\n* Severe CAP as defined by the ATS\u002FIDSA criteria\n* Corrected QT prolongation (\\> 440 ms in men and \\> 460 ms in women)\n* Receiving a different antibiotic (e.g quinolones)\n* Admission \\> 24 hours\n* Known to be a prisoner","ALL","18 Years",{"count":120,"type":121},1120,"ESTIMATED","INTERVENTIONAL",[124],"PHASE4","The purpose of this study is to compare effectiveness and safety of Azithromycin versus Doxycycline in adult patients hospitalized with community acquired pneumonia (CAP) treated with Beta-lactams.",[127],"Community-acquired Pneumonia",[27,22,129],"hospitalized","2026-07-01",{"date":132,"type":133},"2026-07-02","ACTUAL",{"date":135,"type":133},"2025-09-15",{"date":137,"type":121},"2031-09-01",{"name":5,"class":6},5]