[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585562":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":25,"studyPopulation":18,"armGroups":26,"interventions":33,"overallOfficials":41,"centralContacts":46,"locations":55,"responsibleParty":74,"collaborators":76,"id":80,"slug":18,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":18,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":18,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":58,"whyStopped":18,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Boston Medical Center","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Neck circumference","A standard tape measure will be used and circumference recorded in centimeters","Baseline, 4 weeks",[14],{"measure":15,"description":16,"timeFrame":17},"Post injection neck appearance","A 5-item investigator developed questionnaire will be used to assess each participant's opinion about their neck appearance after the botulinum toxin injections. Each item has 4 potential responses from 1=Definitely disagree to 4=Definitely agree. Total scores can range from 5 to 20 and higher scores suggest more positive opinions about their neck appearance.","4 weeks",null,{"allocation":20,"interventionModel":21,"interventionModelDescription":18,"primaryPurpose":22,"observationalModel":18,"timePerspective":18,"maskingInfo":23},"NA","SINGLE_GROUP","TREATMENT",{"masking":24,"maskingDescription":18,"whoMasked":18},"NONE","The specific study objectives are to determine if:\n\n* the neck circumference is decreased at 4 weeks after botulinum toxin (prabotulinumtoxinA-xvfs) injection.\n* patients can appreciate a difference in their neck contour, self-confidence, and the way they perceive themselves post-injection via an aesthetics outcome and a neck perception survey.\n* injection of the botulinum toxin into the sternocleidomastoid muscle is safe to perform based on adverse events.",[27],{"label":28,"type":29,"description":30,"interventionNames":31},"Botulinum injection into SCM","EXPERIMENTAL","All participants will receive bilateral botulinum injections into the SCM.",[32],"Drug: prabotulinumtoxinA-xvfs",[34],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"DRUG","prabotulinumtoxinA-xvfs","Each participant will receive 60 units (U) of prabotulinumtoxinA-xvfs into each SCM for a total of 120 U. Participants will return in 2 weeks to determine if any touch-up injection is needed.",[28],[40],"Jeuveau",[42],{"name":43,"affiliation":44,"role":45},"Jeffrey Spiegel, MD","Boston Medical Center and The Spiegel Center","PRINCIPAL_INVESTIGATOR",[47,51],{"name":43,"role":48,"phone":49,"phoneExt":18,"email":50},"CONTACT","617 566-3223","Jeffrey.Spiegel@bmc.org",{"name":52,"role":48,"phone":53,"phoneExt":18,"email":54},"Amanda Goslawski, MD","617 638-7934","Amanda.Goslawski@bmc.org",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"The Spiegel Center","RECRUITING","Newton","Massachusetts","02459","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-71.20922,42.33704,{"lat":68,"lon":67},[71,73],{"name":43,"role":48,"phone":18,"phoneExt":18,"email":72},"drspiegel@drspiegel.com",{"name":52,"role":48,"phone":18,"phoneExt":18,"email":54},{"type":75,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[77],{"name":78,"class":79},"Evolus, Inc.","INDUSTRY","100585562",false,"NCT06903975","BoTox Into the Sternocleidomastoid Muscles (SCM)","The Effect of Injection of prabotulinumtoxinA-xvfs (Jeuveau) Into the Bilateral Sternocleidomastoid Muscles on Neck Circumference and Aesthetics","Inclusion Criteria:\n\n* Age eligible individual seeking a more feminine neck appearance\n\nExclusion Criteria:\n\n* Prior neuromodulator injections in the sternocleidomastoid muscles (SCM) within the past year\n* Current anticoagulant use\n* Body mass index (BMI) \\>30\n* Anticipation of significant weight gain or loss during the study period (e.g. patients taking or planning to take within the study period a semaglutide medication.)\n* Prior allergy to botulinum toxin A\n* Currently pregnant or breastfeeding",true,"ALL","18 Years","65 Years",{"count":91,"type":92},30,"ESTIMATED","INTERVENTIONAL",[95],"PHASE4","Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary slimming effect on the neck and produce a more feminine, youthful neck contour.",[98],"Neck Muscle Issue",[10,100,101,102,103],"Neck aesthetics","Sternocleidomastoid muscles (SCM)","Botulinum injection","PrabotulinumtoxinA-xvfs injection","2026-04-14",{"date":106,"type":107},"2026-04-17","ACTUAL",{"date":109,"type":107},"2025-05-14",{"date":111,"type":92},"2026-08",{"name":5,"class":6},1]