Health Trials

About this trial

This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated. Patients managed with three different anesthesia methods currently used will be examined for recovery patterns:

1. Total intravenous anesthesia (TIVA), 2. TIVA Combined anesthesia with sevoflurane and intravenous agents (sevoflurane-CIVIA), 3. TIVA Combined anesthesia with desflurane and intravenous agents (desflurane-CIVIA).

Recovery patterns include; extubation time, eye opening time, emergence agitation, postoperative nausia and vomiting and postoperative recovery unit discharge time.

Eligibility criteria

Qualifiers

Scheduled for spine surgery

Expected surgery duration longer than 3 hours

Use of intraoperative neuromonitoring

BIS-guided anesthesia administered

Disqualifiers

Emergency surgeries

Patients receiving sole inhaled anesthesia (no TIVA)

Perioperative dural injury

Intraoperative severe hypotension requiring inotropic support

Trial design

Treatments tested in this trial

  • Sevofluorane
  • Desflurane
  • Total Intravenous Anesthesia(TIVA)

Treatment groups

210 Participants
are divided into 3 treatment groups

Locations

1
Kocaeli City HospitalYozgat, KocaeliIzmıt, Turkey (Türkiye)

Sponsors and collaborators

Kocaeli City Hospital

Lead sponsor

Source ClinicalTrials.gov