[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604763":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":38,"locations":44,"responsibleParty":63,"collaborators":65,"id":280,"slug":37,"hasResults":281,"nctId":282,"briefTitle":283,"officialTitle":284,"acronym":285,"eligibilityCriteria":286,"healthyVolunteers":281,"sex":287,"minAge":288,"maxAge":37,"enrollmentInfo":289,"targetDuration":37,"studyType":292,"phases":293,"briefSummary":295,"conditions":296,"keywords":299,"overallStatus":307,"whyStopped":37,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":312,"completionDateStruct":314,"leadSponsor":316,"locationsCount":317},{"fullName":5,"class":6},"Shanghai Hutchison Pharmaceuticals Limited","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"the Shexiang Baoxin Pill Group","EXPERIMENTAL","Patients in the Shexiang Baoxin Pill group initiated treatment immediately after randomization. They received 2-4 pills of Shexiang Baoxin Pill preoperatively before PCI, followed by a maintenance dose of 2-4 pills orally three times daily (TID) with warm water for 12 months postoperatively, concurrently with standard guideline-directed therapy.",[13],"Drug: Shexiang Baoxin Pill",{"label":15,"type":16,"description":17,"interventionNames":18},"the Conventional Treatment Group","ACTIVE_COMPARATOR","Patients in the conventional treatment group will receive standard treatment in accordance with guidelines and consensuses after surgery, and this will last for 12 months.",[19],"Drug: Aspirin",[21,34],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Aspirin","Patients in the Shexiang Baoxin Pill(MUSKARDI) group initiated treatment immediately after randomization. They received 2-4 pills of Shexiang Baoxin Pill preoperatively before PCI, followed by a maintenance dose of 2-4 pills orally three times daily (TID) with warm water for 12 months postoperatively, concurrently with standard guideline-directed therapy.",[15],[27,28,29,30,31,32,33],"standard guideline-directed therapy","ABCDE","Antiplatelet","Beta-blocker","Cholesterol","Diet & Diabetes","Education & Exercise",{"type":22,"name":35,"description":11,"armGroupLabels":36,"otherNames":37},"Shexiang Baoxin Pill",[9],null,[39],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Fang Wang, of Medicine (M.Med.)","CONTACT","+86 13818403261","wangfang@shpl.com.cn",[45],{"facility":46,"status":37,"city":47,"state":37,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Zhongshan Hospital, Fudan University","Shanghai","200032","China",{"type":51,"coordinates":52},"Point",[53,54],121.45806,31.22222,{"lat":54,"lon":53},[57,61],{"name":58,"role":41,"phone":59,"phoneExt":37,"email":60},"Hongbo Yang, doctorate in medicine","+86 13585890793","yang.hongbo@zs-hospital.sh.cn",{"name":62,"role":41,"phone":37,"phoneExt":37,"email":37},"Jing min Zhou, doctorate in medicine",{"type":64,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR",[66,69,71,73,75,77,79,81,83,85,87,89,91,93,95,98,101,103,105,107,109,111,113,115,117,119,121,123,126,128,130,132,134,136,138,140,142,144,146,148,150,152,154,156,158,160,162,164,166,168,170,172,174,176,178,180,182,184,186,188,190,192,194,196,198,200,202,204,206,208,210,212,214,216,218,220,222,224,226,228,230,232,234,236,238,240,242,244,246,248,250,252,254,256,258,260,262,264,266,268,270,272,274,276,278],{"name":67,"class":68},"Shanghai Zhongshan Hospital","OTHER",{"name":70,"class":68},"Huashan Hospital",{"name":72,"class":68},"Shanghai 10th People's Hospital",{"name":74,"class":68},"Shanghai 6th People's Hospital",{"name":76,"class":68},"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine",{"name":78,"class":68},"Shanghai East Hospital",{"name":80,"class":68},"Longhua Hospital",{"name":82,"class":68},"Second Affiliated Hospital of Soochow University",{"name":84,"class":68},"Affiliated Hospital of Jiangsu University",{"name":86,"class":68},"The First Affiliated Hospital with Nanjing Medical University",{"name":88,"class":68},"The First People's Hospital of Lianyungang",{"name":90,"class":68},"Huai'an First People's Hospital",{"name":92,"class":68},"Sir Run Run Shaw Hospital",{"name":94,"class":68},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"name":96,"class":97},"First Affiliated Hospital of Ningbo University","NETWORK",{"name":99,"class":100},"Shandong Provincial Hospital","OTHER_GOV",{"name":102,"class":68},"Qianfoshan Hospital",{"name":104,"class":68},"Weihai Municipal Hospital",{"name":106,"class":68},"Weifang People's Hospital",{"name":108,"class":68},"Rizhao People's Hospital",{"name":110,"class":68},"The Affiliated Hospital of Qingdao University",{"name":112,"class":68},"Jining First People's Hospital",{"name":114,"class":68},"Linyi People's Hospital",{"name":116,"class":68},"Xiangya Hospital of Central South University",{"name":118,"class":68},"Second Xiangya Hospital of Central South University",{"name":120,"class":68},"Yueyang Central Hospital",{"name":122,"class":68},"The First Affiliated Hospital of University of South China",{"name":124,"class":125},"The Central Hospital of Shaoyang","UNKNOWN",{"name":127,"class":68},"The First People's Hospital of Changde City",{"name":129,"class":68},"Wuxi People's Hospital",{"name":131,"class":68},"Jinhua Central Hospital",{"name":133,"class":68},"The Third Affiliated Hospital of Wenzhou Medical University",{"name":135,"class":125},"Shuguang Hospital of Shanghai University of Traditional Chinese Medicine",{"name":137,"class":68},"Affiliated Hospital of Shandong University of Traditional Chinese Medicine",{"name":139,"class":68},"ZhuZhou Central Hospital",{"name":141,"class":68},"First People's Hospital of Chenzhou",{"name":143,"class":68},"People's Hospital of Quzhou",{"name":145,"class":125},"Xuzhou New Health Hospital",{"name":147,"class":68},"Taizhou Enze Medical Center Group",{"name":149,"class":68},"Beijing Chao Yang Hospital",{"name":151,"class":68},"Civil Aviation General Hospital",{"name":153,"class":68},"Xuanwu Hospital, Beijing",{"name":155,"class":68},"Beijing Friendship Hospital",{"name":157,"class":68},"Peking University People's Hospital",{"name":159,"class":68},"Beijing Electric Power Hospital",{"name":161,"class":68},"Renmin Hospital of Wuhan University",{"name":163,"class":68},"Wuhan No.1 Hospital",{"name":165,"class":68},"Jingzhou Central Hospital",{"name":167,"class":68},"The First Affiliated Hospital of Dalian Medical University",{"name":169,"class":125},"Ansteel Group General Hospital",{"name":171,"class":125},"General Hospital of Fuxin Mining Industry Group of Liaoning Health Industry Group",{"name":173,"class":68},"The First Affiliated Hospital of Zhengzhou University",{"name":175,"class":68},"Huaihe Hospital of Henan University",{"name":177,"class":68},"Zhoukou Central Hospital",{"name":179,"class":68},"The First Affiliated Hospital of Henan University of Science and Technology",{"name":181,"class":68},"First Affiliated Hospital of Nanyang Medical College",{"name":183,"class":125},"Jiaozuo Second People's Hospital",{"name":185,"class":125},"Anyang Area Hospital of Puyang City",{"name":187,"class":68},"Shijiazhuang People's Hospital",{"name":189,"class":68},"Cangzhou Central Hospital",{"name":191,"class":68},"The First Hospital of Hebei Medical University",{"name":193,"class":68},"Handan Central Hospital",{"name":195,"class":125},"The People's Hospital of Langfang City",{"name":197,"class":125},"Xingtai Central Hospital",{"name":199,"class":68},"North China University of Science and Technology",{"name":201,"class":68},"The First Affiliated Hospital of Anhui Medical University",{"name":203,"class":125},"the First Hospital of Anhui University of Science and Technology",{"name":205,"class":68},"Chaohu Hospital of Anhui Medical University",{"name":207,"class":100},"Tongling People's Hospital",{"name":209,"class":68},"Huang Shan People's Hospital",{"name":211,"class":125},"Huaibei Miners General Hospital",{"name":213,"class":68},"The Second Affiliated Hospital of Fujian Medical University",{"name":215,"class":68},"Changzhi Medical College",{"name":217,"class":125},"LinFen People's Hospital",{"name":219,"class":68},"Shanxi Cardiovascular Hospital",{"name":221,"class":125},"Dazhou First People's Hospital",{"name":223,"class":68},"The Affiliated Hospital Of Southwest Medical University",{"name":225,"class":68},"The Third Affiliated Hospital of Guangzhou Medical University",{"name":227,"class":68},"The First Affiliated Hospital of Guangdong Pharmaceutical University",{"name":229,"class":125},"Yangchun People's Hospital",{"name":231,"class":125},"Shaoguan People's Hospital",{"name":233,"class":125},"Guilin People's Hospital",{"name":235,"class":68},"The First Affiliated Hospital of Nanchang University",{"name":237,"class":125},"Ji'an Central People's Hospital",{"name":239,"class":68},"Jiangxi Provincial People's Hopital",{"name":241,"class":68},"People's Hospital of Chongqing",{"name":243,"class":68},"Ankang Central Hospital",{"name":245,"class":68},"Xiangyang Central Hospital",{"name":247,"class":68},"Tianjin Third Central Hospital",{"name":249,"class":68},"General Hospital of Ningxia Medical University",{"name":251,"class":68},"The Second Affiliated Hospital of Hainan Medical University",{"name":253,"class":68},"Lanzhou University Second Hospital",{"name":255,"class":125},"Jilin Province People's Hospital",{"name":257,"class":125},"Inner Mongolia Autonomous Region People's Hospital",{"name":259,"class":68},"Yan'an Affiliated Hospital of Kunming Medical University",{"name":261,"class":125},"The People's Hospital of Jizhou District, Tianjin",{"name":263,"class":125},"The Southwest Hospital of Army Medical University",{"name":265,"class":125},"The First People's Hospital of Nanning",{"name":267,"class":125},"The People' s Hospital of Jiangmen",{"name":269,"class":125},"The second People's Hospital of Guiyang",{"name":271,"class":68},"The Third People's Hospital of Chengdu",{"name":273,"class":125},"The Tirst People's Hospital of Mianyang",{"name":275,"class":68},"First Affiliated Hospital of Fujian Medical University",{"name":277,"class":125},"The First People's Hospital of Chu Zhou",{"name":279,"class":68},"Xuancheng People's Hospital","100604763",false,"NCT07153744","Efficacy and Safety of Shexiang Baoxin Pill(MUSKARDIA) in the Treatment of Acute Myocardial Infarction","Efficacy and Safety of Shexiang Baoxin Pill(MUSKARDIA) in the Treatment of Acute Myocardial Infarction: A Prospective, Multicenter, Pragmatic Randomized Controlled Real-World Study","MUST Ⅱ","Inclusion Criteria:\n\n* Aged 18 years or older, regardless of gender\n* In accordance with the 2023 ESC Guidelines for the Management of Acute Coronary Syndromes , meeting the diagnostic criteria for acute myocardial infarction, including typical chest pain lasting for ≥20 minutes, electrocardiographic manifestations of ST-segment elevation (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI), and serum high-sensitivity troponin (hs-cTn) levels exceeding the 99th percentile of the upper reference limit at least once with dynamic changes\n* Presenting for treatment within \\\u003C24 hours of symptom onset and scheduled to undergo PCI\n* The patient or their guardian has signed the informed consent form\n\nExclusion Criteria:\n\n* Having contraindications to PCI treatment\n* Being allergic to Shexiang Baoxin Pills, unable to tolerate them, or having other conditions that prevent completion of the trial drug administration\n* Being pregnant, planning to become pregnant, or breastfeeding women\n* Having participated in other clinical studies within 3 months\n* Being deemed unsuitable for inclusion in this study by the researcher","ALL","18 Years",{"count":290,"type":291},9588,"ESTIMATED","INTERVENTIONAL",[294],"PHASE4","This study aims to evaluate the value of Shexiang Baoxin Pill (MUSKARDIA) in patients with acute myocardial infarction (AMI) through a prospective, multicenter, pragmatic randomized controlled real-world study. It seeks to validate its efficacy in reducing cardiovascular event risk during the peri-PCI period, as well as its effects on cardiac function, quality of life , and relevant biomarkers. Through this research, we expect to provide higher-quality evidence for the application of SBP in AMI patients undergoing PCI, thereby further optimizing comprehensive treatment strategies for AMI.",[297,298],"Acute Myocardial Infarction (AMI)","Percutaneous Coronary Intervention (PCI)",[300,301,302,303,35,304,305,306],"Acute Myocardial Infarction","AMI","Percutaneous Coronary Intervention","PCI","MUSKARDIA","Shexiang Baoxin Pill(MUSKARDIA)","SBP","NOT_YET_RECRUITING","2025-08-26",{"date":310,"type":311},"2025-09-04","ACTUAL",{"date":313,"type":291},"2025-09-01",{"date":315,"type":291},"2029-12-31",{"name":5,"class":6},1]