The purpose of this study is:
1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. 2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. 3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.
Age between 35-65 years old, male or female;
Grade 1 essential hypertension;
Taking no antihypertensive drugs or taking antihypertensive drugs irregularly in the past ;
Sign the informed consent;
Significant liver and kidney dysfunction, ALT and AST upper the twice of normal range, Scr≥2.0mg/dl, eGFR<60ml/(min·1. 73m2);
Gastrointestinal diseases, which may affect drug absorption;
Be allergic to the clinical trial medicine;
Pregnant or breastfeeding women, men who plan to give birth within half a year;
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Lead sponsor
Suzhou Hosptial of Traditional Chinese Medicine
Collaborator
Shandong University of Traditional Chinese Medicine
Collaborator