Gag Therapy for Recurrent Urinary Tract Infection Assessing Comparability to International Nitrofurantoin Gold Standard Study

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorRadboud University Medical Center

About this trial

The GT RACING is a study comparing the efficacy of HA-CS bladder installations with prophylactic antibiotics in the prevention of recurrent urinary tract infections (rUTI).

Eligibility criteria

Qualifiers

Adult female patients (>18 years) who had at least 3 symptomatic UTI's in the previous year with no adequate curable therapeutic options (e.g. bladder stones)

At least one UTI's must be confirmed with a positive culture and antibiogram, further UTI's must be confirmed with a urine sediment with positive nitrite or a positive culture.

Disqualifiers

Male

< 18 years

Pregnant

Already on GAG therapy

Trial design

Treatments tested in this trial

  • Ialuril 50ml Prefill
  • Nitrofurantoin

Treatment groups

100 Participants
are divided into 2 treatment groups

Locations

3
Radboudumc6525 GA, NijmegenGelderland, Netherlands
Rijnstate ziekenhuis Arnhem Netherlands
Canisius wilhelmina ziekenhuis Nijmegen Netherlands

Sponsors and collaborators

Radboud University Medical Center

Lead sponsor

IBSA Institut Biochimique SA

Collaborator

Goodlife Pharma B.V.

Collaborator