Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
ConditionOsteoarthritis Thumb
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age40-85
SponsorDiakonhjemmet Hospital
About this trial
A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis
Eligibility criteria
Qualifiers
OA confirmed by radiographs or ultrasound examination, and
Inflammation by ultrasound (grey scale synovitis grade 1-3), and
Pain of at least 3 on a 0-10 Numeric Rating Scale (NRS) at rest or during activities at both pre-screening and screening.
Patient is assessed as eligible for the proposed use of Kenacort-T
Disqualifiers
Use of thumb orthosis on most of the days or structured hand exercises in the last 12 weeks
Intraarticular injections in the target CMC-1 joint in the last 12 weeks
More than 3 previous IACS in the target CMC-1 joint
Use of oral, intramuscular or intravenous steroids in the last 12 weeks
Trial design
Treatments tested in this trial
- Injection of triamcinolone acetonide into the CMC-1 joint
- Multimodal Occupational therapy for CMC-1 joint OA
- Placebo
Treatment groups
354 Participants
are divided into 3 treatment groupsLocations
6Nordlands Hospital Bodø Norway
Haugesund Rheumatism Hospital Haugesund Norway
Diakonhjemmet Hospital Oslo Norway
Martina Hansens Hospital Sandvika Norway
Sponsors and collaborators
Diakonhjemmet Hospital
Lead sponsor
Vestre Viken Hospital Trust
Collaborator
Helse Stavanger HF
Collaborator
Haugesund Rheumatism Hospital
Collaborator
St. Olavs Hospital
Collaborator
Nordlandssykehuset HF
Collaborator
Source ClinicalTrials.gov