The purpose of this study is to determine the effectiveness of prophylactic administration of intra-thecal nicardipine though lumbar cerebrospinal fluid drain in prevention of symptomatic vasospasm in patients with subarachnoid hemorrhage due to rupture of cerebral aneurysms.
Age ≥18 years
Aneurysmal subarachnoid hemorrhage with Hunt and Hess score 3 or less
Patient or legal authorized representative available to sign the informed consent form
Pre-morbid modified Rankin scale of 0 or 1.
Pregnant females
Subarachnoid hemorrhage (SAH) with hunt and hess scale of >3
SAH due to etiology other than aneurysmal rupture
Any contraindications in patients receiving calcium channel antagonists like hypersensitivity to dihydropyridines
Wake Forest University Health Sciences
Lead sponsor