[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100470940":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":37,"responsibleParty":89,"collaborators":93,"id":104,"slug":31,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":31,"eligibilityCriteria":109,"healthyVolunteers":105,"sex":110,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":31,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":40,"whyStopped":31,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"Nationwide Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental","EXPERIMENTAL","This is a one-arm study and the group of subjects are all experimental and will receive drug.",[13],"Drug: Prednisolone",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Prednisolone","Liquid, 5mg\u002Fkg per week, for one year",[9],[21],"Corticosteroid",[23],{"name":24,"affiliation":5,"role":25},"Anne Connolly, MD","PRINCIPAL_INVESTIGATOR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Sara Marshall","CONTACT","614-355-3508",null,"sara.adamczak@nationwidechildrens.org",{"name":34,"role":29,"phone":35,"phoneExt":31,"email":36},"Kevin Warf","614-355-2765","kevin.warf@nationwidechildrens.org",[38,51,61,74],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":31},"Lurie Children's Hospital of Chicago","RECRUITING","Chicago","Illinois","60611","United States",{"type":46,"coordinates":47},"Point",[48,49],-87.65005,41.85003,{"lat":49,"lon":48},{"facility":52,"status":40,"city":53,"state":54,"zip":55,"country":44,"cosmosGeoPoint":56,"geoPoint":60,"contacts":31},"University of Cincinnati","Cincinnati","Ohio","45220",{"type":46,"coordinates":57},[58,59],-84.51439,39.12711,{"lat":59,"lon":58},{"facility":5,"status":40,"city":62,"state":54,"zip":63,"country":44,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Columbus","43205",{"type":46,"coordinates":65},[66,67],-82.99879,39.96118,{"lat":67,"lon":66},[70,73],{"name":71,"role":29,"phone":72,"phoneExt":31,"email":36},"Kevin Warf, BS","(614) 355-2765",{"name":24,"role":25,"phone":31,"phoneExt":31,"email":31},{"facility":75,"status":40,"city":76,"state":77,"zip":78,"country":44,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"University of Texas Southwestern","Dallas","Texas","75235",{"type":46,"coordinates":80},[81,82],-96.80667,32.78306,{"lat":82,"lon":81},[85],{"name":86,"role":29,"phone":87,"phoneExt":31,"email":88},"Shahera Ranjha, MS","214-456-5959","shahera.ranjha@utsouthwestern.edu",{"type":90,"investigatorFullName":91,"investigatorTitle":92,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"SPONSOR_INVESTIGATOR","Anne M. Connolly","Chief of Division of Neurology",[94,96,98,100,102],{"name":95,"class":6},"Children's Hospital Medical Center, Cincinnati",{"name":97,"class":6},"Muscular Dystrophy Association",{"name":99,"class":6},"University of Texas",{"name":101,"class":6},"Virginia Commonwealth University",{"name":103,"class":6},"Ann & Robert H Lurie Children's Hospital of Chicago","100470940",false,"NCT05412394","Once Weekly Infant Corticosteroid Trial for DMD","Phase-2 Trial of 5mg\u002Fkg\u002FWeek Prednisolone in Young Boys With DMD","Inclusion Criteria:\n\n* Subjects ages 1 month through 30 months\n* Weakness consistent with Duchenne on exam, creatine kinase ≥ 20 times the upper limit of normal, and genetic mutation known to be causative for DMD.\n\nExclusion Criteria:\n\n* Prior treatment with Glucocorticosteroids","MALE","1 Month","30 Months",{"count":114,"type":115},26,"ESTIMATED","INTERVENTIONAL",[118],"PHASE4","The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg\u002Fkg\u002Fweek) will be equally effective to the 10mg\u002Fkg\u002Fweek dose.",[121],"Duchenne Muscular Dystrophy",[121,123,124,125],"DMD","Steroid","Muscular Dystrophy","2025-08-08",{"date":128,"type":129},"2025-08-13","ACTUAL",{"date":131,"type":129},"2021-04-30",{"date":133,"type":115},"2026-12",{"name":91,"class":6},4]