The purpose of our study is to evaluate the efficacy and safety of different volumes of bladder-numbing medication for pain relief at the time of office bladder Botox injections. This is a randomized prospective, double-blind superiority trial comparing 200 ml 2% lidocaine versus 30 ml 2% lidocaine for office Botox injections.
Adult female, >18 years, English-speaking (surveys utilized are not validated in all languages)
Able to provide informed consent
Indications: Refractory urge urinary incontinence, Refractory urinary urgency and frequency, Neurogenic bladder (without sensory deficit)
Untreated urinary tract infection at the time of procedure
Contra-indication to Botox
Contraindication to intravesical lidocaine
Inability to provide informed consent
University of Louisville
Lead sponsor