The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
Age >= 3 and < 18 years
Elective tonsillectomy +/- adenoidectomy
Signed informed consent by parent or legal guardian
Children >= 12 years must provide signed written consent, Children >= 7 years must provide verbal assent
History of chronic kidney or liver disease
Current diagnosis of a chronic pain disorder
Planned admission to the Pediatric Intensive Care Unit (PICU)
Additional procedures under general anesthesia for which opioids would be prescribed
Duke University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator