Preoperative Acetazolamide
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age21-65
SponsorPrisma Health-Upstate
About this trial
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.
Eligibility criteria
Qualifiers
Women
Ages 21-65
undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without bilateral salpingoophorectomy
undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without cystoscopy
Disqualifiers
Allergy to acetazolamide or sulfonamides
Known electrolyte disturbances
Pregnancy
Kidney failure or creatinine >1.5
Trial design
Treatments tested in this trial
- Acetazolamide 500 MG Extended Release Oral Capsule
- Placebo
Treatment groups
100 Participants
are divided into 2 treatment groupsLocations
1Prisma Health29605, GreenvilleSouth Carolina, United States
Sponsors and collaborators
Prisma Health-Upstate
Lead sponsor
Source ClinicalTrials.gov