[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565768":3},{"organization":4,"outcomesModule":7,"designInfo":77,"detailedDescription":80,"studyPopulation":80,"armGroups":84,"interventions":92,"overallOfficials":107,"centralContacts":112,"locations":122,"responsibleParty":648,"collaborators":80,"id":650,"slug":80,"hasResults":651,"nctId":652,"briefTitle":653,"officialTitle":654,"acronym":655,"eligibilityCriteria":656,"healthyVolunteers":651,"sex":657,"minAge":658,"maxAge":80,"enrollmentInfo":659,"targetDuration":80,"studyType":662,"phases":663,"briefSummary":665,"conditions":666,"keywords":80,"overallStatus":125,"whyStopped":80,"lastUpdateSubmitDate":669,"lastUpdatePostDateStruct":670,"startDateStruct":673,"completionDateStruct":675,"leadSponsor":677,"locationsCount":679},{"fullName":5,"class":6},"Groupe Francais De Pneumo-Cancerologie","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":72},[9],{"measure":10,"description":11,"timeFrame":12},"Progression Free Survival (PFS)","The Progression Free Survival is defined as the time between treatment start date and event date defined by the Response Evaluation Criteria in Solid Tumor (RECIST) 1.1 progression or death for any cause, whichever comes first.\n\nDisease progression will be evaluated according to (RECIST) 1.1 assessed locally. Frequency of this assessment is let to the investigator \\'s discretion and local practices.\n\nThe participants will be followed until disease progression or death for any cause. Patients without an event at the time of analysis will be censored at the date of their last tumor assessment.","From the date of first dose of treatment received until the date of the first documented disease progression according to Response Evaluation Criteria in Solid Tumor (RECIST) 1.1 or to death from any cause, whichever comes first, assessed up to 2 years",[14,17,21,25,29,33,37,41,45,48,51,54,58,62,65,69],{"measure":15,"description":16,"timeFrame":12},"Objective Response Rate (ORR)","The objective response rate (ORR) is defined as the proportion of patients with complete response (CR) or partial response (PR) as the best response during the study according to RECIST 1.1 criteria based on tumoral assessment performed by thorax-abdominal-pelvic and brain CT scans. The frequency of the tumor assessments will follow the site practices.",{"measure":18,"description":19,"timeFrame":20},"Overall Survival (OS)","Overall survival (OS) is calculated as the time between the date of treatment initiation and date of death, and censored at date of last news for patients alive at the end of the study.","From the treatment start date up to the date of death for a 2-year-period maximum",{"measure":22,"description":23,"timeFrame":24},"Duration of Response (DOR)","The duration of response is defined as the time between the date of the first response assessed by RECIST 1.1 to the date of progression or death for any cause, whichever comes first, and censored at the date of last tumor evaluation for patients still responding to treatment at the end of the study (after 2 years).","From the date of the first response to the date of progression or death, whichever comes first, or for a 2-year-period maximum",{"measure":26,"description":27,"timeFrame":28},"Time to Response (TTR)","Time to response is measured from the date of treatment initiation to the date of first response as defined by RECIST 1.1.","From the start date of treatment up to the date of first response or for a 2-year-period maximum",{"measure":30,"description":31,"timeFrame":32},"Treatment Duration","The duration of treatment is defined as the time between the treatment start date and the date of definitive cessation of treatment, whatever the cause.","From the treatment start date and the treatment stop date whatever the cause up to a 2-year-period maximum.",{"measure":34,"description":35,"timeFrame":36},"Safety events","All adverse events experienced by the participants, whatever the grades of toxicity, will be collected according to CTCAE v4.0 (common terminology criteria for adverse events).","From the enrollment up to the participants study end date or for a 2-year-period maximum",{"measure":38,"description":39,"timeFrame":40},"Treatments description","The treatments for NSCLC will be described including the adaptations: discontinuations, treatment interruptions, dose adaptations. The reasons for the changes will be recorded.","From the start date of the NSCLC treatment up to the participant study end date or for a 2-year-period maximum",{"measure":42,"description":43,"timeFrame":44},"Geriatric interventions: specialized consultations","The specialized geriatric consultations carried out to correct frailties will be collected during the study participation including psychological and\u002For dietetic consultations.","From the enrollment up to the participant study end date or for a 2-year-period maximum",{"measure":46,"description":47,"timeFrame":44},"Geriatric interventions: specialized exercises","The specialized geriatric exercises carried out to correct frailties will be collected during the study participation including prescription of adapted physical activity and\u002For cognitive stimulation exercises.",{"measure":49,"description":50,"timeFrame":44},"Geriatric interventions: specialized help at home","The specialized geriatric interventions at home carried out to correct frailties will be collected during the study participation including home visits by a nurse or home help.",{"measure":52,"description":53,"timeFrame":44},"Geriatric interventions: specialized medications","The specialized geriatric medications carried out to correct frailties will be collected during the study participation.",{"measure":55,"description":56,"timeFrame":57},"European Organisation for Research and Treatment of Cancer Core Function Questionnaire (QLQ-F17)","The QLQ-F17 is a validated cancer-specific questionnaire specific to cancer. It includes 17 items to assess 6 QoL scales: 1 global health scale and 5 functional scales (physical, role,emotional, cognitive, social). This is a shortened version of the QLQ-C30, containing only the functional and overall quality of life sections. This questionnaire was developed by the EORTC in order to optimize the collection of quality-of-life data, and to avoid overloading the patient with a lengthy questionnaire.\n\nSymptoms will be assessed via modules. A score is generated for each dimension and standardized on a scale from 0 to 100, so that a high score reflects a high overall health status, a high functional level and a high symptomatic level. According to EORTC recommendations, the score can be calculated if at least 50% of the items in the corresponding dimension have been completed. Otherwise, the score will be considered missing.","At enrolment, at 12 weeks, at 6 months and at 12 months.",{"measure":59,"description":60,"timeFrame":61},"European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-ELDerly 14 (QLQ-ELD14)","The QLQ-ELD14 questionnaire is specific to elderly cancer patients. It contains 14 items measuring 7 dimensions of quality of life : two functional dimensions (maintaining a positive positive vision\u002Fmotivation, family support) and 5 symptomatic dimensions (mobility, worries about others, worries about the future, disease burden, joint problems).\n\nAll of the scales and single-item range in score from 0-100. A score is generated for each dimension, so that a high score reflects a high functional level (for the scales concerned), and a high symptomatic level (for the scales concerned).","At enrolment, at 12 weeks, at 6 months and at 12 months",{"measure":63,"description":64,"timeFrame":61},"European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13)","The QLQ-LC13 is a lung cancer-specific questionnaire containing 13 items to assess symptoms specific to lung cancer and its treatment: dyspnea, cough, hemoptysis, sore mouth, dysphagia, peripheral neuropathy, alopecia, chest pain, arm or shoulder pain or shoulder pain, pain in other parts, anti-inflammatory drugs, drugs for pain. A score is generated per dimension so that a high score reflects a high symptomatic level.\n\nAll of the scales and single-item range in score from 0-100. A high scale score represents a higher response level.\n\nThus a high score for a functional scale represents a high\u002Fhealthy level of functioning, a high score for the global health status represents a high quality of life, but a high score for symptom scale\u002Fitem represents a high level of symptomatology\u002Fproblems.",{"measure":66,"description":67,"timeFrame":68},"Geriatric characteristics G8 score","The following geriatric characteristics will be collected is available in the participant medical file: G8 score.\n\nThe total G-8 score lies between 0 and 17. A higher score indicates a better health status.","At enrollment and at disease progression for a maximum of 2-year-period.",{"measure":70,"description":71,"timeFrame":68},"Geriatric characteristics Geriatric Core DatasEt (G-CODE)","The following geriatric characteristics will be collected is available in the participant medical file: Geriatric Core DatasEt (G-CODE). G-CODE is a core set of geriatric data. It has ten tools\u002Fitems and a median completion time of 9 min. It includes Katz autonomy scale (ADL), Instrumental Activities of Daily Living (IADL), Charlson score, mini Geriatric Depression Sale (mini-GDS), short cognitive impairment screening exam (mini COG), falls history, Timed Get Up and Go test, social environment.\n\nThe G-CODE allows for a minimal geriatric description of the older cancer population and standardisation of geriatric data, enabling comparison across trials.",[73],{"measure":74,"description":75,"timeFrame":76},"Biobank sampling","Blood samples will be collected at inclusion, before the first administration of NSCLC therapy, for exploratory analyses in ancillary studies","At inclusion",{"allocation":78,"interventionModel":79,"interventionModelDescription":80,"primaryPurpose":81,"observationalModel":80,"timePerspective":80,"maskingInfo":82},"NA","SINGLE_GROUP",null,"BASIC_SCIENCE",{"masking":83,"maskingDescription":80,"whoMasked":80},"NONE",[85],{"label":86,"type":6,"description":87,"interventionNames":88},"Real world cohort of NSCLC older adults patients","Cohort of patients ≥70 years of age with NSCLC treated in first line therapy for thoracic tumors according to ESMO-referenced therapeutic standards or according to an innovative molecule and\u002For strategy.\n\nAn optional biobank based on blood samples taken during the screening phase prior to the first administration of systemic treatment will be collected. Sampling of tumoral materials will be collected prior to study participation and send for central reading.\n\nPatients will be asked to come at the hospital for their regular visits as per site current practice and to complete three quality of life questionnaires (EORTC QLQ-F17; QLQ-LC13; QLQ-ELD14).",[89,90,91],"Genetic: Bio-bank repository","Other: Quality of Life (QoL)","Procedure: G-Code",[93,98,102],{"type":94,"name":95,"description":96,"armGroupLabels":97,"otherNames":80},"GENETIC","Bio-bank repository","Blood samples taken during the screening phase prior to the first administration of systemic treatment and stored in a repository for a maximum duration of 10 years",[86],{"type":6,"name":99,"description":100,"armGroupLabels":101,"otherNames":80},"Quality of Life (QoL)","Collection of EORTC QoL questionnaires QLQ-F17, QLQ-LC13 and QLQ-ELD14:\n\n* stage 3 non-operable\u002Fnon-radiable, stage 4: at inclusion, 12 weeks, 6 months of treatment, first-line progression.\n* operable stage 1 to 3b: at inclusion, end of neoadjuvant period before surgery post-operative baseline, at 6 months, at 12 months.\n* radiable stages 3a to 3c: at inclusion, at the end of thoracic radiotherapy, at 6 months, at 12 months.",[86],{"type":103,"name":104,"description":105,"armGroupLabels":106,"otherNames":80},"PROCEDURE","G-Code","G-CODE: Katz Autonomy Scale (ADL), Instrumental Activities of Daily Living questionnaire (IADL), Charlson score, mini GDS, mini COG, falls history, Timed Get Up and Go test, social environment.",[86],[108],{"name":109,"affiliation":110,"role":111},"Laurent GREILLIER, Professor","Groupe Français de Pneumo-Cancérologie (GFPC)","STUDY_CHAIR",[113,118],{"name":114,"role":115,"phone":116,"phoneExt":80,"email":117},"Romain CORRE, Medical Doctor","CONTACT","+330298526404","romain.corre@ch-cornouaille.fr",{"name":119,"role":115,"phone":120,"phoneExt":80,"email":121},"Soizic FERLANDIN","+330663224789","soizic_ferlandin@yahoo.fr",[123,140,153,163,177,190,203,216,229,242,255,268,281,294,307,320,333,346,359,372,385,398,408,421,434,447,460,470,483,496,508,521,534,547,560,573,586,599,612,622,635],{"facility":124,"status":125,"city":126,"state":80,"zip":127,"country":128,"countryCode":129,"cosmosGeoPoint":130,"geoPoint":135,"contacts":136},"CH du Pays d Aix","RECRUITING","Aix-en-Provence","13616","France","FR",{"type":131,"coordinates":132},"Point",[133,134],5.44973,43.5283,{"lat":134,"lon":133},[137],{"name":138,"role":115,"phone":80,"phoneExt":80,"email":139},"Stéphanie MARTINEZ","smartinez@ch-aix.fr",{"facility":141,"status":125,"city":142,"state":80,"zip":143,"country":128,"countryCode":129,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Hôpital Henri Duffaut","Avignon","84000",{"type":131,"coordinates":145},[146,147],4.80892,43.94834,{"lat":147,"lon":146},[150],{"name":151,"role":115,"phone":80,"phoneExt":80,"email":152},"Nicolas CLOAREC","clarec.nicolas@ch-avignon.fr",{"facility":154,"status":125,"city":142,"state":80,"zip":155,"country":128,"countryCode":129,"cosmosGeoPoint":156,"geoPoint":158,"contacts":159},"Institut du Cancer d'Avignon","84918",{"type":131,"coordinates":157},[146,147],{"lat":147,"lon":146},[160],{"name":161,"role":115,"phone":80,"phoneExt":80,"email":162},"Magali RAVOIRE","m.ravoire@isc84.org",{"facility":164,"status":165,"city":166,"state":80,"zip":167,"country":128,"countryCode":129,"cosmosGeoPoint":168,"geoPoint":172,"contacts":173},"CH Bastia","NOT_YET_RECRUITING","Bastia","20600",{"type":131,"coordinates":169},[170,171],9.45123,42.70219,{"lat":171,"lon":170},[174],{"name":175,"role":115,"phone":80,"phoneExt":80,"email":176},"Pascal THOMAS","pascal.thomas@ch-bastia.fr",{"facility":178,"status":125,"city":179,"state":80,"zip":180,"country":128,"countryCode":129,"cosmosGeoPoint":181,"geoPoint":185,"contacts":186},"Oncologie Thoracique Hôpital Morvan","Brest","29200",{"type":131,"coordinates":182},[183,184],-4.48628,48.39029,{"lat":184,"lon":183},[187],{"name":188,"role":115,"phone":80,"phoneExt":80,"email":189},"Renaud DESCOURT","renaud.descourt@chu-brest.fr",{"facility":191,"status":165,"city":192,"state":80,"zip":193,"country":128,"countryCode":129,"cosmosGeoPoint":194,"geoPoint":198,"contacts":199},"Pneumologie Centre François Baclesse","Caen","14000",{"type":131,"coordinates":195},[196,197],-0.35912,49.18585,{"lat":197,"lon":196},[200],{"name":201,"role":115,"phone":80,"phoneExt":80,"email":202},"Hubert CURCIO","h.curcio@baclesse.unicncer.fr",{"facility":204,"status":125,"city":205,"state":80,"zip":206,"country":128,"countryCode":129,"cosmosGeoPoint":207,"geoPoint":211,"contacts":212},"CH Métropole-Savoie","Chambéry","73000",{"type":131,"coordinates":208},[209,210],5.92079,45.56628,{"lat":210,"lon":209},[213],{"name":214,"role":115,"phone":80,"phoneExt":80,"email":215},"Julian PINSOLLE","julian.pinsolle@ch-metropole-savoie.fr",{"facility":217,"status":125,"city":218,"state":80,"zip":219,"country":128,"countryCode":129,"cosmosGeoPoint":220,"geoPoint":224,"contacts":225},"Centre Hospitalier du Cotentin","Cherbourg","50102",{"type":131,"coordinates":221},[222,223],-1.61636,49.63984,{"lat":223,"lon":222},[226],{"name":227,"role":115,"phone":80,"phoneExt":80,"email":228},"Laure KALUZINSKI","l.kaluzinski@ch-cotentin.fr",{"facility":230,"status":165,"city":231,"state":80,"zip":232,"country":128,"countryCode":129,"cosmosGeoPoint":233,"geoPoint":237,"contacts":238},"CHU Hôpital Montpied","Clermont-Ferrand","63000",{"type":131,"coordinates":234},[235,236],3.08682,45.77969,{"lat":236,"lon":235},[239],{"name":240,"role":115,"phone":80,"phoneExt":80,"email":241},"Patrick MERLE","pmerle@chu-clermontferrand.fr",{"facility":243,"status":125,"city":244,"state":80,"zip":245,"country":128,"countryCode":129,"cosmosGeoPoint":246,"geoPoint":250,"contacts":251},"Pneumologie Hospices Civils de Colmar","Colmar","68024",{"type":131,"coordinates":247},[248,249],7.35584,48.08078,{"lat":249,"lon":248},[252],{"name":253,"role":115,"phone":80,"phoneExt":80,"email":254},"Lionel MOREAU","lionel.moreau@ch-colmar.fr",{"facility":256,"status":125,"city":257,"state":80,"zip":258,"country":128,"countryCode":129,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"Pneumologie CHI Creteil","Créteil","94010",{"type":131,"coordinates":260},[261,262],2.46569,48.79266,{"lat":262,"lon":261},[265],{"name":266,"role":115,"phone":80,"phoneExt":80,"email":267},"Isabelle MONNET","isabelle.monnet@chicreteil.fr",{"facility":269,"status":125,"city":270,"state":80,"zip":271,"country":128,"countryCode":129,"cosmosGeoPoint":272,"geoPoint":276,"contacts":277},"CH Elbeuf","Elbeuf","76503",{"type":131,"coordinates":273},[274,275],1.00288,49.28669,{"lat":275,"lon":274},[278],{"name":279,"role":115,"phone":80,"phoneExt":80,"email":280},"Pierre Alexandre HAUSS","Pierre-Alexandre.Hauss@chi-elbeuf-louviers.fr",{"facility":282,"status":165,"city":283,"state":80,"zip":284,"country":128,"countryCode":129,"cosmosGeoPoint":285,"geoPoint":289,"contacts":290},"Polyclinique de Blois","La Chaussée-Saint-Victor","41260",{"type":131,"coordinates":286},[287,288],1.36765,47.61621,{"lat":288,"lon":287},[291],{"name":292,"role":115,"phone":80,"phoneExt":80,"email":293},"Philippe LAPLAIGE","dr.laplaige@wanadoo.fr",{"facility":295,"status":125,"city":296,"state":80,"zip":297,"country":128,"countryCode":129,"cosmosGeoPoint":298,"geoPoint":302,"contacts":303},"CHD Les Oudairies","La Roche-sur-Yon","85000",{"type":131,"coordinates":299},[300,301],-1.42757,46.66974,{"lat":301,"lon":300},[304],{"name":305,"role":115,"phone":80,"phoneExt":80,"email":306},"Acya BIZIEUX","acya.bizieux@ght85.fr",{"facility":308,"status":125,"city":309,"state":80,"zip":310,"country":128,"countryCode":129,"cosmosGeoPoint":311,"geoPoint":315,"contacts":316},"CH La Rochelle","La Rochelle","17000",{"type":131,"coordinates":312},[313,314],-1.15222,46.16308,{"lat":314,"lon":313},[317],{"name":318,"role":115,"phone":80,"phoneExt":80,"email":319},"Marion LAFARGE","marion.lafarge@ght-atlantique17.fr",{"facility":321,"status":125,"city":322,"state":80,"zip":323,"country":128,"countryCode":129,"cosmosGeoPoint":324,"geoPoint":328,"contacts":329},"Hôpital A. Mignot","Le Chesnay","78157",{"type":131,"coordinates":325},[326,327],2.12213,48.8222,{"lat":327,"lon":326},[330],{"name":331,"role":115,"phone":80,"phoneExt":80,"email":332},"Cécile DUJON","Cdujon@ght78sud.fr",{"facility":334,"status":125,"city":335,"state":80,"zip":336,"country":128,"countryCode":129,"cosmosGeoPoint":337,"geoPoint":341,"contacts":342},"Hôpital Robert Boulin","Libourne","33505",{"type":131,"coordinates":338},[339,340],-0.24186,44.91449,{"lat":340,"lon":339},[343],{"name":344,"role":115,"phone":80,"phoneExt":80,"email":345},"Samir ABDICHE","menouar-samir.abdiche@ch-libourne.fr",{"facility":347,"status":125,"city":348,"state":80,"zip":349,"country":128,"countryCode":129,"cosmosGeoPoint":350,"geoPoint":354,"contacts":355},"CHU Dupuytren","Limoges","87042",{"type":131,"coordinates":351},[352,353],1.24759,45.83362,{"lat":353,"lon":352},[356],{"name":357,"role":115,"phone":80,"phoneExt":80,"email":358},"Yannick SIMONNEAU","yannick.simonneau@chu-limoges.fr",{"facility":360,"status":125,"city":361,"state":80,"zip":362,"country":128,"countryCode":129,"cosmosGeoPoint":363,"geoPoint":367,"contacts":368},"Hôpital de la Vallée - Service Pneumologie","Longjumeau","91160",{"type":131,"coordinates":364},[365,366],2.29431,48.69307,{"lat":366,"lon":365},[369],{"name":370,"role":115,"phone":80,"phoneExt":80,"email":371},"Alain BAKEBE","a.bakebe@gh-nord-essonne.fr",{"facility":373,"status":125,"city":374,"state":80,"zip":375,"country":128,"countryCode":129,"cosmosGeoPoint":376,"geoPoint":380,"contacts":381},"Centre Léon Bérard","Lyon","69373",{"type":131,"coordinates":377},[378,379],4.84789,45.74906,{"lat":379,"lon":378},[382],{"name":383,"role":115,"phone":80,"phoneExt":80,"email":384},"Chantal DECROISETTE","chantal.decroisette@lyon.unicancer.fr",{"facility":386,"status":125,"city":387,"state":80,"zip":388,"country":128,"countryCode":129,"cosmosGeoPoint":389,"geoPoint":393,"contacts":394},"Hôpital Européen de Marseille","Marseille","13003",{"type":131,"coordinates":390},[391,392],5.38107,43.29695,{"lat":392,"lon":391},[395],{"name":396,"role":115,"phone":80,"phoneExt":80,"email":397},"Jacques LE TREUT","j.letreut@hopital-europeen.fr",{"facility":399,"status":125,"city":387,"state":80,"zip":400,"country":128,"countryCode":129,"cosmosGeoPoint":401,"geoPoint":403,"contacts":404},"Oncologie Thoracique Hôpital Nord","13915",{"type":131,"coordinates":402},[391,392],{"lat":392,"lon":391},[405],{"name":406,"role":115,"phone":80,"phoneExt":80,"email":407},"Laurent GREILLIER","laurent.greillier@ap-hm.fr",{"facility":409,"status":125,"city":410,"state":80,"zip":411,"country":128,"countryCode":129,"cosmosGeoPoint":412,"geoPoint":416,"contacts":417},"GHEF Site de Meaux","Meaux","77100",{"type":131,"coordinates":413},[414,415],2.87885,48.96014,{"lat":415,"lon":414},[418],{"name":419,"role":115,"phone":80,"phoneExt":80,"email":420},"Chrystèle LOCHER","chlocher@ghef.fr",{"facility":422,"status":125,"city":423,"state":80,"zip":424,"country":128,"countryCode":129,"cosmosGeoPoint":425,"geoPoint":429,"contacts":430},"Centre d Oncologie de Gentilly","Nancy","54000",{"type":131,"coordinates":426},[427,428],6.18496,48.68439,{"lat":428,"lon":427},[431],{"name":432,"role":115,"phone":80,"phoneExt":80,"email":433},"Laurene GAVOILLE","L.gavoille@oncog.fr",{"facility":435,"status":125,"city":436,"state":80,"zip":437,"country":128,"countryCode":129,"cosmosGeoPoint":438,"geoPoint":442,"contacts":443},"Pneumologie CHR","Orléans","45067",{"type":131,"coordinates":439},[440,441],1.90407,47.90248,{"lat":441,"lon":440},[444],{"name":445,"role":115,"phone":80,"phoneExt":80,"email":446},"Hugues MOREL","hugues.morel@chr-orleans.fr",{"facility":448,"status":165,"city":449,"state":80,"zip":450,"country":128,"countryCode":129,"cosmosGeoPoint":451,"geoPoint":455,"contacts":456},"Pneumologie Hôpital Cochin","Paris","75014",{"type":131,"coordinates":452},[453,454],2.3488,48.85341,{"lat":454,"lon":453},[457],{"name":458,"role":115,"phone":80,"phoneExt":80,"email":459},"Marie WISLEZ","marie.wislez@aphp.fr",{"facility":461,"status":165,"city":449,"state":80,"zip":462,"country":128,"countryCode":129,"cosmosGeoPoint":463,"geoPoint":465,"contacts":466},"Pneumologie Hôpital Tenon","75970",{"type":131,"coordinates":464},[453,454],{"lat":454,"lon":453},[467],{"name":468,"role":115,"phone":80,"phoneExt":80,"email":469},"Constance METEYE","constance.meteye@aphp.fr",{"facility":471,"status":165,"city":472,"state":80,"zip":473,"country":128,"countryCode":129,"cosmosGeoPoint":474,"geoPoint":478,"contacts":479},"Cantre Catalan d Oncologie","Perpignan","66000",{"type":131,"coordinates":475},[476,477],2.89541,42.69764,{"lat":477,"lon":476},[480],{"name":481,"role":115,"phone":80,"phoneExt":80,"email":482},"Sabine VIEILLOT","sabinevieillot@gmail.com",{"facility":484,"status":125,"city":485,"state":80,"zip":486,"country":128,"countryCode":129,"cosmosGeoPoint":487,"geoPoint":491,"contacts":492},"CH Annecy Genevois","Pringy","74374",{"type":131,"coordinates":488},[489,490],6.12608,45.94622,{"lat":490,"lon":489},[493],{"name":494,"role":115,"phone":80,"phoneExt":80,"email":495},"Emilie PLUQUET","epluquet@ch-annecygenevois.fr",{"facility":497,"status":125,"city":498,"state":80,"zip":499,"country":128,"countryCode":129,"cosmosGeoPoint":500,"geoPoint":504,"contacts":505},"Pneumologie CHI Quimper","Quimper","29000",{"type":131,"coordinates":501},[502,503],-4.09795,47.99597,{"lat":503,"lon":502},[506],{"name":507,"role":115,"phone":80,"phoneExt":80,"email":117},"Romain CORRE",{"facility":509,"status":125,"city":510,"state":80,"zip":511,"country":128,"countryCode":129,"cosmosGeoPoint":512,"geoPoint":516,"contacts":517},"CHU Hôpital Ponchailloux","Rennes","35033",{"type":131,"coordinates":513},[514,515],-1.67431,48.11109,{"lat":515,"lon":514},[518],{"name":519,"role":115,"phone":80,"phoneExt":80,"email":520},"Charles RICORDEL","charles.ricordel@chu-rennes.fr",{"facility":522,"status":165,"city":523,"state":80,"zip":524,"country":128,"countryCode":129,"cosmosGeoPoint":525,"geoPoint":529,"contacts":530},"Pneumologie Hôpital Charles Nicolle","Rouen","76031",{"type":131,"coordinates":526},[527,528],1.09932,49.44313,{"lat":528,"lon":527},[531],{"name":532,"role":115,"phone":80,"phoneExt":80,"email":533},"Florian GUISIER","florian.guisier@chu-rouen.fr",{"facility":535,"status":125,"city":536,"state":80,"zip":537,"country":128,"countryCode":129,"cosmosGeoPoint":538,"geoPoint":542,"contacts":543},"Pneumologie CHU Felix Guyon","Saint-Denis","97400",{"type":131,"coordinates":539},[540,541],2.35387,48.93564,{"lat":541,"lon":540},[544],{"name":545,"role":115,"phone":80,"phoneExt":80,"email":546},"Diane MOREAU","diane.moreau@chu-reunion.fr",{"facility":548,"status":125,"city":549,"state":80,"zip":550,"country":128,"countryCode":129,"cosmosGeoPoint":551,"geoPoint":555,"contacts":556},"Pneumologie CHU St Etienne","Saint-Etienne","42270",{"type":131,"coordinates":552},[553,554],4.39,45.43389,{"lat":554,"lon":553},[557],{"name":558,"role":115,"phone":80,"phoneExt":80,"email":559},"Sophie BAYLE-BLEUEZ","sophie.bayle@chu-st-etienne.fr",{"facility":561,"status":125,"city":562,"state":80,"zip":563,"country":128,"countryCode":129,"cosmosGeoPoint":564,"geoPoint":568,"contacts":569},"Clinique Mutualiste","Saint-Nazaire","44600",{"type":131,"coordinates":565},[566,567],-2.2179,47.27506,{"lat":567,"lon":566},[570],{"name":571,"role":115,"phone":80,"phoneExt":80,"email":572},"Thierry CHATELLIER","thierry.chatellier@hospigrandouest.fr",{"facility":574,"status":125,"city":575,"state":80,"zip":576,"country":128,"countryCode":129,"cosmosGeoPoint":577,"geoPoint":581,"contacts":582},"CHU de la 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BYLICKI","bylicki.olivier@yahoo.fr",{"facility":613,"status":125,"city":601,"state":80,"zip":614,"country":128,"countryCode":129,"cosmosGeoPoint":615,"geoPoint":617,"contacts":618},"CHITS Toulon Sainte Musse","83056",{"type":131,"coordinates":616},[605,606],{"lat":606,"lon":605},[619],{"name":620,"role":115,"phone":80,"phoneExt":80,"email":621},"Clarisse AUDIGIER VALETTE","clarisse.audigier-valette@ch-toulon.fr",{"facility":623,"status":125,"city":624,"state":80,"zip":625,"country":128,"countryCode":129,"cosmosGeoPoint":626,"geoPoint":630,"contacts":631},"Oncologie CHBA","Vannes","56000",{"type":131,"coordinates":627},[628,629],-2.76205,47.65688,{"lat":629,"lon":628},[632],{"name":633,"role":115,"phone":80,"phoneExt":80,"email":634},"Gonzague DE CHABOT","gonzague.dechabot@ch-bretagne-atlantique.fr",{"facility":636,"status":125,"city":637,"state":80,"zip":638,"country":128,"countryCode":129,"cosmosGeoPoint":639,"geoPoint":643,"contacts":644},"Hôpital Nord OUest","Villefranche-sur-Saône","69655",{"type":131,"coordinates":640},[641,642],4.71961,45.98967,{"lat":642,"lon":641},[645],{"name":646,"role":115,"phone":80,"phoneExt":80,"email":647},"Lionel FALCHERO","LFalchero@lhopitalnordouest.fr",{"type":649,"investigatorFullName":80,"investigatorTitle":80,"investigatorAffiliation":80,"oldNameTitle":80,"oldOrganization":80},"SPONSOR","100565768",false,"NCT06646471","PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies","PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly","PROMETHEE","Inclusion Criteria:\n\n* Patient ≥70 years\n* Non-small-cell lung cancer for which the multidisciplinary consultation required systemic treatment regardless of Tumor-Node-Metastasis (TNM) stage\n* Patient naïve to systemic anticancer treatment for bronchial neoplasia\n* Patient covered by social security\n* Patient eligible for systemic treatment\n* Systemic treatment with marketing authorization in the indication, available in routine care early access or compassionate access.\n* Patient able to understand the protocol\n* Patient not opposed to the collection of data concerning him\u002Fher\n* Signature of study consent form.\n\nExclusion Criteria:\n\n* Patients under guardians or curators\n* Patient not under the care of the investigating center and not monitored by the investigating center\n* Patient already treated with systemic therapy for NSCLC","ALL","70 Years",{"count":660,"type":661},500,"ESTIMATED","INTERVENTIONAL",[664],"PHASE4","The objective of the study is to prospectively generate real-life data in patients aged ≥70 years treated in first line for a thoracic tumor (Non-Small-Cell Lung Carcinoma) according to best standard of care as defined by the European Society for Medical Oncology (ESMO). This cohort will aim to:\n\n* characterize participants in terms of geriatrics, biology and carcinology\n* describe the treatment modalities by stage, as well as the results in terms of efficacy, safety and impact on quality of life.\n\nAt the same time, exploratory sub-cohorts will be identified including participants treated uniformly with the same molecule, and\u002For the same innovative strategy.\n\nParticipants will be followed in accordance with investigator's usual clinical practice at the corresponding site. They will be asked to:\n\n* visit the clinic as per physician's request for checkups and tests for assessing general condition and clinical efficacy and tolerance of current treatment.\n* perform the necessary regular para-clinical examinations (lab testing, imaging, re-biopsy).\n* provide blood samples for bio-bank repository\n* perform assessments specific to older adults\n* answer three quality of life questionnaires",[667,668],"Non Small Cell Lung Cancer","Lung Cancer","2026-04-24",{"date":671,"type":672},"2026-04-29","ACTUAL",{"date":674,"type":672},"2024-09-26",{"date":676,"type":661},"2028-08-31",{"name":678,"class":6},"GFPC Investigation",41]